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258261por Xu, Yanjun, De Rosa, Maria Caterina, Quarta, Carmelo, Fisette, Alexander, Rausch, Richard, Fleischman, Amy Debra, Tschöp, Matthias H, García-Cáceres, Cristina, Hirschhorn, Joel N, Doege, Claudia A, Thaker, Vidhu V“…Introduction: Tbx3 has been shown to play a role in the terminal specification of hypothalamic melanocortin neurons during neonatal development & in maintaining the plasticity of their peptidergic role in adulthood in animal experiments (1). The absence of humans with biallelic mutations in TBX3 & the conservation of the critical domains across species emphasizes its essential role in life. …”
Publicado 2020
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258262por Subramaniyan, Sivakumar Allur, Kang, Darae, Siddiqui, Sharif Hasan, Park, Jinryong, Tian, Weishun, Park, Byungyong, Shim, KwanseobEnlace del recurso
Publicado 2020
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258263
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258264por Weise, Florian J., Tomeletso, Mathata, Stein, Andrew B., Somers, Michael J., Hayward, Matt W.Enlace del recurso
Publicado 2020
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258265“…The GCR simulator exposes state-of-the art cellular and animal model systems to 33 sequential beams including 4 proton energies plus degrader, 4 helium energies plus degrader, and the 5 heavy ions of C, O, Si, Ti, and Fe. …”
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258266
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258267por Lin, Gang, Guo, Yang, Liu, Bing, Wang, Ruiguo, Su, Xiaoou, Yu, Dongyou, He, PingliEnlace del recurso
Publicado 2020
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258268por Gurung, Sunam, Nadeau, Hugh, Maxted, Marta, Peregrine, Jamie, Reuter, Darlene, Norris, Abby, Edwards, Rodney, Hyatt, Kimberly, Singleton, Krista, Papin, James F., Myers, Dean A.“…Maternal blood, saliva, and cervicovaginal wash (CVW) samples were obtained. Animals were euthanized at 28 days (n = 5) or 39 days (n = 1) after the initial inoculation, and maternal/fetal tissues were collected. …”
Publicado 2020
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258269por Borges, Alana Azevedo, Lira, Gabriela Pereira De Oliveira, Nascimento, Lucas Emanuel, Santos, Maria Valéria De Oliveira, Oliveira, Moacir Franco De, Silva, Alexandre Rodrigues, Pereira, Alexsandra Fernandes“…METHODS: Skin biopsies were collected from the peripheral ear region from five adult animals in captivity. Initially, cells were isolated from fragments and cultured in the Dulbecco’s modified Eagle medium supplemented with 10% fetal bovine serum and 2% antibiotic–antimycotic solution under a controlled atmosphere (38.5 °C, 5% CO(2)). …”
Publicado 2020
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258270por Zhang, Xin, Wang, Yifan, Wang, Mengzhi, Zhou, Gang, Chen, Lianmin, Ding, Luoyang, Bu, Dengpan, Loor, JuanEnlace del recurso
Publicado 2020
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258271
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258272por Vadopalas, Laurynas, Ruzauskas, Modestas, Lele, Vita, Starkute, Vytaute, Zavistanaviciute, Paulina, Zokaityte, Egle, Bartkevics, Vadims, Badaras, Sarunas, Klupsaite, Dovile, Mozuriene, Erika, Dauksiene, Agila, Sidlauskiene, Sonata, Gruzauskas, Romas, Bartkiene, ElenaEnlace del recurso
Publicado 2020
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258273“…Here, to investigate age‐related behavioral changes from young to old age in mice, we analyzed the behaviors of male C57BL/6J mice from four different age groups (8, 47, 73, and 99 weeks of age at the beginning of the experiment) from a colony that had been maintained in a genetically controlled condition based on The Jackson Laboratory's Genetic Stability Program in an environmentally controlled animal facility. METHODS: We used a battery of behavioral tests, including the light/dark transition, open field, elevated plus maze, hot plate, social interaction, rotarod, three‐chamber social approach, prepulse inhibition, Porsolt forced swim, T‐maze, Barnes maze, tail suspension, and fear‐conditioning tests. …”
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258274por Colombino, Elena, Ferrocino, Ilario, Biasato, Ilaria, Cocolin, Luca Simone, Prieto-Botella, Daniel, Zduńczyk, Zenon, Jankowski, Jan, Milala, Joanna, Kosmala, Monika, Fotschki, Bartosz, Capucchio, Maria Teresa, Juśkiewicz, JerzyEnlace del recurso
Publicado 2020
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258275por Priosoeryanto, Bambang Pontjo, Rostantinata, Riski, Harlina, Eva, Nurcholis, Waras, Ridho, Rachmi, Sutardi, Lina Noviyanti“…BACKGROUND AND AIM: Tumor disorder is one of the degenerative diseases that affected human and animals and recently is tend to increase significantly. …”
Publicado 2020
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258276por Mendoza, S. M., Boyd, R. D., Remus, J., Wilcock, P., Martinez, G. E., van Heugten, E.Enlace del recurso
Publicado 2020
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258277por Gergely, Anna, Kiss, Orsolya, Reicher, Vivien, Iotchev, Ivaylo, Kovács, Enikő, Gombos, Ferenc, Benczúr, András, Galambos, Ágoston, Topál, József, Kis, AnnaEnlace del recurso
Publicado 2020
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258278Publicado 2018“…Moreover, in a human leukemia xenograft animal model, the results showed that mice in the untransduced T cells group and the control virus transduced T cells group all died within 20 to 30 days, and the hCART19 cell group survived >40 days, which was more than the survival time of the other two groups of mice. …”
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258279por Fisher, Kimone Leigh, Mabuka, Jennifer M., Sivro, Aida, Ngcapu, Sinaye, Passmore, Jo-Ann Shelley, Osman, Farzana, Ndlovu, Bongiwe, Abdool Karim, Quarraisha, Abdool Karim, Salim S., Chung, Amy W., Baxter, Cheryl, Archary, Derseree“…Since pre-exposure prophylaxis (PrEP) and HIV-vaccines are being used as a combination prevention strategy in at risk populations, the effects of PrEP on nNAb functions both mucosally and systemically remain undefined. Previous animal and human studies demonstrated reduced HIV-specific antibody binding avidity post-HIV seroconversion with PrEP, which in turn may affect antibody functionality. …”
Publicado 2020
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258280“…We used 9-month-old 5XFAD mice (an Alzheimer’s disease model) treated for 6 months with the anti-HIV drug efavirenz. These animals have previously been shown to have improved behavioural performance, increased cytochrome P450 46A1 activity in the brain, and increased sterol flux through the plasma membranes. …”
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