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801por Graalmann, Theresa, Borst, Katharina, Manchanda, Himanshu, Vaas, Lea, Bruhn, Matthias, Graalmann, Lukas, Koster, Mario, Verboom, Murielle, Hallensleben, Michael, Guzmán, Carlos Alberto, Sutter, Gerd, Schmidt, Reinhold E, Witte, Torsten, Kalinke, Ulrich“…Moreover, B cell-deficient JHT mice infected with mouse-adapted Influenza or modified vaccinia virus Ankara showed less vigorous expansion of virus-specific CD8(+) T cells than wild type mice. …”
Publicado 2021
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802por Chiuppesi, Flavia, Nguyen, Vu H., Park, Yoonsuh, Contreras, Heidi, Karpinski, Veronica, Faircloth, Katelyn, Nguyen, Jenny, Kha, Mindy, Johnson, Daisy, Martinez, Joy, Iniguez, Angelina, Zhou, Qiao, Kaltcheva, Teodora, Frankel, Paul, Kar, Swagata, Sharma, Ankur, Andersen, Hanne, Lewis, Mark G., Shostak, Yuriy, Wussow, Felix, Diamond, Don J.“…We developed COH04S1, a synthetic multiantigen modified vaccinia Ankara-based SARS-CoV-2 vaccine that co-expresses spike and nucleocapsid antigens. …”
Publicado 2022
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803por Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Calvo-Pinilla, Eva, Marín-López, Alejandro, Lorenzo, Gema, Sánchez-Cordón, Pedro, Moreno, Sandra, Benavides, Julio, Gilbert, Sarah, Nogales, Aitor, Ortego, Javier“…In this work, we report modified vaccinia virus Ankara (MVA) and ChAdOx1-vectored vaccines designed to simultaneously express the immunogenic NS1 protein and/or NS2-Nt, the N-terminal half of protein NS2 (NS2(1-180)). …”
Publicado 2022
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804por Pérez, Patricia, Lázaro-Frías, Adrián, Zamora, Carmen, Sánchez-Cordón, Pedro J., Astorgano, David, Luczkowiak, Joanna, Delgado, Rafael, Casasnovas, José M., Esteban, Mariano, García-Arriaza, Juan“…We generated an optimized COVID-19 vaccine candidate based on the modified vaccinia virus Ankara (MVA) vector expressing a full-length prefusion-stabilized SARS-CoV-2 spike (S) protein, termed MVA-CoV2-S(3P). …”
Publicado 2022
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805por Sahin, Dilek, Tanacan, Atakan, Anuk, Ali Taner, Sinaci, Selcan, Besimoglu, Berhan, Oluklu, Deniz, Hendem, Derya Uyan, Beser, Dilek Menekse, Yildirim, Muradiye, Sakcak, Bedri, Erol, Seyit Ahmet, Colakoglu, Yeliz, Ayhan, Sule Goncu, Turgut, Ezgi, Unlu, Serpil, Canpolat, Fuat Emre, Izdes, Seval, Turan, Sema, Surel, Aziz Ahmet, Tekin, Ozlem Moraloglu“…METHODS: This prospective cohort study includes pregnant women with SARS-CoV-2 who were followed-up at Ankara City Hospital between 11, March 2020 and 15, September 2021. …”
Publicado 2022
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806por Vijayan, K. K. Vidya, Cross, Kaitlyn A., Curtis, Alan D., Van Rompay, Koen K. A., Pollara, Justin, Fox, Christopher B., Tomai, Mark, Hanke, Tomáš, Fouda, Genevieve, Hudgens, Michael G., Permar, Sallie R., De Paris, Kristina“…The current study compared the whole blood molecular immune signatures of a 3M-052-SE adjuvanted HIV Env protein vaccine to a regimen combining the adjuvanted Env protein with simultaneous administration of a modified Vaccinia Ankara vector expressing HIV Env in infant rhesus macaques at days 0, 1, and 3 post vaccine prime. …”
Publicado 2022
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807por Ventura, John D., Nkolola, Joseph P., Chandrashekar, Abishek, Borducchi, Erica N., Liu, Jinyan, Mercado, Noe B., Hope, David L., Giffin, Victoria M., McMahan, Katherine, Geleziunas, Romas, Murry, Jeffrey P., Yang, Yunling, Lewis, Mark G., Pau, Maria G., Wegmann, Frank, Schuitemaker, Hanneke, Fray, Emily J., Kumar, Mithra R., Siliciano, Janet D., Siliciano, Robert F., Robb, Merlin L., Michael, Nelson L., Barouch, Dan H.“…In this study, we investigated the therapeutic efficacy of a vaccine consisting of adenovirus serotype 26 (Ad26) and modified vaccinia Ankara (MVA) with or without an SIV Envelope (Env) gp140 protein with alum adjuvant in combination with the TLR7 agonist vesatolimod (GS-9620) in 36 ART-suppressed, SIVmac251-infected rhesus macaques. …”
