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  1. 4501
    “…The hearts of transgenic mice revealed higher content of Galectin-3. Conclusion: This animal model and associated features observed as result of cardiac TTR deposition provide a promising and invaluable research tool for a better understanding of the implicated pathways that lead to the lethality associated to TTR cardiac amyloidosis. …”
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    Cellular environment of TTR deposits in an animal model of ATTR—Cardiomyopathy
  2. 4502
    “…The availability of high-fidelity animal models for oncology research has grown enormously in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment of cancer to be undertaken. …”
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    Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials
  3. 4503
    “…This technique has widely been applied to section mineralized small animal (i.e., mice, rat, rabbit) specimens, but has only been sparsely implemented for large animal samples that have a greater tendency to tear due to their increased surface area. …”
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    Multiplexed tape-stabilized cryohistology of mineralized large animal specimens
  4. 4504
    “…SIMPLE SUMMARY: The role of the social determinants of health (i.e., physical, social and economic factors affecting human health) and their impact on companion animal welfare have not been fully explored. Through a social determinants lens, it is possible to improve the understanding of companion animal guardian challenges in managing their companion animal’s welfare needs. …”
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    The Impact of the Social Determinants of Human Health on Companion Animal Welfare
  5. 4505
    por Liu, Sufang, Crawford, Joshua, Tao, Feng
    Publicado 2023
    “…Orofacial pain refers to pain occurring in the head and face, which is highly prevalent and represents a challenge to clinicians, but its underlying mechanisms are not fully understood, and more studies using animal models are urgently needed. Currently, there are different assessment methods for analyzing orofacial pain behaviors in animal models. …”
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    Assessing Orofacial Pain Behaviors in Animal Models: A Review
  6. 4506
    por Yadav, Kush Kumar, Kenney, Scott P.
    Publicado 2023
    “…Some of the greatest discoveries regarding HEV have come from using animal models for which naturally occurring strains of HEV have been identified, including pigs and chickens, but key limitations have made animal models imperfect for studying all aspects of human HEV infections. …”
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    Animal Models for Studying Congenital Transmission of Hepatitis E Virus
  7. 4507
    “…There is growing evidence of interspecies transmission including infection of domestic animals and widespread circulation in wildlife. However, knowledge of SARS-CoV-2 stability in animal biological fluids and their role in transmission is still limited as previous studies focused on human biological fluids. …”
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    Stability of SARS-CoV-2 in Biological Fluids of Animals
  8. 4508
    “…For veterinary regenerative medicine to have impact, either for human medicine and/or for domesticated animals, answering these questions is pivotal.…”
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    Companion animal organoid technology to advance veterinary regenerative medicine
  9. 4509
    por Ewe, Chee Kiang, Rechavi, Oded
    Publicado 2023
    “…Here, we discuss three major barriers to TEI in animals, two of which, the “Weismann barrier” and germline epigenetic reprogramming, have been known for decades. …”
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    The third barrier to transgenerational inheritance in animals: somatic epigenetic resetting
  10. 4510
    “…The animals' survival after infection, parasite migration in the animals and pathological damage to the liver were observed. …”
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    Exploration of animal models to study the life cycle of Fasciola hepatica
  11. 4511
    “…Citizen science is filling important monitoring gaps and thus contributing to the conservation of rare or threatened animals. However, most researchers have used peer‐reviewed publications to evaluate citizen science contributions. …”
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    Scientific contributions of citizen science applied to rare or threatened animals
  12. 4512
    “…SIMPLE SUMMARY: The present review highlights and examines the importance of animal models in relevant topics concerning current human and animal health. …”
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    The Importance of Animal Models in Biomedical Research: Current Insights and Applications
  13. 4513
    “…Having empathy for others is typically generalized to having empathy for animals. However, empathy for humans and for animals are only weakly correlated. …”
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    Exploring narcissism and human- and animal-centered empathy in pet owners
  14. 4514
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    Biological Effects of Black Phosphorus Nanomaterials on Mammalian Cells and Animals
  15. 4515
    “…Sexual behavior in animals is important in ensuring the continuity of the generation. …”
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    A neuroscience-based approach to the assessment of sexual behavior in animals
  16. 4516
    “…Movement is critical to animal survival and, thus, biodiversity in fragmented landscapes. …”
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    The travel speeds of large animals are limited by their heat-dissipation capacities
  17. 4517
    “…This review gives an overview of MS animal models, focusing on the current imaging modalities at the microscopic and macroscopic levels and emphasizing the importance of multimodal approaches to improve our understanding of the disease and minimize the use of animals. …”
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    Contribution of Intravital Neuroimaging to Study Animal Models of Multiple Sclerosis
  18. 4518
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    Erratum: The problem and promise of scale in multilayer animal social networks
  19. 4519
    “…Here we report on a study in a large animal model of right heart failure caused by severe tricuspid regurgitation comparing cardiovascular and lymphatic findings in a group of animals that did not develop ascites with a group of animals that developed ascites. …”
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    Ascites in Animals With Right Heart Failure: Correlation With Lymphatic Dysfunction
  20. 4520
    “…It is important to understand the distribution of antimicrobial-resistant bacteria and their drug-resistant genes in animals. Previous review articles mostly focused on a single bacterium or a single animal. …”
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    Extended-Spectrum β-Lactamases (ESBL) Producing Bacteria in Animals
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