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259761por Konda, Manikyeswara Rao, Alluri, Krishnaraju Venkata, Janardhanan, Prason Kumar, Trimurtulu, Golakoti, Sengupta, Krishanu“…METHODS: Four groups of Swiss albino mice (20–30 g body weight) (n = 6) were fed a standard laboratory diet and given Carboxymethylcellulose sodium (CMC), 150 mg/kg GMCT (GMCT-150), 300 mg/kg GMCT (GMCT-300) or 50 mg/kg Oxymetholone (OXY) via oral gavage for 21 days. On day 22, the animals’ physical performance and muscle strength were assessed in a forced swimming test (FST) and forelimb grip strength experiment, respectively. …”
Publicado 2018
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259762por Vora, Kalpit, Chen, Zhifeng, Su, Hua-Poo, Tang, Aimin, Cox, Kara, Callahan, Cheryl, Zhang, Lan, Patel, Sangita, Nahas, Debbie, Citron, Mike, Cejas, Pedro, Swoyer, Ryan, Luo, Bin, Eddins, Michael, Reid, John, Fridman, Arthur, Galli, Jennifer, Cosmi, Scott, Dhanasekeran, Govindarajan, Wen, Zhiyun, He, Xi, Wang, Dai, Heidecker, Gwen, Flynn, Jessica, Cook, James, Soisson, Stephen, Casimiro, Danilo, Bett, Andrew, Blair, Wade, Distefano, Daniel, Haines, Christopher“…In vivo cotton rat studies demonstrated protection of both the upper and lower respiratory tract of antibody-infused animals challenged with either RSV A or RSV B. CONCLUSION: Overall, the fully human mAb we have isolated has great potential to be developed for passive immune-prophylaxis in infants. …”
Publicado 2018
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259763por Zheng, Jim, Yant, Stephen R, Ahmadyar, Shekeba, Chan, Tiffany Y, Chiu, Anna, Cihlar, Tomas, Link, John O, Lu, Bing, Mwangi, Judy, Rowe, William, Schroeder, Scott D, Stepan, George J, Wang, Kelly Wei, Subramanian, Raju, Tse, Winston C“…CONCLUSION: GS-CA2 is a selective and first-in-class HIV capsid inhibitor with picomolar potency and potential to be clinically effective against a broad range of HIV-1 strains. In animals following a single SC injection, GS-CA2 maintained therapeutically relevant concentrations for >3 months. …”
Publicado 2018
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259764por Allwood, J. William, Xu, Yun, Martinez-Martin, Pilar, Palau, Raphaёlle, Cowan, Alexander, Goodacre, Royston, Marshall, Athole, Stewart, Derek, Howarth, Catherine“…INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of diseases. …”
Publicado 2019
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259765por Borghi, Sergio M., Fattori, Victor, Pinho-Ribeiro, Felipe A., Domiciano, Talita P., Miranda-Sapla, Milena M., Zaninelli, Tiago H., Casagrande, Rubia, Pinge-Filho, Phileno, Pavanelli, Wander R., Alves-Filho, Jose C., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.“…CX(3)CL1 mRNA expression was also detected in the ipsilateral DRG of infected mice at the 30th day post-infection, and the i.t. injection of TNF-α or IL-1β in naïve animals induced CX(3)CL1 mRNA expression in the spinal cord and ipsilateral DRG. …”
Publicado 2019
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259766por Li, Zhongxun, Yan, Guijun, Diao, Qiang, Yu, Fei, Li, Xin’an, Sheng, Xiaoqiang, Liu, Yong, Dai, Yimin, Zhou, Huaijun, Zhen, Xin, Hu, Yali, Péault, Bruno, Ding, Lijun, Sun, Haixiang, Li, Hairong“…To establish a rat model of uterine injury, a subset of uterine wall was then resected from each uterine horn in experimental animals. Female rats were randomly assigned to five groups, including a sham-operated group and four repair groups that received either PBS loaded on a collagen scaffold (collagen/PBS), En-PSCs loaded on a collagen scaffold (collagen/En-PSCs), En-PSCs with low CYR61 expression loaded on a collagen scaffold (collagen/si-CYR61 En-PSCs), and En-PSCs overexpressing CYR61 loaded on a collagen scaffold (collagen/ov-CYR61 En-PSCs). …”
Publicado 2019
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259767por H. Al Wattar, Bassel, Dodds, Julie, Placzek, Anna, Beresford, Lee, Spyreli, Eleni, Moore, Amanda, Gonzalez Carreras, Francisco J., Austin, Frances, Murugesu, Nilaani, Roseboom, Tessa J., Bes-Rastrollo, Maira, Hitman, Graham A., Hooper, Richard, Khan, Khalid S., Thangaratinam, Shakila“…We randomised inner-city pregnant women with metabolic risk factors (obesity, chronic hypertension, or hypertriglyceridaemia) to a Mediterranean-style diet with high intake of nuts, extra virgin olive oil, fruits, vegetables, nonrefined grains, and legumes; moderate to high consumption of fish; low to moderate intake of poultry and dairy products; low intake of red and processed meat; and avoidance of sugary drinks, fast food, and food rich in animal fat versus usual care. Participants received individualised dietary advice at 18, 20, and 28 weeks’ gestation. …”
Publicado 2019
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259768por Luo, Bin, Chen, Daiwen, Tian, Gang, Zheng, Ping, Yu, Jie, He, Jun, Mao, Xiangbin, Luo, Yuheng, Luo, Junqiu, Huang, Zhiqing, Yu, BingEnlace del recurso
Publicado 2019
