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4741
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4742“…CONCLUSIONS: The DPP domain of DSPP was found to change dramatically within mammals and was lost in two truly toothless animals. The defining aspect of DPP, the long repeating phosphorylation domain, apparently undergoes frequent slip replication and recombination events that rapidly change specific patterns but not its overall biochemical character in toothed animals. …”
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4743
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4744por Nabe-Nielsen, Jacob, Sibly, Richard M., Forchhammer, Mads C., Forbes, Valery E., Topping, Christopher J.“…To circumvent this problem we used individual-based models (IBMs) of interacting animals in experimental modifications of a real Danish landscape. …”
Publicado 2010
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4745“…The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human Aβ precursor protein (APP) and/or some of the enzymes implicated in their metabolic processing. …”
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4746por van der Worp, H. Bart, Howells, David W., Sena, Emily S., Porritt, Michelle J., Rewell, Sarah, O'Collins, Victoria, Macleod, Malcolm R.“…Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.…”
Publicado 2010
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4747por Clark, Jeremy J., Sandberg, Stefan G., Wanat, Matthew J., Gan, Jerylin O., Horne, Eric A., Hart, Andrew S., Akers, Christina A., Parker, Jones G., Willuhn, Ingo, Martinez, Vicente, Evans, Scott B., Stella, Nephi, Phillips, Paul E. M.Enlace del recurso
Publicado 2009
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4748“…The MAT-sf consists of 10 animated video clips that assess respondents’ level of proficiency in performing each task. …”
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4749
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4750por van Loo, Inge, Huijsdens, Xander, Tiemersma, Edine, de Neeling, Albert, van de Sande-Bruinsma, Nienke, Beaujean, Desiree, Voss, Andreas, Kluytmans, Jan“…This study shows that MRSA from an animal reservoir has recently entered the human population and is now responsible for >20% of all MRSA in the Netherlands.…”
Publicado 2007
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4751“…A growing number of studies of auditory processing are being carried out in awake, behaving animals, creating a need for precisely controlled sound delivery without restricting head movements. …”
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4752
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4753
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4754por Mounsey, Kate, Ho, Mei-Fong, Kelly, Andrew, Willis, Charlene, Pasay, Cielo, Kemp, David J., McCarthy, James S., Fischer, Katja“…To increase intensity and duration of infestation without generating animal welfare issues we have optimised an immunosuppression regimen utilising daily oral treatment with 0.2mg/kg dexamethasone. …”
Publicado 2010
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4755“…These artificial boundaries might bias the results of animal dispersal models by creating artificial barriers to movement for model organisms where there are no barriers for real organisms. …”
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4756por Golestani, Reza, Wu, Chao, Tio, René A., Zeebregts, Clark J., Petrov, Artiom D., Beekman, Freek J., Dierckx, Rudi A. J. O., Boersma, Hendrikus H., Slart, Riemer H. J. A.“…We give examples on how diagnostic tracers, new therapeutic interventions, pre- and postcardiovascular event prognosis, and functional and pathophysiological heart conditions can be explored by microSPECT, using small-animal models of cardiovascular disease.…”
Publicado 2010
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4757por O’Sullivan, Laurie, Murphy, Brian, McLoughlin, Peter, Duggan, Patrick, Lawlor, Peadar G., Hughes, Helen, Gardiner, Gillian E.“…Their potential for use as prebiotics for both humans and animals will be highlighted by reviewing data from both in vitro and in vivo studies conducted to date.…”
Publicado 2010
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4758por Vandeputte, Caroline, Taymans, Jean-Marc, Casteels, Cindy, Coun, Frea, Ni , Yicheng, Van Laere, Koen, Baekelandt, Veerle“…BACKGROUND: Accurate and reproducible behavioral tests in animal models are of major importance in the development and evaluation of new therapies for central nervous system disease. …”
Publicado 2010
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4759
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4760“…The amyloid-beta (Aβ) hypothesis of Alzheimer's disease (AD) causality is now well into its third decade and is finally entering a phase of rigorous clinical testing in numerous late stage clinical trials. The use of Aβ-based animal models of AD has been essential to the discovery and/or preclinical validation of many of these therapeutic approaches. …”
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