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7121“…The findings are contrasted with seminal studies in human infants that motivated the work in nonhuman animals. This synopsis identifies advances in knowledge and where uncertainty remains regarding the various strategies that nonhuman animals can adopt for processing sequencing dependencies. …”
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7122por De Gioia, Roberta, Citterio, Gaia, Abati, Elena, Nizzardo, Monica, Bresolin, Nereo, Comi, Giacomo Pietro, Corti, Stefania, Rizzo, Federica“…The identification of mutations in MFN2 has allowed the generation of diverse transgenic animal models, but to date, their ability to recapitulate the CMT2A phenotype is limited, precluding elucidation of its pathogenesis and discovery of therapeutic strategies. …”
Publicado 2020
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7123por Akkermans, Arnoud, Chapsal, Jean-Michel, Coccia, Eliana M., Depraetere, Hilde, Dierick, Jean-François, Duangkhae, Parichat, Goel, Sunil, Halder, Marlies, Hendriksen, Coenraad, Levis, Robin, Pinyosukhee, Koraphong, Pullirsch, Dieter, Sanyal, Gautam, Shi, Li, Sitrin, Robert, Smith, Dean, Stickings, Paul, Terao, Eriko, Uhlrich, Sylvie, Viviani, Laura, Webster, Jim“…It is critical for global vaccine community to work together to secure effective progress towards animal welfare and to ensure that vaccines of ever higher quality can reach the populations in need in the shortest possible timeframe. …”
Publicado 2020
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7124
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7125“…This article reviews the clinical, epidemiologic, virologic, and pathologic characteristics of nine important coronaviruses of companion animals.…”
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7126por Deane, Colleen S, Bass, Joseph J, Crossland, Hannah, Phillips, Bethan E, Atherton, Philip J“…This is despite the lower anabolic profile of plant and collagen protein due to the inferior essential amino acid profile (e.g., lower leucine content) and subordinate digestibility (versus animal). This review evaluates the efficacy of animal-, plant- and collagen-derived proteins in isolation, and as protein blends, for augmenting muscle and bone metabolism and health in the context of ageing, exercise and energy restriction.…”
Publicado 2020
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7127“…However, despite correct host/graft coupling, most animal studies demonstrate an arrhythmogenicity of the engrafted tissue and variable survival. …”
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7128por Bergmeister, Konstantin D., Aman, Martin, Kramer, Anne, Schenck, Thilo L., Riedl, Otto, Daeschler, Simeon C., Aszmann, Oskar C., Bergmeister, Helga, Golriz, Mohammad, Mehrabi, Arianeb, Hundeshagen, Gabriel, Enkhbaatar, Perenlei, Kinsky, Michael P., Podesser, Bruno K.“…We hypothesize that supplemental simulations in animal models provide a realistic training to augment clinical experiences. …”
Publicado 2020
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7129por Derbyshire, Emma J.“…Given this, shifts from animal to plant food protein are gaining momentum and are an important part of reducing carbon emissions and consumptive water use. …”
Publicado 2020
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7130por Roller, Marco, Hansen, Sören, Böhlken-Fascher, Susanne, Knauf-Witzens, Tobias, Czerny, Claus-Peter, Goethe, Ralph, Abd El Wahed, Ahmed“…Despite many reports in animals kept in zoological gardens, systemic surveillance has rarely been reported. …”
Publicado 2020
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7131“…However, there has been conflicting data regarding the specific role of MCs in scar formation in both animal and human studies. Whilst animal studies have proved to be valuable in studying the MC phenomenon in wound healing, the appropriate translation of these findings to cutaneous wound healing and scar formation in human subjects remains crucial to elucidate the role of these cells and target treatment effectively. …”
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7132por Timofeev, Vitalii, Titareva, Galina, Bahtejeva, Irina, Kombarova, Tatiana, Kravchenko, Tatiana, Mokrievich, Alexander, Dyatlov, Ivan“…In the present article, we evaluated the comparative virulence of subsp. mediasiatica in vaccinated laboratory animals which we infected with virulent strains: subsp. mediasiatica 678, subsp. holarctica 503, and subsp. tularensis SCHU within 60 to 180 days after vaccination. …”
Publicado 2020
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7133por Boonyasuppayakorn, Siwaporn, Saelee, Thanaphon, Visitchanakun, Peerapat, Leelahavanichkul, Asada, Hengphasatporn, Kowit, Shigeta, Yasuteru, Huynh, Thao Nguyen Thanh, Chu, Justin Jang Hann, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn“…Here, we chemically modified flavanones, pinocembrin and pinostrobin, by halogenation and characterized them as potential dengue 2 inhibitors and performed toxicity tests in human-derived cells and in vivo animal model. Dibromopinocembrin and dibromopinostrobin inhibited dengue serotype 2 at the EC(50)s of 2.0640 ± 0.7537 and 5.8567 ± 0.5074 µM with at the CC(50)s of 67.2082 ± 0.9731 and >100 µM, respectively. …”
Publicado 2020
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7134por Maekawa, Takuya, Ohara, Kazuya, Zhang, Yizhe, Fukutomi, Matasaburo, Matsumoto, Sakiko, Matsumura, Kentarou, Shidara, Hisashi, Yamazaki, Shuhei J., Fujisawa, Ryusuke, Ide, Kaoru, Nagaya, Naohisa, Yamazaki, Koji, Koike, Shinsuke, Miyatake, Takahisa, Kimura, Koutarou D., Ogawa, Hiroto, Takahashi, Susumu, Yoda, Ken“…A comparative analysis of animal behavior (e.g., male vs. female groups) has been widely used to elucidate behavior specific to one group since pre-Darwinian times. …”
Publicado 2020
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7135por Bryk, Marta, Chwastek, Jakub, Kostrzewa, Magdalena, Mlost, Jakub, Pędracka, Aleksandra, Starowicz, Katarzyna“…Animals were sacrificed on day 2, 7, 14, 21, 28 after injection and lumbar spinal cord, cartilage and synovium were collected. …”
Publicado 2020
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7136por Kringe, Leona, Sena, Emily S, Motschall, Edith, Bahor, Zsanett, Wang, Qianying, Herrmann, Andrea M, Mülling, Christoph, Meckel, Stephan, Boltze, Johannes“…Our analysis revealed that large animal models are utilized with similar shortcomings as small animal models. …”
Publicado 2020
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7137The Effects of Tannins in Monogastric Animals with Special Reference to Alternative Feed Ingredientspor Hassan, Zahra Mohammed, Manyelo, Tlou Grace, Selaledi, Letlhogonolo, Mabelebele, Monnye“…Over recent years, the monogastric animal industry has witnessed an increase in feed prices due to several factors, and this trend is likely to continue. …”
Publicado 2020
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7138por Tsai, Arthur C., Huang, Andrew Chih Wei, Yu, Ying Hao, Kuo, Chii-Shyang, Hsu, Chih-Chan, Lim, Yeou San, Shyu, Bai Chuang“…The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. …”
Publicado 2020
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7139por Begni, Veronica, Sanson, Alice, Pfeiffer, Natascha, Brandwein, Christiane, Inta, Dragos, Talbot, Steven R., Riva, Marco Andrea, Gass, Peter, Mallien, Anne Stephanie“…Since social isolation models severe psychiatric symptoms, it is to be expected that it affects the overall wellbeing of the animals. As also promoted by the 3Rs principle, though, it is pivotal to decrease the burden of laboratory animals by limiting the number of subjects (reduce, replace) and by improving the animals’ wellbeing (refine). …”
Publicado 2020
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7140