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259301“…Phylogenetic analysis based on 18S rDNA or ITS1 sequences placed this parasite close to Sarcocystis spp. that utilize small animals as intermediate hosts and snakes as the known or presumed definitive host. …”
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259302por Noormohammadi, Morvarid, Ghorbani, Zeinab, Naser Moghadasi, Abdorreza, Saeedirad, Zahra, Shahemi, Sahar, Ghanaatgar, Milad, Rezaeimanesh, Nasim, Hekmatdoost, Azita, Ghaemi, Amir, Razeghi Jahromi, Soodeh“…RESULTS: There was significant difference between RRMS and control groups in the median (Q1-Q3) of age (years, P value < 0.001), body mass index (BMI) (kg/m(2), P value < 0.001), and total intake of calories (kcal, P value = 0.032), carbohydrates (g, P value = 0.003), animal-based protein (g, P value = 0.009), and fiber (g, P value = 0.001). …”
Publicado 2022
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259303por Edvinsson, Jacob C. A., Maddahi, Aida, Christiansen, Isabella M., Reducha, Philip V., Warfvinge, Karin, Sheykhzade, Majid, Edvinsson, Lars, Haanes, Kristian A.“…Selective agonists targeting these receptors, such as triptans and ditans, are effective in aborting acute migraine attacks and inhibit the in vivo release of calcitonin gene-related peptide (CGRP) in human and animal models. The study aimed to examine the localization, genetic expression and functional aspects of 5- HT(1B/1D/1F) receptors in the trigeminal system in order to further understand the molecular sites of action of triptans (5-HT(1B/1D)) and ditans (5-HT(1F)). …”
Publicado 2022
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259304“…METHODS: Studies investigating miRNA alterations in all species of animal models and human studies of acute, traumatic SCI will be identified from PubMed, Embase, and Scopus. …”
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259305por Jiang, Rongrong, Huang, Jiechun, Sun, Xiaotian, Chu, Xianglin, Wang, Fangrui, Zhou, Jie, Fan, Qihui, Pang, Liewen“…The traditional 2-D culture method cannot reveal the interaction between cells and the surrounding extracellular matrix during invasion process, while the animal models usually are too complex to explain mechanisms in detail. …”
Publicado 2022
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259306por Wang, Xiaoyu, Lu, Xiansheng, Wang, Ping, Chen, Qiaoyu, Xiong, Le, Tang, Minshan, Hong, Chang, Lin, Xiaowen, Shi, Kaixi, Liang, Li, Lin, Jie“…METHODS: CRC cell lines and clinical tissue samples were used. qRT-PCR, Western blotting, immunohistochemistry (IHC), gain- and loss-of-function assays, animal xenograft model studies, bioinformatic analysis, methylated single-stranded RNA affinity assays, gene-specific m6A quantitative qRT-PCR, dual-luciferase reporter assays and RNA stability assays were performed in this study. …”
Publicado 2022
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259307por Machamer, James B., Vazquez-Cintron, Edwin J., O’Brien, Sean W., Kelly, Kyle E., Altvater, Amber C., Pagarigan, Kathleen T., Dubee, Parker B., Ondeck, Celinia A., McNutt, Patrick M.“…While neurotransmission was nearly eliminated at 5 d, neurotransmission was significantly improved at 21 d in 3,4-DAP-infused survivors, although still depressed compared to naïve rats. 3,4-DAP is the first small molecule to reverse systemic paralysis and promote survival in animal models of botulism, thereby meeting a critical treatment need that is not addressed by post-exposure prophylaxis with conventional antitoxin. …”
Publicado 2022