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259769por Humam, Ali Merzza, Loh, Teck Chwen, Foo, Hooi Ling, Samsudin, Anjas Asmara, Mustapha, Noordin Mohamed, Zulkifli, Idrus, Izuddin, Wan IbrahimEnlace del recurso
Publicado 2019
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259770por Jiang, Wei-Wei, Wang, Yi-Meng, Wang, Xiao-Yu, Zhang, Qian, Zhu, Si-Man, Zhang, Chun-Lei“…Then HaCaT cells were assigned to normal saline (NS) control group, matrine (0.4 mg/mL) group, acitretin (10 μmol/L) group, and matrine plus acitretin group, and the above methods were repeated. In animal experiments, the cumulative score (erythema, scaling, thickening) as a measure of the severity of inflammation was used to measure the skin performance of mice after treated with matrine 50 mg/kg, acitretin 4.5 mg/kg or combination of the two drugs on the psoriasis-like mouse models, respectively. …”
Publicado 2019
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259771por Zhu, Xiao-Long, Zhang, Tao, Xu, Zhen-Qiang, Ma, Xiao-Chun, Wang, Zheng-Jun, Zou, Cheng-Wei, Li, Jing-Xin, Jing, Hai-Yan“…METHODS: The Dahl salt-sensitive (DS) and salt-resistant (DR) rats were used in this study. Animals were matched according to their age and weight, and then placed on either a high-salt (HS, 8%) or a normal-salt (NS, 0.4%) diet for 6 weeks randomly using random number table. …”
Publicado 2020
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259772por Romero-Bautista, Yessica Angélica, Moreno-Calles, Ana Isabel, Alvarado-Ramos, Fernando, Reyes Castillo, Maurino, Casas, Alejandro“…The following aspects were addressed with local people: (i) the bird species of Zapotitlán recognized by them; (ii) the biological, ecological, and behavioral knowledge about these species; (iii) the description of practices of use and management of these animals; (iv) the perceived changes regarding presence and abundance of the wild birds recognized; and (v) the regulations of these practices and uses. …”
Publicado 2020
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259773por Léger, Elsa, Borlase, Anna, Fall, Cheikh B, Diouf, Nicolas D, Diop, Samba D, Yasenev, Lucy, Catalano, Stefano, Thiam, Cheikh T, Ndiaye, Alassane, Emery, Aidan, Morrell, Alice, Rabone, Muriel, Ndao, Momar, Faye, Babacar, Rollinson, David, Rudge, James W, Sène, Mariama, Webster, Joanne P“…Additionally, five malacological surveys of snail intermediate hosts were carried out at each site in open water sources used by the communities and their animals. FINDINGS: In May to August, 2016, we surveyed 375 children and 20 adults from Richard Toll and Lac de Guiers, and 201 children and 107 adults from Barkedji and Linguère; in October, 2017, to January, 2018, we surveyed 386 children and 88 adults from Richard Toll and Lac de Guiers, and 323 children and 85 adults from Barkedji and Linguère. …”
Publicado 2020
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259774por Pérez-Manrique, Lucia, León-Pérez, Karina, Zamora-Sánchez, Emmanuel, Davies, Sarah, Ober, Christopher, Wilson, Bethany, McGreevy, PaulEnlace del recurso
Publicado 2020
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259775por Briaux, Justine, Martin-Prevel, Yves, Carles, Sophie, Fortin, Sonia, Kameli, Yves, Adubra, Laura, Renk, Andréa, Agboka, Yawavi, Romedenne, Magali, Mukantambara, Félicité, Van Dyck, John, Boko, Joachim, Becquet, Renaud, Savy, Mathilde“…UCTs positively impacted both mothers’ and children’s (18–23 months) consumption of animal source foods (ASFs) (respectively, DD = +4.5 pp, ROR: 2.24, 95% CI: 1.09–4.61, p = 0.029 and DD = +9.1 pp, ROR: 2.65, 95% CI: 1.01–6.98, p = 0.048) and household food insecurity (DD = −10.7 pp, ROR: 0.63, 95% CI: 0.43–0.91, p = 0.016). …”
Publicado 2020
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259776por Krauze, Magdalena, Cendrowska-Pinkosz, Monika, Matuseviĉius, Paulius, Stępniowska, Anna, Jurczak, Paweł, Ognik, KatarzynaEnlace del recurso
Publicado 2021
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259777por Abd Elfatah, Khaled Saad, Elabasy, Moshira Abas, El-khyate, Faris, Elmahallawy, Ehab Kotb, Mosad, Samah M., El-Gohary, Fatma A., Abdo, Walied, Al-Brakati, Ashraf, Seadawy, Mohamed G., Tahoon, Abd Elnaby, El-Gohary, Abd ElgalilEnlace del recurso
Publicado 2021
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259778por Mangi, Mazhar Hussain, Hussain, Tariq, Shahid, Muhammad Suhaib, Sabir, Naveed, Kalhoro, Muhammad Saleem, Zhou, Xiangmei, Yuan, JianminEnlace del recurso
Publicado 2021
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259779por Ariyarathne, Hewa Bahithige Pavithra Chathurangi, Correa-Luna, Martin, Blair, Hugh, Garrick, Dorian, Lopez-Villalobos, NicolasEnlace del recurso
Publicado 2021
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259780“…BACKGROUND: Type 1 diabetes (T1DM) is associated with premature cardiovascular disease (CVD) and a pro-inflammatory state whilst the proangiogenic miR-126-3p/-5p may play a role in CVD. Animal studies established miR-126 to be pro-angiogenic. …”
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