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  1. 4841
    por Holló, Gábor, Novák, Mihály
    Publicado 2012
    “…This confers an obvious selective advantage on the bilateral animal. IMPLICATIONS OF THE HYPOTHESIS: These considerations imply the view that animal evolution is a highly channelled process, in which bilateral and radial body symmetries seem to be inevitable. …”
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    The manoeuvrability hypothesis to explain the maintenance of bilateral symmetry in animal evolution
  2. 4842
    “…BACKGROUND: Physiology of the exocrine pancreas has been well studied in domestic and in laboratory animals as well as in humans. However, it remains quite unknown in wildlife mammals. …”
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    Is there adaptation of the exocrine pancreas in wild animal? The case of the Roe Deer
  3. 4843
    “…Episodic memory, especially memory for contextual or spatial information, is particularly vulnerable to age-related decline in humans and animal models of aging. The continuing improvement of virtual environment technology for testing humans signifies that widely used procedures employed in the animal literature for examining spatial memory could be developed for examining age-related cognitive decline in humans. …”
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    Characterizing cognitive aging of spatial and contextual memory in animal models
  4. 4844
    por Tfelt-Hansen, Peer Carsten
    Publicado 2009
    “…Sumatriptan, a relatively hydrophilic triptan, based on several animal studies has been regarded to be unable to cross the blood–brain barrier (BBB). …”
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    Does sumatriptan cross the blood–brain barrier in animals and man?
  5. 4845
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    Evolution of the PWWP-domain encoding genes in the plant and animal lineages
  6. 4846
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    Animal models of human nutritional diseases: a short overview
  7. 4847
    “…In this review, we examine some of the gene delivery approaches used to treat animal models of autosomal dominant retinitis pigmentosa, focusing on those models associated with mutations in the gene for rhodopsin. …”
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    Gene therapy in animal models of autosomal dominant retinitis pigmentosa
  8. 4848
    “…CONCLUSIONS—: Circulating T(EM) cells are associated with increased atherosclerosis and coronary artery disease in humans and in animal models and could represent a key CD4(+)T-cell subset related to the atherosclerotic process. …”
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    Effector Memory T cells Are Associated With Atherosclerosis in Humans and Animal Models
  9. 4849
    “…The analysis of loss- and gain-of-function mutant animals revealed that this factor plays a crucial role in the endocrine pancreas. …”
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    Generation of animals allowing the conditional inactivation of the Pax4 gene
  10. 4850
    “…As discussed herein, understanding these differences and the novel properties of the toxins is imperative for clinical management decisions, design of appropriate animal models, and choices of adjunctive therapeutics. …”
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    Shiga Toxins and the Pathophysiology of Hemolytic Uremic Syndrome in Humans and Animals
  11. 4851
    “…A group of promising candidates of this category would be venom-toxins of animal origin of potential medicinal value. Traditional systems of medicine as well as folklores mention the use of venom-toxins for the treatment of various diseases. …”
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    Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential
  12. 4852
    “…The present study aimed to investigate the anti-inflammatory effect of Yanshu in xylene-induced ear edema in mice and carrageenan-induced paw edema in rats by measuring the degree of edema in the animal models. The histopathology and the levels of prostaglandin E2 (PGE2) and cycloxygenase-2 (COX-2) in the hind paws of the carrageenan-treated rats were also analyzed. …”
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    Anti-inflammatory activity of Yanshu spraying agent in animal models
  13. 4853
    “…Their ability to efficiently deliver transgenes to multi-lineage long-term repopulating cells in large animal models suggests they will be effective for several human hematopoietic diseases. …”
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    Large Animal Models for Foamy Virus Vector Gene Therapy
  14. 4854
    “…Furthermore, GRN-deficient animal models have been established and they are believed to be promising disease models as they show accelerated aging and recapitulate at least some neuropathological features of FTD. …”
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    Mechanisms of Granulin Deficiency: Lessons from Cellular and Animal Models
  15. 4855
    “…In this paper we will discuss the endogenous stem cell response to SCI in animal models. All SCI animal models experience a similar peak of cell proliferation three days after injury; however, each specific type of injury promotes a specific and distinct stem cell response. …”
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    Endogenous Proliferation after Spinal Cord Injury in Animal Models
  16. 4856
    “…Since the central serotonergic dysfunction is an important and well-known cause mediating the pathophysiology of trauma-related symptoms in PTSD, it is reasonable to predict that flavonoids may exert therapeutic effects on PTSD in animal models. Therefore, the present study aims to examine the effect of flavonoids in alleviating the enhanced anxiety and fear response induced in two PTSD animal models. …”
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    Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder
  17. 4857
    “…While it is clear that some human gut bacterial pathogens come from animals (showing that human – animal transmission occurs), the extent to which the usually non-pathogenic commensal taxa are shared between humans and animals has not been explored. …”
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    Comparison of the Distal Gut Microbiota from People and Animals in Africa
  18. 4858
    “…The One Health paradigm for global health recognizes that most new human infectious diseases will emerge from animal reservoirs. Little consideration has been given to the known and potential zoonotic infectious diseases of small companion animals. …”
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    Surveillance of Zoonotic Infectious Disease Transmitted by Small Companion Animals
  19. 4859
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    Retraction: progress of genome wide association study in domestic animals
  20. 4860
    “…Advances in molecular biotechnology have introduced new generations of molecular markers for use in the genetic improvement of farm animals. Consequently, more accurate genetic information can be obtained to better understand existing animal genetic resources. …”
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    Review on the development of genotyping methods for assessing farm animal diversity
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