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921por Atasoy Karakas, Latife, Tugrul, Duygu, Sahin Uysal, Nihal, Esin, Sertac, Tokel, Niyazi Kursat, Terzi, Yunus Kasim“…Trial registration: This present prospective case–control study was conducted in Baskent University Hospital, Ankara, Turkey, between May 2020 and November 2021. …”
Publicado 2022
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922por Tekiner, Selda Ayşe, Çullas Ilarslan, Nisa Eda, Günay, Fatih, Ceyhun Peker, Gülsen Ayşe“…MATERIALS AND METHODS: This is a cross-sectional study and we aimed to reach all mothers with babies between 0 and 24 months of age who applied to the Healthy Child Care Policlinic of Ankara University Faculty of Medicine Hospital between July 1 and August 31, 2020 Questionnaires measuring the level of knowledge about COVID-19 disease and breast milk and questionnaires measuring anxiety levels were administered to mothers. …”
Publicado 2022
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923por Styles, Tiffany M., Gangadhara, Sailaja, Reddy, Pradeep B. J., Sahoo, Anusmita, Shiferaw, Ayalensh, Welbourn, Sarah, Kozlowski, Pamela A., Derdeyn, Cynthia A., Velu, Vijayakumar, Amara, Rama Rao“…Here, we compared the immunogenicity and efficacy of two modified vaccinia Ankara (MVA) vaccines based on variable loop 2 hotspot (V2 HS) optimized C.1086 envelope (Env) sequences, one expressing the membrane anchored gp150 (MVA-150) and the other expressing soluble uncleaved pre-fusion optimized (UFO) gp140 trimer (MVA-UFO) in a DNA prime/MVA boost approach against heterologous tier 2 SHIV1157ipd3N4 intrarectal challenges in rhesus macaques (RMs). …”
Publicado 2022
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924por Keskin, Müge, Polat, Sefika Burcak, Ates, İhsan, İzdes, Seval, Güner, Hatice Rahmet, Topaloglu, Oya, Ersoy, Reyhan, Cakır, Bekir“…Methods: Our retrospective study included 311 PCR-positive COVID-19 patients over the age of 18 who were hospitalized in Ankara City Hospital Infectious Diseases Department or Intensive Care Unit (ICU) between 15 March 2020 and 15 May 2020. …”
Publicado 2022
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925por El Kenawy, Ahmed M., Lopez-Moreno, Juan I., McCabe, Matthew F., Domínguez-Castro, Fernando, Peña-Angulo, Dhais, Gaber, Islam M., Alqasemi, Abduldaem S., Al Kindi, Khalifa M., Al-Awadhi, Talal, Hereher, Mohammed E., Robaa, Sayed M., Al Nasiri, Noura, Vicente-Serrano, Sergio M.“…Kuwait, Dubai, and Muscat), the megacities (e.g. Tehran, Ankara, and Istanbul) exhibited anomalous increases in the intensity of daytime SUHI, which may exceed 2 °C. …”
Publicado 2021
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926por Cohen, Kristen W., Fiore-Gartland, Andrew, Walsh, Stephen R., Yusim, Karina, Frahm, Nicole, Elizaga, Marnie L., Maenza, Janine, Scott, Hyman, Mayer, Kenneth H., Goepfert, Paul A., Edupuganti, Srilatha, Pantaleo, Giuseppe, Hutter, Julia, Morris, Daryl E., De Rosa, Stephen C., Geraghty, Daniel E., Robb, Merlin L., Michael, Nelson L., Fischer, Will, Giorgi, Elena E., Malhi, Harmandeep, Pensiero, Michael N., Ferrari, Guido, Tomaras, Georgia D., Montefiori, David C., Gilbert, Peter B., McElrath, M. Juliana, Haynes, Barton F., Korber, Bette T., Baden, Lindsey R.“…METHODS: This double-blind randomized trial enrolled 105 healthy HIV-uninfected adults who received 3 doses of either a trivalent global mosaic, a group M consensus (CON-S), or a natural clade B (Nat-B) gp160 env DNA vaccine followed by 2 doses of a heterologous modified vaccinia Ankara–vectored HIV-1 vaccine or placebo. We performed prespecified blinded immunogenicity analyses at day 70 and day 238 after the first immunization. …”
Publicado 2023
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927por Fathi, Anahita, Dahlke, Christine, Hardtke, Svenja, Mellinghoff, Sibylle C, Mayer, Leonie, Weskamm, Leonie M, Krähling, Verena, Müller-Kräuter, Helena, Ly, My L, Friedrich, Monika, Hesterkamp, Thomas J, Volz, Asisa, Sutter, Gerd, Becker, Stephan, Addo, Marylyn“…BACKGROUND: Recombinant Modified Vaccinia virus Ankara (MVA) is a replication-deficient viral vector platform with a favorable safety profile that is currently developed for multiple indications, including vaccines against emerging infections. …”
Publicado 2023
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928por Tameris, Michele D, Hatherill, Mark, Landry, Bernard S, Scriba, Thomas J, Snowden, Margaret Ann, Lockhart, Stephen, Shea, Jacqueline E, McClain, J Bruce, Hussey, Gregory D, Hanekom, Willem A, Mahomed, Hassan, McShane, Helen“…A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was designed to enhance the protective efficacy of BCG. …”
