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258101
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258102por Agerholm, Jørgen S., Menzi, Fiona, McEvoy, Fintan J., Jagannathan, Vidhya, Drögemüller, Cord“…Paternal dominant de novo mutations are a risk in cattle breeding, especially because the ratio of defective offspring may be very high and be associated with significant animal welfare problems. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12917-016-0739-z) contains supplementary material, which is available to authorized users.…”
Publicado 2016
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258103por Rochat, Tamsen J., Houle, Brian, Stein, Alan, Coovadia, Hoosen, Coutsoudis, Anna, Desmond, Chris, Newell, Marie-Louise, Bland, Ruth M.“…Factors positively associated with executive function were home stimulation (aOR 1.36 [95% CI 1.0–1.8], p = 0.04, Auditory Attention; aOR 1.35 [95% CI 1.0–1.8], p = 0.05, Response Set) and crèche (aOR 1.74 [95% CI 1.0–3.0], p = 0.05, Animal Sorting). Maternal mental health problems and parenting stress were associated with increased emotional-behavioural problems on the total CBCL (aOR 2.44 [95% CI 1.3–4.6], p = 0.01; aOR 7.04 [95% CI 4.2–11.9], p < 0.001, respectively). …”
Publicado 2016
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258104“…A 5-mg warfarin sodium tablet was dissolved in animals’ drinking water (effective warfarin uptake 0.04 mg (2 mg/kg) per mouse). …”
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258105por Svenningsson, Per, Rosenblad, Carl, af Edholm Arvidsson, Karolina, Wictorin, Klas, Keywood, Charlotte, Shankar, Bavani, Lowe, David A., Björklund, Anders, Widner, Håkan“…Simultaneous activation of 5-HT1A and 5-HT1B receptors effectively blocks l-DOPA-induced dyskinesias in animal models of dopamine depletion, justifying a clinical study with eltoprazine, a 5-HT1A/B receptor agonist, against l-DOPA-induced dyskinesias in patients with Parkinson’s disease. …”
Publicado 2015
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258106por Loftus, Loni, Marks, Kelly, Jones-McVey, Rosie, Gonzales, Jose L., Fowler, Veronica L.Enlace del recurso
Publicado 2016
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258107por Stankevicius, Vaidotas, Vasauskas, Gintautas, Bulotiene, Danute, Butkyte, Stase, Jarmalaite, Sonata, Rotomskis, Ricardas, Suziedelis, Kestutis“…Finally, we validated the microarray data by quantitative PCR in LLC1 cells cultured under 2D or 3D conditions or LLC1 tumors implanted in experimental animals. RESULTS: Microarray gene expression analysis revealed that 1884 genes and 77 miRNAs were significantly altered in LLC1 cells after 48 h cell growth under 2D and ECM based 3D cell growth conditions. …”
Publicado 2016
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258108“…Thus, we sequenced the KCNJ10 exons with their adjacent regions from 10 PRT and 3 JRT including the animals with imperfect co-segregation of the c.627C > G mutation. …”
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258109por Fisher, B.G., Thankamony, A., Hughes, I.A., Ong, K.K., Dunger, D.B., Acerini, C.L.“…WHAT IS ALREADY KNOWN: The increasing prevalence of male reproductive disorders may reflect environmental influences on foetal testicular development during the MPW. Animal and human xenograft studies have demonstrated that paracetamol reduces foetal testicular testosterone production, consistent with reported epidemiological associations between prenatal paracetamol exposure and cryptorchidism. …”
Publicado 2016
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258110por Fitts, Eric C., Andersson, Jourdan A., Kirtley, Michelle L., Sha, Jian, Erova, Tatiana E., Chauhan, Sadhana, Motin, Vladimir L., Chopra, Ashok K.“…Conversely, the administration of AI-2 to mice infected with the ΔrbsA ΔlsrA ΔluxS ΔlsrK mutant did not rescue animals from lethality, indicating the importance of the AI-2–LsrK axis in regulating bacterial virulence. …”
Publicado 2016
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258111“…To address the growing concern over antibiotic-resistant microbial infections in aquatic animals, we tested several promising alternative agents that have emerged as new drug candidates. …”
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258112por Mehaisen, Gamal M. K., Eshak, Mariam G., Elkaiaty, Ahmed M., Atta, Abdel-Rahman M. M., Mashaly, Magdi M., Abass, Ahmed O.“…The current study provides a comprehensive view of different physiological modulations in broiler chickens by CORT treatment and may set the potential means to mount a successful defense against stress in broilers and other animals as well.…”
