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  1. 4961
    por Cekanova, Maria, Rathore, Kusum
    Publicado 2014
    “…Successful bench-to-bedside translation of basic scientific findings about cancer into therapeutic interventions for patients depends on the selection of appropriate animal experimental models. Cancer research uses animal and human cancer cell lines in vitro to study biochemical pathways in these cancer cells. …”
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    Animal models and therapeutic molecular targets of cancer: utility and limitations
  2. 4962
    “…Allergy to laboratory animals is a well known occupational hazard and remains a health concern for individuals in contact with lab animals. …”
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    Prevalence of Occupational Allergy in Medical Researchers Exposed to Laboratory Animals
  3. 4963
    “…A religious perspective concerning the use of animal and human derived drug ingredients has not thoroughly been investigated. …”
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    Animal derived products may conflict with religious patients’ beliefs
  4. 4964
    “…Here, we provide an overview of the main epigenetic mechanisms regulating gene expression and discuss fundamental epigenetic mechanisms and factors functioning in both plants and animals. Finally, we hypothesize that animal genome can be reprogrammed by epigenetic factors from the plant protoplast.…”
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    Unexplored Potentials of Epigenetic Mechanisms of Plants and Animals—Theoretical Considerations
  5. 4965
    “…BACKGROUND: The globalization of the food supply and the increased movements of people, animals and goods have increased the threat of Salmonella infections in several countries. …”
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    A meta-analysis of the prevalence of Salmonella in food animals in Ethiopia
  6. 4966
    por Zanella, Adroaldo Jose
    Publicado 2008
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    Meeting the educational challenges to engage veterinarians in animal welfare science
  7. 4967
    por Harwood, Catherine G., Rao, Reeta P.
    Publicado 2014
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    Host Pathogen Relations: Exploring Animal Models for Fungal Pathogens
  8. 4968
    por Takashima, Gregg K., Day, Michael J.
    Publicado 2014
    “…“One Health”, also called “One Medicine”, began as an initiative advocating greater integration of human and animal medicine, in the 1800s. This concept has recently come to prominence, driven by the recognition that 75% of the newly emerging infectious diseases will arise from animal reservoirs, and that successful control and prevention will require a coordinated human medical and veterinary approach. …”
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    Setting the One Health Agenda and the Human-Companion Animal Bond
  9. 4969
    “…Many studies utilizing dogs, cats, birds, fish, and robotic simulations of animals have tried to ascertain the health benefits of pet ownership or animal-assisted therapy in the elderly. …”
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    The Benefit of Pets and Animal-Assisted Therapy to the Health of Older Individuals
  10. 4970
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    Use of animal models for exome prioritization of rare disease genes
  11. 4971
    “…The encouraging outcomes obtained in companion animals support their ready application in veterinary clinical oncology and serve as preclinical proof of concept and safety assay for future human gene therapy trials.…”
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    Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals
  12. 4972
    “…Since metastasis arises through complex steps, a suitable animal model is indispensable for investigation of metastasis. …”
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    Correlation between Plasma DNA and Tumor Status in an Animal Model
  13. 4973
    “…CONCLUSION: Our findings indicate that vardenafil and pentoxifylline are effective treatment options in an animal model of ischemic colitis. The positive clinical effects produced by these drugs are likely due to their influence on the hemodynamics associated with vascular smooth muscle and platelet functions.…”
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    The effects of vardenafil and pentoxifylline administration in an animal model of ischemic colitis
  14. 4974
    “…The responses of the ferrets implied both long- and short-term criterion dynamics. The animals exhibited a bias in favour of responding “yes” during blocks of harder trials, and vice versa. …”
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    Decision Criterion Dynamics in Animals Performing an Auditory Detection Task
  15. 4975
    por Asakura, Hidesaku
    Publicado 2014
    “…DIC with balanced fibrinolysis is a DIC type usually seen in solid tumors, with an intermediate pathogenesis between the above two types. In animal DIC models, lipopolysaccharide (LPS)-induced models are similar to suppressed-fibrinolytic-type DIC, whereas tissue factor (TF)-induced models are similar to enhanced fibrinolytic/balanced fibrinolytic DIC. …”
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    Classifying types of disseminated intravascular coagulation: clinical and animal models
  16. 4976
    por Margine, Irina, Krammer, Florian
    Publicado 2014
    “…Though the first influenza vaccine preparation was licensed more than 60 years ago, current research efforts seek to develop novel vaccination strategies with improved immunogenicity, effectiveness, and breadth of protection. Animal models of influenza have been essential in facilitating studies aimed at understanding viral factors that affect pathogenesis and contribute to disease or transmission. …”
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    Animal Models for Influenza Viruses: Implications for Universal Vaccine Development
  17. 4977
    “…In addition, we investigated the effects of PG and PQ in our animal models in high and low temperature environments. …”
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    The Effects of Panax ginseng and Panax quinquefolius on Thermoregulation in Animal Models
  18. 4978
    “…A novel animal experiment with different administration times, based on the mice oestrous cycle, for primary dysmenorrhoea treatment was explored in this study. …”
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    Animal Study on Primary Dysmenorrhoea Treatment at Different Administration Times
  19. 4979
    “…The applied procedures were induction of MS by fructose in drinking water; experimental protocol of walking and running; weighing of body mass and VAT; sacrifice of animals with blood collection and removal of organs and processing of samples for light microscopy using the analysis of volume densities (Vv) of the studied structures. …”
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    Effect of different exercise intensities on the pancreas of animals with metabolic syndrome
  20. 4980
    por Sivrikaya, G. Ulufer
    Publicado 2011
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    Intrathecal Injection of Amitriptyline and Doxepin for Spinal Anesthesia in Animal Studies
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