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781por Dhama, Kuldeep, Karthik, Kumaragurubaran, Khandia, Rekha, Chakraborty, Sandip, Munjal, Ashok, Latheef, Shyma K., Kumar, Deepak, Ramakrishnan, Muthannan Andavar, Malik, Yashpal Singh, Singh, Rajendra, Malik, Satya Veer Singh, Singh, Raj Kumar, Chaicumpa, Wanpen“…These include recombinant viral vector (recombinant vesicular stomatitis virus vector, chimpanzee adenovirus type 3-vector, and modified vaccinia Ankara virus), Ebola virus-like particles, virus-like replicon particles, DNA, and plant-based vaccines. …”
Publicado 2018
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782por Aksular, Mine, Calvo-Pinilla, Eva, Marín-López, Alejandro, Ortego, Javier, Chambers, Adam C., King, Linda A., Castillo-Olivares, Javier“…Various studies showed that baculovirus-expressed AHSV-VP2 or modified Vaccinia Ankara virus expressing AHSV-VP2 (MVA-VP2) induced virus neutralising antibodies and protective immunity in small animals and horses. …”
Publicado 2018
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783por Tiono, Alfred B., Nébié, Issa, Anagnostou, Nicholas, Coulibaly, Aboubacar S., Bowyer, Georgina, Lam, Erika, Bougouma, Edith C., Ouedraogo, Alphonse, Yaro, Jean Baptist B., Barry, Aïssata, Roberts, Rachel, Rampling, Tommy, Bliss, Carly, Hodgson, Susanne, Lawrie, Alison, Ouedraogo, Amidou, Imoukhuede, Egeruan Babatunde, Ewer, Katie J., Viebig, Nicola K., Diarra, Amidou, Leroy, Odile, Bejon, Philip, Hill, Adrian V. S., Sirima, Sodiomon B.“…BACKGROUND: Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified Vaccinia Virus Ankara (MVA) vectored vaccines is a strategy previously shown to provide substantial protective efficacy against P. falciparum infection in United Kingdom adult Phase IIa sporozoite challenge studies (approximately 20–25% sterile protection with similar numbers showing clear delay in time to patency), and greater point efficacy in a trial in Kenyan adults. …”
Publicado 2018
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784por Munusamy Ponnan, Sivasankaran, Pattabiram, Sathyamurthy, Thiruvengadam, Kannan, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Bergin, Philip, T. Kopycinski, Jakub, Gilmour, Jill, Kumar, Sriram, Muthu, Malathy, Subramaniam, Sudha, Swaminathan, Soumya, Prasad Tripathy, Srikanth, Luke, Hanna Elizabeth“…A Phase I HIV-1 prophylactic vaccine trial sponsored by the International AIDS Vaccine Initiative (IAVI) was conducted in India in 2009.The trial tested a HIV-1 subtype C vaccine in a prime-boost regimen, comprising of a DNA prime (ADVAX) and Modified Vaccine Ankara (MVA) (TBC-M4) boost. The trial reported that the vaccine regimen was safe, well tolerated, and resulted in enhancement of HIV-specific immune responses. …”
Publicado 2019
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785por Khanna, Mayank, Jackson, Ronald J., Alcantara, Sheilajen, Amarasena, Thakshila H., Li, Zheyi, Kelleher, Anthony D., Kent, Stephen J., Ranasinghe, Charani“…We evaluated an intranasal recombinant Fowlpox virus (rFPV) priming vaccine followed by intramuscular Modified Vaccinia Ankara (rMVA) booster vaccine, both expressing SIV antigens. …”
Publicado 2019
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786por Venkatraman, Navin, Ndiaye, Birahim Pierre, Bowyer, Georgina, Wade, Djibril, Sridhar, Saranya, Wright, Daniel, Powlson, Jonathan, Ndiaye, Ibrahima, Dièye, Siry, Thompson, Craig, Bakhoum, Momar, Morter, Richard, Capone, Stefania, Del Sorbo, Mariarosaria, Jamieson, Sophie, Rampling, Tommy, Datoo, Mehreen, Roberts, Rachel, Poulton, Ian, Griffiths, Oliver, Ballou, W Ripley, Roman, François, Lewis, David J M, Lawrie, Alison, Imoukhuede, Egeruan, Gilbert, Sarah C, Dieye, Tandakha N, Ewer, Katie J, Mboup, Souleymane, Hill, Adrian V S“…METHODS: We undertook 2 phase 1 studies assessing safety and immunogenicity of the viral vector modified vaccinia Ankara virus vectored Ebola Zaire vaccine (MVA-EBO-Z), manufactured rapidly on a new duck cell line either alone or in a heterologous prime-boost regimen with recombinant chimpanzee adenovirus type 3 vectored Ebola Zaire vaccine (ChAd3-EBO-Z) followed by MVA-EBO-Z. …”