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259308por Chuntova, Pavlina, Yamamichi, Akane, Chen, Tiffany, Narayanaswamy, Rohini, Ronseaux, Sebastien, Hudson, Christine, Tron, Adriana E, Hyer, Marc L, Montoya, Megan, Mende, Abigail L, Nejo, Takahide, Downey, Kira M, Diebold, David, Lu, Min, Nicolay, Brandon, Okada, Hideho“…Prophylactic vaccination with the HLA-DR1-restricted IDH1(R132H) peptide or tumor-associated HLA-A2-restricted peptides did not enhance survival of tumor-bearing animals; however, vaccination with both HLA-A2-IDH1(R132H) and DR1-IDH1(R132H) peptides in combination with the IDH inhibitor significantly prolonged survival. …”
Publicado 2022
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259309por Leonard, Elizabeth, Kwinda, Zwannda, Baernighausen, Till, Dronavalli, Mithilesh, Adam, Maya, Pillay, Yogan“…Intervention – Amandla Mama mHealth videos, short 2D animated health promotional videos that promote healthy behavior in expectant mothers. …”
Publicado 2022
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259310por Shams, Morteza, Shamsi, Laya, Yousefi, Amirhosein, Sadrebazzaz, Alireza, Asghari, Ali, Mohammadi-Ghalehbin, Behnam, Shahabi, Saeed, Hatam, Gholamreza“…BACKGROUND: Blastocystis is a common intestinal protozoa found in animal and human fecal samples, with over 1 billion individuals infected worldwide. …”
Publicado 2022
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259311por Münzker, Julia, Haase, Nadine, Till, Andreas, Sucher, Robert, Haange, Sven-Bastiaan, Nemetschke, Linda, Gnad, Thorsten, Jäger, Elisabeth, Chen, Jiesi, Riede, Sjaak J., Chakaroun, Rima, Massier, Lucas, Kovacs, Peter, Ost, Mario, Rolle-Kampczyk, Ulrike, Jehmlich, Nico, Weiner, Juliane, Heiker, John T., Klöting, Nora, Seeger, Gudrun, Morawski, Markus, Keitel, Verena, Pfeifer, Alexander, von Bergen, Martin, Heeren, Joerg, Krügel, Ute, Fenske, Wiebke K.“…RYGB) or the repeated fecal microbiota transfer (FMT) from RYGB donors into DIO (diet-induced obesity) animals induces shifts in the intestinal microbiome, an effect that can be impaired by oral application of antibiotics (ABx). …”
Publicado 2022
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259312por Itson-Zoske, Brandon, Shin, Seung Min, Xu, Hao, Qiu, Chensheng, Fan, Fan, Hogan, Quinn H., Yu, Hongwei“…Whole-cell current-clamp recordings showed that AAV-mediated Ca(V)3.2iPA2 expression normalized hyperexcitability of the PSNs dissociated from the DRG of MIA animals, suggesting that Ca(V)3.2iPA2 attenuated pain behavior by reversing MIA-induced neuronal hyperexcitability. …”
Publicado 2022
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259313por Zhao, Lan, Wang, Jianshuo, Wang, Pengzhen, Deng, Zhanyu, Cui, Jin, Huang, Weiguang, Zhang, Shaoheng“…Although transplantation of cMSCs alone did not improve LV remodeling and function, cMSCs co-transfected with c-Myc and Oct4 promoted a more positive effect in their survival and reparative properties, increased animal survival, reduced infarct size, decreased scar thickness, inhibited LV remodeling, and improved heart function 30 days after MI. …”
Publicado 2022
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259314por Wen, Jingyuan, Huang, Zhao, Wei, Yi, Xue, Lin, Wang, Yufei, Liao, Jingyu, Liang, Junnan, Chen, Xiaoping, Chu, Liang, Zhang, Bixiang“…Subcutaneous xenograft and lung metastatic animal experiments were conducted to verify the role of hsa-miR-27b in HCC in vivo. …”
Publicado 2022
