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1241“…In many countries, local Animal Ethics Committees are established to ensure that animals are treated in accordance with 3Rs (Replace, Reduce, Refine) principles. …”
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1242“…Discussions of this Nozickian Hybrid View, and similar approaches to animal ethics, often assume that such an approach reflects the commonsense view, and best captures common moral intuitions. …”
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1245“…Finally, we highlight studies indicating that experimental overfeeding can be employed to study the transgenerational effects of a positive energy balance and how dietary composition and macronutrient content might impact energy homeostasis and obesity development in animals. MAJOR CONCLUSIONS: Experimental overfeeding of animals is a powerful yet underappreciated method to investigate the defense mechanisms against weight gain. …”
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1246por Miziara, Ivan Dieb, de Matos Magalhães, Ana Tereza, Santos, Maruska d'Aparecida, Gomes, Érika Ferreira, de Oliveira, Reinaldo Ayer“…The use of animals in scientific experiments has beendescribed since the fifth century BC. …”
Publicado 2015
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1249“…SIMPLE SUMMARY: Plant feed additives have been used in animal diets for improving animal health and welfare. …”
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1250por Werner, Erik“…Molecular animations play an increasing role in scientific visualisation and science communication. …”
Publicado 2022
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1254por Svenson, Karen L., Krasinski, Stephen D., Ellis, Michael, Rosenthal, Nadia, Liu, Edison T., Fasman, Kenneth H.“…In 2021, the National Institutes of Health Advisory Committee to the Director (ACD) announced recommendations to improve the reproducibility of biomedical research using animals. In response, The Jackson Laboratory faculty and institutional leaders identified key strategies to further address this important issue. …”
Publicado 2022
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1255“…According to these data, germ granules are involved in the determination of germline cells in some animals, such as Amphibia. In other animals, such as Mammalia, germ granules are involved in the processes of transposons inactivation and sequestration of mRNA and proteins to temporarily decrease their activity. …”
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1257por Galaburda, Albert M.“…As some critics have stated, the term “developmental dyslexia” refers to a strictly human disorder, relating to a strictly human capacity – reading – so it cannot be modeled in experimental animals, much less so in lowly rodents. However, two endophenotypes associated with developmental dyslexia are eminently suitable for animal modeling: Cerebral Lateralization, as illustrated by the association between dyslexia and non-righthandedness, and Cerebrocortical Dysfunction, as illustrated by the described abnormal structural anatomy and/or physiology and functional imaging of the dyslexic cerebral cortex. …”
Publicado 2022
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1258“…One of the primary concerns in animal research is ensuring the welfare of laboratory animals. …”
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1259“…METHODS: The purpose of this review is to provide an update to previous summaries that determine the significance of animal models in studying the mechanisms of NEC. A large variety of animal models including rats, mice, rabbits, piglets, nonhuman primates, and quails have been described in literature. …”
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1260“…Aware of the growing attention being given to emerging RNA viruses, we reviewed the current knowledge on PBVs and described the current status of PBVs in animals.…”
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