Publicado 2019
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787por Hancock, Gemma, Blight, Joshua, Lopez-Camacho, Cesar, Kopycinski, Jakub, Pocock, Mamatha, Byrne, Wendy, Price, Michael J., Kemlo, Phillip, Evans, Ranoromanana Ionitiana, Bloss, Angela, Saunders, Kathryn, Kirton, Richard, Andersson, Monique, Hellner, Karin, Reyes-Sandoval, Arturo, Dorrell, Lucy“…We designed the synthetic gene ‘5GHPV3′ by selecting conserved regions from each of the six early proteins and generating consensus sequences to represent five hrHPV genotypes. 5GHPV3 was delivered by plasmid DNA, chimpanzee adenovirus (ChAdOx1) and modified vaccinia Ankara (MVA) vectors in prime-boost regimens to mice. …”
Publicado 2019
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788por Tezer, Hasan, Sucaklı, Iclal Ayrancı, Saylı, Tulin Revide, Celikel, Elif, Yakut, Ibrahim, Kara, Ateş, Tunc, Bahattin, Ergonul, Onder“…STUDY DESIGN: The children infected with CCHF virus between April 2008 and October 2009, and hospitalised in Ankara Dışkapı Children's and Research Hospital were included. …”
Publicado 2010
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789por Pereira, Anna C.T.C., Soares-Martins, Jamária A.P., Leite, Flávia G.G., Da Cruz, André F.P., Torres, Alice A., Souto-Padrón, Thais, Kroon, Erna G., Ferreira, Paulo C.P., Bonjardim, Cláudio A.“…In this study, we evaluated whether pretreatment with SP600125 was able to prevent Orthopoxviruses Vaccinia virus (VACV), Cowpox virus (CPXV) and modified Vaccinia virus Ankara (MVA) replication. We found that incubation with SP600125 not only blocked virus-stimulated JNK phosphorylation, but also, significantly reduced virus production. …”
Publicado 2012
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790por Pérez, Patricia, Marín, María Q., Lázaro-Frías, Adrián, Sorzano, Carlos Óscar S., Gómez, Carmen E., Esteban, Mariano, García-Arriaza, Juan“…We previously described an HIV/AIDS vaccine based on the modified vaccinia virus Ankara (MVA) expressing HIV-1 gp120 and Gag-Pol-Nef (GPN) of clade B (termed MVA-B), which showed moderate immunogenicity in phase I prophylactic and therapeutic clinical trials. …”
Publicado 2020
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791“…SETTING: Yale School of Medicine (New Haven, USA) and Gazi University School of Medicine (Ankara, Turkey). PATIENTS OR OTHER PARTICIPANTS: A total of 141 women undergoing infertility evaluation and treatment. …”
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792por Wagstaffe, Helen R., Clutterbuck, Elizabeth A., Bockstal, Viki, Stoop, Jeroen N., Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D., Pollard, Andrew J., Riley, Eleanor M., Goodier, Martin R.“…METHODS: The novel 2-dose heterologous Adenovirus type 26.ZEBOV (Ad26.ZEBOV) and modified vaccinia Ankara-BN-Filo (MVA-BN-Filo) vaccine regimen is safe and provides specific immunity against Ebola glycoprotein, and is currently in phase 2 and 3 studies. …”
Publicado 2020
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793por Calvo-Pinilla, Eva, Marín-López, Alejandro, Moreno, Sandra, Lorenzo, Gema, Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Benavides, Julio, Nogales, Aitor, Blasco, Rafael, Brun, Alejandro, Ortego, Javier“…In this work, we report a dual vaccine that simultaneously induces protective immune responses against BTV and RVFV based on modified vaccinia Ankara virus (MVA) expressing BTV proteins VP2, NS1, or a truncated form of NS1 (NS1-Nt), and RVFV Gn and Gc glycoproteins. …”
Publicado 2020
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794por Om, Kier, Paquin-Proulx, Dominic, Montero, Maria, Peachman, Kristina, Shen, Xiaoying, Wieczorek, Lindsay, Beck, Zoltan, Weiner, Joshua A., Kim, Dohoon, Li, Yifan, Mdluli, Thembi, Shubin, Zhanna, Bryant, Christopher, Sharma, Vishakha, Tokarev, Andrey, Dawson, Peter, White, Yohann, Appelbe, Oliver, Klatt, Nichole R., Tovanabutra, Sodsai, Estes, Jacob D., Matyas, Gary R., Ferrari, Guido, Alving, Carl R., Tomaras, Georgia D., Ackerman, Margaret E., Michael, Nelson L., Robb, Merlin L., Polonis, Victoria, Rolland, Morgane, Eller, Michael A., Rao, Mangala, Bolton, Diane L.“…To augment HIV-1 pox-protein vaccine immunogenicity using a next generation adjuvant, a prime-boost strategy of recombinant modified vaccinia virus Ankara and multimeric Env gp145 was evaluated in macaques with either aluminum (alum) or a novel liposomal monophosphoryl lipid A (MPLA) formulation adsorbed to alum, ALFA. …”
