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681por Kugler, Franziska, Drexler, Ingo, Protzer, Ulrike, Hoffmann, Dieter, Moeini, Hassan“…BACKGROUND: Recombinant Modified Vaccinia Virus Ankara has been employed as a safe and potent viral vector vaccine against infectious diseases and cancer. …”
Publicado 2019
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682por McMahon, Meagan, Asthagiri Arunkumar, Guha, Liu, Wen-Chun, Stadlbauer, Daniel, Albrecht, Randy A., Pavot, Vincent, Aramouni, Mario, Lambe, Teresa, Gilbert, Sarah C., Krammer, Florian“…Furthermore, replication deficient viral vectors based on Chimpanzee Adenovirus Oxford 1 (ChAdOx1) and modified vaccinia Ankara (MVA) virus expressing the influenza virus internal antigens, the nucleoprotein (NP) and matrix 1 (M1) protein, can induce strong heterosubtypic influenza virus-specific T cell responses in vaccinated individuals. …”
Publicado 2019
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683por Asthagiri Arunkumar, Guha, McMahon, Meagan, Pavot, Vincent, Aramouni, Mario, Ioannou, Andriani, Lambe, Teresa, Gilbert, Sarah, Krammer, Florian“…For this purpose, replication deficient recombinant viral vectors based on Chimpanzee Adenovirus Oxford 1 and Modified Vaccinia Ankara virus are used to express the viral nucleoprotein and the matrix protein 1. …”
Publicado 2019
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684“…METHODS: This interventional study was conducted on women who were between the ages of 30 and 65 years in three Turkish provinces (Ankara, Malatya, and Trabzon). Five hundred twenty home visits were made, and 356 women who did not have a Pap smear test within the previous year were invited for cervical cancer screening. …”
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685por Margolin, Emmanuel, Chapman, Rosamund, Meyers, Ann E., van Diepen, Michiel T., Ximba, Phindile, Hermanus, Tandile, Crowther, Carol, Weber, Brandon, Morris, Lynn, Williamson, Anna-Lise, Rybicki, Edward P.“…Furthermore, a heterologous prime-boost regimen employing a recombinant modified vaccinia Ankara (rMVA) vaccine, followed by boosts with the SEC-purified protein, significantly improved the immunogenicity. …”
Publicado 2019
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686por Medina-Echeverz, José, Hinterberger, Maria, Testori, Marco, Geiger, Marlene, Giessel, Raphael, Bathke, Barbara, Kassub, Ronny, Gräbnitz, Fabienne, Fiore, Giovanna, Wennier, Sonia T., Chaplin, Paul, Suter, Mark, Hochrein, Hubertus, Lauterbach, Henning“…Here we report the use of recombinant modified vaccinia virus Ankara (rMVA) encoding costimulatory CD40L against solid tumors. …”
Publicado 2019
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687“…We have generated recombinant modified vaccinia virus Ankara (recMVA) vaccines via MVA-BAC homologous recombination technology expressing MHV-68 ORF6 and ORF61 antigens encoding both MHC class I and II-restricted epitopes. …”
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688“…METHODS: A total of 257 patients that underwent CRC and HIPEC between 2015 and 2017 in the Department of Surgical Oncology, Faculty of Medicine, Ankara University, were retrospectively analyzed. …”
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689por Pérez, Patricia, Marín, María Q., Lázaro-Frías, Adrián, Sorzano, Carlos Óscar S., Di Pilato, Mauro, Gómez, Carmen E., Esteban, Mariano, García-Arriaza, Juan“…Highly attenuated poxviral vectors, such as modified vaccinia virus ankara (MVA), are promising vaccine candidates against several infectious diseases. …”
Publicado 2019
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690por Contreras, Heidi, Wussow, Felix, Fernández-Alarcón, Claudia, Bierle, Craig, Nguyen, Jenny, Diamond, Don J., Schleiss, Mark R.“…We compared CMV gB (gpgB), gH/gL (gp75/gL), and pentameric complex (gpPC, composed of gH/gL/GP129/GP131/GP133) vaccines in a guinea pig CMV (GPCMV) congenital infection model. (2) Methods: Modified vaccinia virus Ankara (MVA) vaccines expressing GPCMV glycoproteins were used to immunize GPCMV-seronegative, female Hartley guinea pigs (three-dose series, 3 × 10(7) pfu/dose). …”
Publicado 2019
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691por Kalodimou, Georgia, Veit, Svenja, Jany, Sylvia, Kalinke, Ulrich, Broder, Christopher C., Sutter, Gerd, Volz, Asisa“…Modified Vaccinia virus Ankara (MVA), a safety-tested strain of vaccinia virus for preclinical and clinical vaccine research, was used for the generation of MVA–NiV-G candidate vaccines expressing different versions of recombinant NiV-G. …”
Publicado 2019