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259315por Doan, Dung Anh, Ho, Huong Hien, Tran, Long Duc, Nguyen, Phuong Lan, Le, Anh Thi Lan, Dinh, Dai Xuan“…Regarding the COVID-19 knowledge, the proportions of students who knew that mosquito bites and exposure to/eating wild animals would not lead to COVID-19 infection were not high (47.22 and 34.34%, respectively). …”
Publicado 2022
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259316por Patil, V., Hernandez-Franco, J. F., Yadagiri, G., Bugybayeva, D., Dolatyabi, S., Feliciano-Ruiz, N., Schrock, J., Hanson, J., Ngunjiri, J., HogenEsch, H., Renukaradhya, G. J.“…Specific pathogen free (SPF) pigs were vaccinated twice via intramuscular (IM) or intradermal (ID) routes and challenged with a virulent heterologous SwIAV H1N1-OH7 virus. RESULTS: Animals vaccinated IM or ID with NanoS100-SwIAV had significantly increased cross-reactive IgG and IgA titers in serum, nasal secretion and bronchoalveolar lavage fluid at day post challenge 6 (DPC6). …”
Publicado 2022
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259317por Ge, Jieyun, Wang, Qiubo, Chen, Gangcheng, Kassegne, Kokouvi, Zhang, Hangye, Yu, Jiali, Tang, Jianxia, Wang, Bo, Lu, Feng, Cao, Jun, Han, Eun-Taek, Cheng, Yang“…However, the genetic diversity of the RAMA gene in isolates of P. vivax (pvrama) and the immunogenicity of PvRAMA in animals remain unclear. METHODS: Genomic DNA was extracted from blood samples (n = 25) of patients in Jiangsu Province, China with imported infections of P. vivax from endemic countries in South and Southeast Asia. …”
Publicado 2022
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259318por Soumare, Harouna M., Dabira, Edgard Diniba, Camara, Muhammed M., Jadama, Lamin, Gaye, Pa Modou, Kanteh, Sainey, Jawara, Ebrima A., Njie, Amie Kolleh, Sanneh, Fatou, Ndiath, Mamadou Ousman, Lindsay, Steven W., Conteh, Bakary, Ceesay, Sainey, Mohammed, Nuredin, Ooko, Michael, Bradley, John, Drakeley, Chris, Erhart, Annette, Bousema, Teun, D’Alessandro, Umberto“…Mosquitoes die after feeding on humans or animals treated with ivermectin (IVM). Mass drug administration (MDA) with IVM could reduce vector survival and decrease malaria transmission. …”
Publicado 2022
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259319por Kong, Xiu mei, Song, Dan, Li, Jie, Jiang, Yi, Zhang, Xiao ying, Wu, Xiao Jun, Ge, Ming juan, Xu, Jiao jiao, Gao, Xiao min, Zhao, Qin“…The critical targets were TNF, Jun proto-oncogene (JUN), tumor protein p53 (TP53), and threonine kinase 1 (AKT1). Animal experiments showed that the ethyl acetate extraction of G.s Maxim ameliorated the hypoxia-induced damage of hippocampal nerve cells in the CA1 region and reversed elevated serum expression of TNF-α, IL-6, and NF-κ B in hypoxic rats. …”
Publicado 2022
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259320por Kim, Sung-Hee, Kim, Jiseon, Jang, Ji Yun, Noh, Hyuna, Park, Jisun, Jeong, Haengdueng, Jeon, Donghun, Uhm, Chanyang, Oh, Heeju, Cho, Kyungrae, Jeon, Yoon, On, Dain, Yoon, Suhyeon, Lim, Soo-Yeon, Kim, Sol Pin, Lee, Youn Woo, Jang, Hui Jeong, Park, In Ho, Oh, Jooyeon, Seo, Jung Seon, Kim, Jeong Jin, Seok, Sang-Hyuk, Lee, Yu Jin, Hong, Seung-Min, An, Se-Hee, Kim, Seo Yeon, Kim, Young Been, Hwang, Ji-Yeon, Lee, Hyo-Jung, Kim, Hong Bin, Choi, Kang-Seuk, Park, Jun Won, Seo, Jun-Young, Yun, Jun-Won, Shin, Jeon-Soo, Lee, Ho-Young, Kim, Kyoungmi, Lee, Daekee, Lee, Ho, Nam, Ki Taek, Seong, Je Kyung“…However, ACE2 does not react to SARS-CoV-2 in inbred wild-type mice, which poses a challenge for preclinical research with animal models, necessitating a human ACE2 (hACE2)-expressing transgenic mouse model. …”
Publicado 2022
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