Publicado 2022
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808por Crausaz, Morgane, Monneret, Guillaume, Conti, Filippo, Lukaszewicz, Anne-Claire, Marchand, Jean-Baptiste, Martin, Perrine, Inchauspé, Geneviève, Venet, Fabienne“…A novel virotherapy based on the non-propagative Modified Virus Ankara (MVA) expressing the human interleukin-7 (hIL-7) cytokine fused to an Fc fragment, MVA-hIL-7-Fc, was developed and shown to enhance innate and adaptive immunity and confer survival advantages in murine sepsis models. …”
Publicado 2022
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809por Çekmen, Nedim, Ersoy, Zeynep, Günay, Yağız ilteriş, Ghavam, Amir Aslan, Tufan, Muhammed Yavuz Selim, Şahin, İbrahim Mete“…MATERIALS AND METHODS: This retrospective cohort study included 352 hospitalized adult patients from Baskent University Hospital in Ankara who were confirmed cases of COVID-19 between March 2020 and March 2021. …”
Publicado 2022
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810por Kostik, Mikhail, Akca Kaya, Ummusen, Zhogova, Olga V., Sag, Erdal, Suspitsin, Evgeny N., Nizhnik, Viktoriya I., Tumakova, Anastasiya V., Ivanovskiy, Sergey V., Lagunova, Natalia V., Bilginer, Yelda, Ozen, Seza“…MATERIALS AND METHODS: All newly diagnosed familial Mediterranean fever patients with Crimean Tatar nationality (n = 18) in Children’s Regional Hospital in Simferopol were enrolled in the study and were compared to 40 familial Mediterranean fever cases followed up at Hacettepe University, Ankara, Turkey. The distribution of MEFV alleles was assessed in the 127 unrelated healthy Crimean Tatar adults aged 20 years or more from different parts of the Crimea peninsula. …”
Publicado 2022
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811por Vardeu, Antonella, Davis, Charlotte, McDonald, Ian, Stahlberg, Guilherme, Thapa, Barsha, Piotrowska, Kinga, Marshall, Margaret A, Evans, Thomas, Wheeler, Vicky, Sebastian, Sarah, Anderson, Katie“…METHODS: The coding sequences for four antigens expressed in prostate cancer, 5T4, PSA, PAP, and STEAP1, were inserted into replication-incompetent chimpanzee adenovirus Oxford 1 (ChAdOx1) and into replication-deficient modified vaccinia Ankara (MVA). In four strains of mice, ChAdOx1 prime was delivered intramuscularly, with an MVA boost delivered by either IM or intravenous routes. …”
Publicado 2022
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812por Mitjà, Oriol, Ogoina, Dimie, Titanji, Boghuma K, Galvan, Cristina, Muyembe, Jean-Jacques, Marks, Michael, Orkin, Chloe M“…The current strategy for post-exposure prophylaxis or pre-exposure prophylaxis for people at high risk is vaccination with the non-replicating modified vaccinia Ankara. Antiviral treatment and vaccines are not yet available in endemic countries in Africa.…”
Publicado 2023
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813por Coupet, Charles-Antoine, Dubois, Clarisse, Evlachev, Alexeï, Kehrer, Nadine, Baldazza, Marie, Hofman, Sam, Vierboom, Michel, Martin, Perrine, Inchauspe, Geneviève“…MVA-hIL-7-Fc is a non-replicative recombinant Modified Vaccinia virus Ankara encoding the human interleukin-7 fused to human IgG2 Fc fragment. …”
Publicado 2022