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692por Prkno, Almut, Hoffmann, Donata, Kaiser, Matthias, Goerigk, Daniela, Pfeffer, Martin, Winter, Karsten, Vahlenkamp, Thomas W., Beer, Martin, Starke, Alexander“…In the present study, modified vaccinia virus Ankara (MVA) vaccine, which has been successfully used in many animal species, was used in a prime-boost vaccination regimen in two alpaca herds with a history of CPXV infection. …”
Publicado 2020
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693por Rollier, C S, Verschoor, E J, Verstrepen, B E, Drexhage, J A R, Paranhos-Baccala, G, Liljeström, P, Sutter, G, Arribillaga, L, Lasarte, J J, Bartosch, B, Cosset, F-L, Inchauspe, G, Heeney, J L“…Four vectors, DNA, SFV, human serotype 5 adenovirus (HuAd5) and Modified Vaccinia Ankara (MVA) poxvirus, all expressing hepatitis C virus Core, E1, E2 and NS3, were combined in three prime-boost regimen, and their ability to elicit immune responses against HCV antigens in rhesus macaques was explored and compared. …”
Publicado 2016
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694por Leemans, Ingrid, Brown, Duncan, Hooshmand-Rad, Parviz, Kirvar, Erol, Uggla, Arvid“…In a series of experiments, sporozoite stabilates of a Theileria lestoquardi (Lahr) and a T. annulata (Ankara) stock prepared from Hyalomma anatolicum anatolicum ticks, were used to examine the infectivity of both parasite species for sheep and cattle and to study the development of cross-immunity between these parasite species. …”
Publicado 1999
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695por Chapman, Rosamund, van Diepen, Michiel, Galant, Shireen, Kruse, Elizabeth, Margolin, Emmanuel, Ximba, Phindile, Hermanus, Tandile, Moore, Penny, Douglass, Nicola, Williamson, Anna-Lise, Rybicki, Edward“…Recombinant DNA and modified vaccinia Ankara (MVA) vaccines expressing HIV-1 subtype C mosaic Gag and gp150 Env or either of the chimeras were generated. …”
Publicado 2020
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696por Barnowski, Cornelia, Ciupka, Gregor, Tao, Ronny, Jin, Lei, Busch, Dirk H., Tao, Sha, Drexler, Ingo“…Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus and currently under investigation as a promising vaccine vector against infectious diseases and cancer. …”
Publicado 2020
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697por Palli, Rohith, Seaton, Kelly E., Piepenbrink, Michael S., Hural, John, Goepfert, Paul A., Laher, Fatima, Buchbinder, Susan P., Churchyard, Gavin, Gray, Glenda E., Robinson, Harriet L., Huang, Yunda, Janes, Holly, Kobie, James J., Keefer, Michael C., Tomaras, Georgia D., Thakar, Juilee“…Compared to protein-boosted regimens, half-lives of gp120-specific antibodies were longer but peak magnitudes were lower in Modified Vaccinia Ankara (MVA)-boosted regimens. Furthermore, gp120-specific B cell transcriptomics from MVA-boosted and protein-boosted vaccines revealed a distinct signature at a peak (2 weeks after last vaccination) including CD19, CD40, and FCRL2-5 activation along with increased B cell receptor signaling. …”
Publicado 2020
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698por Yapar, Aliekber, Ulucaköy, Coşkun, Sezgin, Erdem Aras, Atalay, İsmail Burak, Ekşioğlu, Mehmet Fatih“…PATIENTS AND METHODS: One-hundred-and-one patients (44 males, 57 females; mean age 53.6±11.5 years; range, 21 to 85 years) diagnosed with enchondroma and low-grade chondrosarcoma in Ankara Oncology Training and Research Hospital between January 2010 and December 2019 were included in this retrospective study. …”
Publicado 2020
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699por Morelli, María Paula, Del Medico Zajac, María Paula, Pellegrini, Joaquín Miguel, Amiano, Nicolás Oscar, Tateosian, Nancy Liliana, Calamante, Gabriela, Gherardi, María Magdalena, García, Verónica Edith“…The Modified Vaccinia Ankara (MVA) vaccine vector expressing the mycobacterial antigen 85A (MVA85A) was demonstrated to be safe, although it did not improve BCG efficacy, denoting the need to search for improved tuberculosis vaccines. …”
Publicado 2020
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700por Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Alonso-Ravelo, Ruymán, Calvo-Pinilla, Eva, Marín-López, Alejandro, Moreno, Sandra, Lorenzo, Gema, Benavides, Julio, Gilbert, Sarah, Nogales, Aitor, Ortego, Javier“…In this work, we have engineered multiserotype BTV vaccine candidates based on recombinant chimpanzee adenovirus (ChAdOx1) and modified vaccinia virus Ankara (MVA) vectors expressing the NS1 protein of BTV-4 or its truncated form NS1-Nt. …”
Publicado 2020
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