Publicado 2017
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258113por Severi-Aguiar, Grasiela Dias de Campos, Pinto, Suellen Josine, Capucho, Cristina, Oliveira, Camila Andrea, Diamante, Maria Aparecida, Barbieri, Renata, Predes, Fabrícia Souza, Dolder, Heidi“…BACKGROUND: Human and animal evidence suggests that environmental toxicants may have an adverse impact on male reproductive health, reducing the population's reproductive output. …”
Publicado 2017
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258114por Teixeira, M.M., Moreno, L.F., Stielow, B.J., Muszewska, A., Hainaut, M., Gonzaga, L., Abouelleil, A., Patané, J.S.L., Priest, M., Souza, R., Young, S., Ferreira, K.S., Zeng, Q., da Cunha, M.M.L., Gladki, A., Barker, B., Vicente, V.A., de Souza, E.M., Almeida, S., Henrissat, B., Vasconcelos, A.T.R., Deng, S., Voglmayr, H., Moussa, T.A.A., Gorbushina, A., Felipe, M.S.S., Cuomo, C.A., de Hoog, G. Sybren“…Diseases range from mild cutaneous to fatal cerebral or disseminated infections and affect humans and cold-blooded animals globally. In addition, Chaetothyriales comprise species with aquatic, rock-inhabiting, ant-associated, and mycoparasitic life-styles, as well as species that tolerate toxic compounds, suggesting a high degree of versatile extremotolerance. …”
Publicado 2017
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258115por Vaz, Janice, Narayan, Edward J., Dileep Kumar, R., Thenmozhi, K., Thiyagesan, Krishnamoorthy, Baskaran, Nagarajan“…It is thus necessary to measure biological traits like behaviour, stress physiology, and contextual factors driving the animals maintained at zoos. In this study, we assessed stereotypic behaviour and stress physiology employing standard behaviour scoring, non-invasive stress monitoring, and their contextual drivers in a sub-population of two large felid species managed in six Indian zoos. …”
Publicado 2017
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258116por Mori, Simone, Sugama, Shuei, Nguyen, William, Michel, Tatiana, Sanna, M. Germana, Sanchez-Alavez, Manuel, Cintron-Colon, Rigo, Moroncini, Gianluca, Kakinuma, Yoshihiko, Maher, Pamela, Conti, Bruno“…Markers of oxidative stress, microglia activation, and the number of dopaminergic neurons in IL-13Rα1 knock-out animals (Il13ra1 (Y/−)) and their wild-type littermates (Il13ra1 (Y/+)) were evaluated at 16 weeks of stress and at 20 weeks, following a 4 week non-stressed period and compared to non-stressed mice. …”
Publicado 2017
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258117por Wang, Bing, Wang, Diming, Wu, Xuehui, Cai, Jie, Liu, Mei, Huang, Xinbei, Wu, Jiusheng, Liu, Jianxin, Guan, Leluo“…Our results suggest that particle size may be more important in regulating rumen epithelial morphology when animals are fed with low-quality forage diets and the identified DE genes may affect the RE nutrient absorption or morphology of RE. …”
Publicado 2017
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258118“…Tumor growth was significantly blocked by overexpressing PlncRNA-1 in C4-2 cells and by the TGF-β1 inhibitor LY2109761 in animal experiments. MATERIALS AND METHODS: The expression levels of PlncRNA-1 and TGF-β1 were analyzed in 19 prostate cancer tissue samples and in adjacent normal tissue samples, 4 Pca cell lines, including LNCaP, C4-2, DU145, and PC3, and 1 normal prostate epithelial cell line RWPE-1. …”
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258119por Agostini, Francesco, Polesel, Jerry, Battiston, Monica, Lombardi, Elisabetta, Zanolin, Stefania, Da Ponte, Alessandro, Astori, Giuseppe, Durante, Cristina, Mazzucato, Mario“…BACKGROUND: Standardized animal-free components are required for manufacturing cell-based medicinal products. …”
Publicado 2017
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258120por Yamamoto, Tokihiro, Kent, Michael S., Wisner, Erik R., Johnson, Lynelle R., Stern, Joshua A., Qi, Lihong, Fujita, Yukio, Boone, John M.“…In a protocol approved by the institutional animal care and use committee, the authors acquired CT scans in the prone position for a total of 14 anesthetized canines (seven canines with normal lungs and seven canines with diseased lungs). …”
Publicado 2016
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