Publicado 2020
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795por Hartnell, Felicity, Esposito, Ilaria, Swadling, Leo, Brown, Anthony, Phetsouphanh, Chansavath, de Lara, Catherine, Gentile, Chiara, Turner, Bethany, Dorrell, Lucy, Capone, Stefania, Folgori, Antonella, Barnes, Eleanor, Klenerman, Paul“…APPROACH AND RESULTS: We analyzed HCV‐specific CD4(+) T‐cell populations using major histocompatibility complex class II tetramers in volunteers undergoing HCV vaccination with recombinant HCV adenoviral/modified vaccinia Ankara viral vectors. Peptide‐specific T‐cell responses were tracked over time, and functional (proliferation and cytokine secretion) and phenotypic (cell surface and intranuclear) markers were assessed using flow cytometry. …”
Publicado 2020
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796“…MATERIALS AND METHODS: A total of 79 patients with 30 being female (38%) and 49 male (62%) who were diagnosed with gastric signet ring cell adenocarcinoma in the Medical Oncology Department of Ankara Numune Training and Research Hospital between January 2004 and October 2015 were retrospectively evaluated. …”
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797por Wagstaffe, Helen R., Susannini, Giada, Thiébaut, Rodolphe, Richert, Laura, Lévy, Yves, Bockstal, Viki, Stoop, Jeroen N., Luhn, Kerstin, Douoguih, Macaya, Riley, Eleanor M., Lacabaratz, Christine, Goodier, Martin R.“…The two-dose heterologous Ebola virus vaccine regimen, adenovirus type 26.ZEBOV followed by modified vaccinia Ankara-BN-Filo (EBOVAC2 consortium, EU Innovative Medicines Initiative), induces NK cell activation and anti-Ebola glycoprotein (GP) antibody-dependent NK cell activation post-dose 1, which is further elevated post-dose 2. …”
Publicado 2021
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798por Sarzhanov, Fakhriddin, Dogruman-Al, Funda, Santin, Monica, Maloney, Jenny G., Gureser, Ayse Semra, Karasartova, Djursun, Taylan-Ozkan, Aysegul“…MATERIAL AND METHODS: Individual stool specimens were collected from 245 immunodeficient and 193 immunocompetent diarrheic patients between March 2017 and December 2019 at the Gazi University Training and Research Hospital in Ankara, Turkey. Samples were screened for Blastocystis sp. and D. fragilis by conventional and molecular methods. …”
Publicado 2021
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799por Zaric, Marija, Marini, Arianna, Nielsen, Carolyn M., Gupta, Gaurav, Mekhaiel, David, Pham, Thao P., Elias, Sean C., Taylor, Iona J., de Graaf, Hans, Payne, Ruth O., Li, Yuanyuan, Silk, Sarah E., Williams, Chris, Hill, Adrian V. S., Long, Carole A., Miura, Kazutoyo, Biswas, Sumi“…We examined Pfs25-specific B cell and T follicular helper (Tfh) cell responses in mice and humans after vaccination with Pfs25-IMX313 encoded by replication-deficient chimpanzee adenovirus serotype 63 (ChAd63) and the attenuated orthopoxvirus modified vaccinia virus Ankara (MVA) delivered in the heterologous prime-boost regimen via intramuscular route. …”
Publicado 2021
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800por KURTİPEK, Fatma Burçin, KAVURT, Ahmet Vedat, ÇELİKEL, Elif, UYAR, Emel, AZAK, Emine, PERK, Oktay, Yaralı, Neşe, Özbek, Namık Yaşar“…METHODOLOGY: In this study, we aimed to investigate the effect of ABO blood groups, hematological parameters (white blood cell, absolute neutrophil, absolute lymphocyte, platelet count, prothrombin time, activated partial thromboplastin time), cardiac parameters (troponin, brain natriuretic factor, electrocardiography) of patients diagnosed with MIS-C in Ankara City Hospital during the pandemic shortening fraction, ejection fraction), infectious parameters (c-reactive protein, interleukin-6, sedimentation) were analyzed retrospectively. …”
Publicado 2021
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