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814por Meyer zu Natrup, Christian, Tscherne, Alina, Dahlke, Christine, Ciurkiewicz, Malgorzata, Shin, Dai-Lun, Fathi, Anahita, Rohde, Cornelius, Kalodimou, Georgia, Halwe, Sandro, Limpinsel, Leonard, Schwarz, Jan H., Klug, Martha, Esen, Meral, Schneiderhan-Marra, Nicole, Dulovic, Alex, Kupke, Alexandra, Brosinski, Katrin, Clever, Sabrina, Schünemann, Lisa-Marie, Beythien, Georg, Armando, Federico, Mayer, Leonie, Weskamm, Marie L., Jany, Sylvia, Freudenstein, Astrid, Tuchel, Tamara, Baumgärtner, Wolfgang, Kremsner, Peter, Fendel, Rolf, Addo, Marylyn M., Becker, Stephan, Sutter, Gerd, Volz, Asisa“…A recombinant modified vaccinia virus Ankara (MVA) expressing native, full-length S protein (MVA-SARS-2-S) is currently under investigation as a candidate vaccine in phase I clinical studies. …”
Publicado 2022
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815“…This retrospective study was carried out at Lokman Hekim University, Ankara, Turkey between January 1, 2021 and January 1, 2022. …”
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816por Elati, Khawla, Zweygarth, Erich, Mhadhbi, Moez, Darghouth, Mohamed Aziz, Nijhof, Ard M.“…In the second experiment, a Tunisian cell line (Hessiene) cryopreserved in ISF-1 with 5%[v/v] dimethylsulfoxide (DMSO) grewbetter after thawing in RPMI-FBS compared to ISF-1 with a highly significant difference in cell growth (p < 0.001), whereas the third experiment showed that the Ankara cell line had similar growth characteristics in both RPMI-FBS and ISF-1 before and after thawing, with a shorter generation doubling time in ISF-1 than in RPMI-FBS (p = 0.23). …”
Publicado 2022
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817“…MATERIALS AND METHODS: A survey of awareness of color blindness among 710 students (males: n=271; females: n=439) in the faculty of dentistry and dental prosthesis technology program of Gazi University and Ankara Medipol University in 2019–2021 was conducted. …”
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818por Nyombayire, Julien, Ingabire, Rosine, Magod, Ben, Mazzei, Amelia, Mazarati, Jean-Baptiste, Noben, Jozef, Katwere, Michael, Parker, Rachel, Nsanzimana, Sabin, Wall, Kristin M, Sayinzoga, Felix, Tichacek, Amanda, Robinson, Cynthia, Hammoud, Niina, Priddy, Frances, Allen, Susan, Karita, Etienne“…BACKGROUND: From 2019 to 2021, Rwandan residents of the border with the Democratic Republic of the Congo were offered the Ad26.ZEBOV (adenovirus type 26 vector vaccine encoding Ebola virus glycoprotein) and MVA-BN-Filo (modified vaccinia virus Ankara vector vaccine, encoding glycoproteins from Ebola, Sudan, Marburg, and nucleoprotein from Tai Forest viruses) Ebola vaccine regimen. …”
Publicado 2022
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819por Zaeck, Luca M., Lamers, Mart M., Verstrepen, Babs E., Bestebroer, Theo M., van Royen, Martin E., Götz, Hannelore, Shamier, Marc C., van Leeuwen, Leanne P. M., Schmitz, Katharina S., Alblas, Kimberley, van Efferen, Suzanne, Bogers, Susanne, Scherbeijn, Sandra, Rimmelzwaan, Guus F., van Gorp, Eric C. M., Koopmans, Marion P. G., Haagmans, Bart L., GeurtsvanKessel, Corine H., de Vries, Rory D.“…In July 2022, the ongoing monkeypox (MPX) outbreak was declared a public health emergency of international concern. Modified vaccinia Ankara—Bavarian Nordic (MVA-BN, also known as Imvamune, JYNNEOS or Imvanex) is a third-generation smallpox vaccine that is authorized and in use as a vaccine against MPX. …”
Publicado 2022
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820por Wolff Sagy, Yael, Zucker, Roy, Hammerman, Ariel, Markovits, Hila, Arieh, Noa Gur, Abu Ahmad, Wiessam, Battat, Erez, Ramot, Noga, Carmeli, Guy, Mark-Amir, Avner, Wagner-Kolasko, Gal, Duskin-Bitan, Hadar, Yaron, Shlomit, Peretz, Alon, Arbel, Ronen, Lavie, Gil, Netzer, Doron“…The smallpox and mpox vaccine (JYNNEOS; Modified Vaccinia Ankara-Bavarian Nordic; MVA-BN), provided as a two-dose regimen, is currently the primary vaccine utilized against mpox. …”
Publicado 2023
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