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5381por Harding, Harry R, Gordon, Timothy A C, Eastcott, Emma, Simpson, Stephen D, Radford, Andrew N“…Anthropogenic noise is a recognized global pollutant, affecting a wide range of nonhuman animals. However, most research considers only whether noise pollution has an impact, ignoring that individuals within a species or population exhibit substantial variation in responses to stress. …”
Publicado 2019
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5382por Bikou, Olympia, Tharakan, Serena, Yamada, Kelly P., Kariya, Taro, Gordon, Alexandra, Miyashita, Satoshi, Watanabe, Shin, Sassi, Yassine, Fish, Kenneth, Ishikawa, Kiyotake“…Surviving animals underwent functional and morphological characterization at 1-week post-procedure. …”
Publicado 2019
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5383por Ravignani, Andrea, Dalla Bella, Simone, Falk, Simone, Kello, Christopher T., Noriega, Florencia, Kotz, Sonja A.“…We review the literature on rhythm in speech and animal vocalizations as a first step toward understanding similarities and differences across species. …”
Publicado 2019
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5384por More, Simon J.“…The aim of this paper is to present scientific perspectives from the science-policy interface in animal health and welfare, with an emphasis on factors critical to scientific effectiveness. …”
Publicado 2019
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5385por Deerhake, M. Elizabeth, Biswas, Debolina D., Barclay, William E., Shinohara, Mari L.“…Accumulating evidence has identified both pathogenic and protective functions of PRR signaling in MS and its animal model, experimental autoimmune encephalomyelitis (EAE). …”
Publicado 2019
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5386por Zamperin, Gianpiero, Lucas, Pierrick, Cano, Irene, Ryder, David, Abbadi, Miriam, Stone, David, Cuenca, Argelia, Vigouroux, Estelle, Blanchard, Yannick, Panzarin, ValentinaEnlace del recurso
Publicado 2019
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5387por Petersen, Jillian M., Kemper, Anna, Gruber-Vodicka, Harald, Cardini, Ulisse, van der Geest, Matthijs, Kleiner, Manuel, Bulgheresi, Silvia, Mußmann, Marc, Herbold, Craig, Seah, Brandon K.B., Antony, Chakkiath Paul, Liu, Dan, Belitz, Alexandra, Weber, Miriam“…Chemosynthetic symbioses are partnerships between invertebrate animals and chemosynthetic bacteria. The latter are the primary producers, providing most of the organic carbon needed for the animal host's nutrition. …”
Publicado 2016
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5388por Campbell, Stefanie B., Nelson, Christina A., Hinckley, Alison F., Kugeler, Kiersten J.“…Since 1970, >50% of patients with plague in the United States had interactions with animals that might have led to infection. Among patients with pneumonic plague, nearly all had animal exposure. …”
Publicado 2019
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5389por Surcel, Mihaela, Munteanu, Adriana Narcisa, Huică, Radu-Ionuț, Isvoranu, Gheorghița, Pîrvu, Ioana Ruxandra, Constantin, Carolina, Bratu, Ovidiu, Căruntu, Constantin, Zaharescu, Isadora, Sima, Lucica, Costache, Marieta, Neagu, MonicaEnlace del recurso
Publicado 2019
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5390“…Quantification of frailty with both “frailty phenotype” and “frailty index” approaches has begun to highlight putative frailty mechanisms and new animal models of frailty are inspiring preclinical research. …”
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5391“…Wild animals are brought into captivity for many reasons—conservation, research, agriculture and the exotic pet trade. …”
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5392por Chawengsaksophak, Kallayanee“…This review will address how animal models have refined our understanding of the role of Cdx2 in these common human cancers.…”
Publicado 2019
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5393
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5394“…These sometimes employ custom genetic interventions such as antisense-mediated exon skipping or genome editing, aiming to restore protein function in a mutation-specific manner. Animal models can facilitate the development of personalized medicine approaches; however, given that they target human mutations and therefore human genetic sequences, scientists rely on the availability of humanized animal models. …”
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5395“…To improve validity, scientists must collaborate closely with the animal facility involved as soon as the decision to use animals has been made. …”
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5396“…This short review summarizes LCB biosynthesis with their associating metabolic pathways in animals, plants and fungi.…”
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5397por Seekatz, Anna M.Enlace del recurso
Publicado 2019
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5398por Michels, Monique, Abatti, Mariane Rocha, Ávila, Pricila, Vieira, Andriele, Borges, Heloisa, Carvalho Junior, Celso, Wendhausen, Diogo, Gasparotto, Juciano, Tiefensee Ribeiro, Camila, Moreira, José Claudio Fonseca, Gelain, Daniel Pens, Dal‐Pizzol, Felipe“…Rats were subjected to CLP, and some animals were treated with minocycline (10 ug/kg) by i.c.v. administration. …”
Publicado 2019
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5399por Foissac, Sylvain, Djebali, Sarah, Munyard, Kylie, Vialaneix, Nathalie, Rau, Andrea, Muret, Kevin, Esquerré, Diane, Zytnicki, Matthias, Derrien, Thomas, Bardou, Philippe, Blanc, Fany, Cabau, Cédric, Crisci, Elisa, Dhorne-Pollet, Sophie, Drouet, Françoise, Faraut, Thomas, Gonzalez, Ignacio, Goubil, Adeline, Lacroix-Lamandé, Sonia, Laurent, Fabrice, Marthey, Sylvain, Marti-Marimon, Maria, Momal-Leisenring, Raphaelle, Mompart, Florence, Quéré, Pascale, Robelin, David, Cristobal, Magali San, Tosser-Klopp, Gwenola, Vincent-Naulleau, Silvia, Fabre, Stéphane, der Laan, Marie-Hélène Pinard-Van, Klopp, Christophe, Tixier-Boichard, Michèle, Acloque, Hervé, Lagarrigue, Sandrine, Giuffra, Elisabetta“…BACKGROUND: Comparative genomics studies are central in identifying the coding and non-coding elements associated with complex traits, and the functional annotation of genomes is a critical step to decipher the genotype-to-phenotype relationships in livestock animals. As part of the Functional Annotation of Animal Genomes (FAANG) action, the FR-AgENCODE project aimed to create reference functional maps of domesticated animals by profiling the landscape of transcription (RNA-seq), chromatin accessibility (ATAC-seq) and conformation (Hi-C) in species representing ruminants (cattle, goat), monogastrics (pig) and birds (chicken), using three target samples related to metabolism (liver) and immunity (CD4+ and CD8+ T cells). …”
Publicado 2019
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5400“…Without field efficacy studies, researchers must rely on animal models of MARV infection to assess the efficacy of vaccines and treatments, with the limitations being the accuracy of the animal model in recapitulating human pathogenesis. …”
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