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  1. 256521
    “…This study analyzed the effects of exercise training in an animal model of respiratory chain complex I deficiency, the Harlequin (Hq) mouse, which replicates the clinical features of this condition. …”
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    Physical Exercise and Mitochondrial Disease: Insights From a Mouse Model
  2. 256522
    “…Further network analysis showed that 0–1 mg/kg MK-801 may be the optimal dose for treatment in the middle cerebral artery occlusion animal model. CONCLUSION: MK-801 effectively reduces brain lesion volume and the degree of cerebral edema in rat models of experimental acute brain injury, providing a good neuroprotective effect. …”
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    MK-801 attenuates lesion expansion following acute brain injury in rats: a meta-analysis
  3. 256523
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    Motivation of Owners to Purchase Pedigree Cats, with Specific Focus on the Acquisition of Brachycephalic Cats
  4. 256524
    “…METHODS: We induced solid tumor in C57BL/6 mice by subcutaneous injection of B16F10 cell line (1 X 10(6) cells) and monitored the tumor growth. Animals were given an intraperitoneal injection of α-GalCer (2 μg/injection) in 200 μl PBS on day + 1, + 5, + 10, + 15, and + 20 (with respect to tumor cell injection). …”
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    Natural killer T cell activation increases iNOS(+)CD206(-) M1 macrophage and controls the growth of solid tumor
  5. 256525
    por Shoji, Hirotaka, Miyakawa, Tsuyoshi
    Publicado 2019
    “…These changes, with stress before pregnancy, are potential risk factors for the development of postpartum depression (PPD). A valid animal model of PPD is needed to understand the neurobiological basis of the depressive state of females. …”
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    Increased depression-related behavior during the postpartum period in inbred BALB/c and C57BL/6 strains
  6. 256526
    “…Further studies are needed to elucidate mechanisms of adrenal steroidal hormone synthesis and secretion in response to various stressful stimuli in both neutered and intact animals.…”
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    Cortisol, progesterone, 17α-hydroxyprogesterone, and TSH responses in dogs injected with low-dose lipopolysaccharide
  7. 256527
    “…Salmonella is a common and important pathogen for both human and animals. All Salmonella except Salmonella pullorum and Salmonella gallinarum have flagellum. …”
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    A promising detection candidate for flagellated Salmonella spp.
  8. 256528
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    Enterococcus faecium NCIMB 10415 administration improves the intestinal health and immunity in neonatal piglets infected by enterotoxigenic Escherichia coli K88
  9. 256529
    “…Preclinical research in animals with intact immune systems has shown that NIT-PIT targeting of immunosuppressor cells within the tumor, such as regulatory T-cells, can further enhance tumor-cell-selective systemic host-immunity leading to significant responses in distant metastatic tumors, which are not treated with light. …”
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    Near-Infrared Photoimmunotherapy of Cancer
  10. 256530
    “…Concomitantly, NLRP3 immunoreactivity was lower in the RPE layer of animals fed with ATAC. In mice where caspase-1 cleavage was impaired by the genetic deficiency in caspase-4, the XIAP protein level increased in eye tissues. …”
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    The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis
  11. 256531
    “…Moreover, physical stimulation has shown the ability to prevent bone loss induced by functional disuse and estrogen deficiency in animal models. However, its treatment capability is unclear. …”
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    Quantitative ultrasound imaging monitoring progressive disuse osteopenia and mechanical stimulation mitigation in calcaneus region through a 90-day bed rest human study
  12. 256532
    “…Basso, Beattie and Bresnahan (BBB) behavioral test scores were used to evaluate the motor function of all animals before and after the SCI weekly through the 8th week. …”
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    Co-Transplantation of Human Umbilical Cord Mesenchymal Stem Cells and Human Neural Stem Cells Improves the Outcome in Rats with Spinal Cord Injury
  13. 256533
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    Effects of Dietary Betaine on Growth Performance, Digestive Function, Carcass Traits, and Meat Quality in Indigenous Yellow-Feathered Broilers under Long-Term Heat Stress
  14. 256534
    “…For each experiment, both kidneys of one animal were perfused simultaneously with a 1:1 mixture of autologous blood and modified Ringer’s solution at 38 °C and 75 mmHg continuous perfusion pressure. …”
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    Influence of Vitamin C on Antioxidant Capacity of In Vitro Perfused Porcine Kidneys
  15. 256535
    “…Upon infection of DEF cells pre-treated with trypsin, DAstV-1 mRNA copies were identified after serial passaging, and the result showed that rDAstV-1 and pDAstV-1 shared similar replication kinetics. Animal experiment showed that the rDAstV-1 had an extensive tissue tropism, and the virus was capable of invading both the central and the peripheral immune organs in infected ducklings. …”
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    A novel method to rescue and culture duck Astrovirus type 1 in vitro
  16. 256536
    “…BACKGROUND: Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) experience dramatic changes in physiological and molecular parameters during winter hibernation. Notably, these animals experience reduced blood circulation during torpor, which can put numerous stresses on their hearts. …”
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    The heart of a hibernator: EGFR and MAPK signaling in cardiac muscle during the hibernation of thirteen-lined ground squirrels, Ictidomys tridecemlineatus
  17. 256537
    “…A number of studies have shown variable grades of cytotoxicity and genotoxicity in in vitro cell cultures, laboratory animals and humans when directly exposed to particle debris generated from tires. …”
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    Exposure to particle debris generated from passenger and truck tires induces different genotoxicity and inflammatory responses in the RAW 264.7 cell line
  18. 256538
    “…Early ARV initiation reduced T-cell immune activation, as assessed by HLA-DR/CD39 expression, and prevented the depletion of memory CCR6(+) Th17 cells in both blood and MLNs. Untreated animals showed higher frequencies of Tregs, CD39(+) Tregs, thymic Tregs, and new memory CD4 populations sharing similarity with Tregs as CTLA4(+) PD1(–) and CTLA4(+) PD1(–) FoxP3(+) T cells. …”
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    Differential Dynamics of Regulatory T-Cell and Th17 Cell Balance in Mesenteric Lymph Nodes and Blood following Early Antiretroviral Initiation during Acute Simian Immunodeficiency Virus Infection
  19. 256539
    por Fu, Miao, Meng, Lan, Ren, Hao, Luo, Fang
    Publicado 2019
    “…PRF is advantageous because it does not damage nerves and avoids sensory loss after treatment. At present, animal studies have demonstrated that PRF is safe and effective for relieving the NP associated with sciatic nerve damage in rats with chronic constriction injury (CCI). …”
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    Pulsed radiofrequency inhibits expression of P2X(3) receptors and alleviates neuropathic pain induced by chronic constriction injury in rats
  20. 256540
    “…Furthermore, in vivo acute oral toxicity test revealed no signs of toxicity and mortality in treated animal models compared to the control group. Collectively, the promising inhibitory effect and molecular and mechanistic evidence of antiproliferative activity of Mn(III) complex and its safety characterization have demonstrated that it may have therapeutic value in breast cancer treatment worthy of further investigation and development.…”
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    In vivo acute toxicity evaluation and in vitro molecular mechanism study of antiproliferative activity of a novel indole Schiff base β-diiminato manganese(III) complex in hormone-dependent and triple negative breast cancer cells
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