Publicado 2013
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929por Nadai, Yuka, Held, Kathrin, Joseph, Sarah, Ahmed, Mohamed I. M., Hoffmann, Verena S., Peterhoff, David, Missanga, Marco, Bauer, Asli, Joachim, Agricola, Reimer, Ulf, Zerweck, Johannes, McCormack, Sheena, Cope, Alethea V., Tatoud, Roger, Shattock, Robin J., Robb, Merlin Lee, Sandstroem, Eric G., Hoelscher, Michael, Maboko, Leonard, Bakari, Muhammad, Kroidl, Arne, Wagner, Ralf, Weber, Jonathan, Pollakis, Georgios, Geldmacher, Christof“…Both trials consisted of three immunizations with DNA, followed by two boosts with recombinant Modified Vaccinia Virus Ankara (MVA), either mediating secretion of gp120 (UK003SG) or the presentation of cell membrane bound gp150 envelopes (TMV01) from infected cells, and an additional two boosts with 5 μg of CN54gp140 protein adjuvanted with glucopyranosyl lipid adjuvant (GLA). …”
Publicado 2019
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930por Cox, Andrea L, Page, Kimberly, Melia, Michael, Veenhuis, Rebecca, Massaccesi, Guido, Osburn, William, Wagner, Katherine, Giudice, Linda, Stein, Ellen, Asher, Alice K, Vassilev, Ventzislav, Lin, Lan, Nicosia, Alfredo, Capone, Stefania, Scarselli, Elisa, Folgori, Antonella, Gorman, Richard, Chang, Soju, Wolff, Peter, Liang, T Jake, Ghany, Marc, Wierzbicki, Michael, Lum, Paula“…METHODS: In a randomized, multicenter, double-blind, placebo-controlled efficacy trial (NCT01436357), we evaluated a recombinant chimpanzee adenovirus 3 vector vaccine prime followed by a recombinant modified vaccinia Ankara boost, both encoding nonstructural proteins of HCV. …”
Publicado 2019
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931por Vázquez-Ramírez, Daniel, Genzel, Yvonne, Jordan, Ingo, Sandig, Volker, Reichl, Udo“…We here illustrate our strategy for production of the modified vaccinia Ankara (MVA) virus isolate MVA-CR19 in the avian suspension cell line AGE1.CR.pIX at HCD. …”
Publicado 2018
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932por Cappuccini, Federica, Bryant, Richard, Pollock, Emily, Carter, Lucy, Verrill, Clare, Hollidge, Julianne, Poulton, Ian, Baker, Megan, Mitton, Celia, Baines, Andrea, Meier, Armin, Schmidt, Guenter, Harrop, Richard, Protheroe, Andrew, MacPherson, Ruth, Kennish, Steven, Morgan, Susan, Vigano, Selena, Romero, Pedro J, Evans, Thomas, Catto, James, Hamdy, Freddie, Hill, Adrian V S, Redchenko, Irina“…METHODS: In this first-in-man study, VANCE, we evaluated a novel vaccination platform based on two replication-deficient viruses, chimpanzee adenovirus (ChAd) and MVA (Modified Vaccinia Ankara), targeting the oncofetal self-antigen 5T4 in early stage PCa. …”
Publicado 2020
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933por İnci, Aslı, Okur, İlyas, Tümer, Leyla, Biberoğlu, Gürsel, Öktem, Murat, Ezgü, Fatih“…Clinical data of 14 children with MPS VI who were followed up at the Department of Pediatrics of the Gazi University Faculty of Medicine in Ankara, Turkey were retrospectively collected from the patients’ medical records. …”
Publicado 2021
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934“…A statistically significant difference was found between the rates of catastrophic expenditures of the families living in Ankara and those who were admitted from other provinces for follow-up and treatment (p < 0.001). …”
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935por Hartnell, Felicity, Brown, Anthony, Capone, Stefania, Kopycinski, Jakub, Bliss, Carly, Makvandi-Nejad, Shokouh, Swadling, Leo, Ghaffari, Emma, Cicconi, Paola, Del Sorbo, Mariarosaria, Sbrocchi, Roberta, Esposito, Ilaria, Vassilev, Ventzislav, Marriott, Paula, Gardiner, Clair M., Bannan, Ciaran, Bergin, Colm, Hoffmann, Matthias, Turner, Bethany, Nicosia, Alfredo, Folgori, Antonella, Hanke, Tomáš, Barnes, Eleanor, Dorrell, Lucy“…We developed a novel vaccination regimen involving replication-defective and serologically distinct chimpanzee adenovirus (ChAd3, ChAd63) vector priming followed by modified vaccinia Ankara (MVA) boosts, for simultaneous delivery of HCV non-structural (NSmut) and HIV-1 conserved (HIVconsv) region immunogens. …”
Publicado 2019
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936por Green, Christopher A., Sande, Charles J., Scarselli, Elisa, Capone, Stefania, Vitelli, Alessandra, Nicosia, Alfredo, Silva-Reyes, Laura, Thompson, Amber J., de Lara, Catherine M., Taylor, Kathryn S., Haworth, Kathryn, Hutchings, Claire L., Cargill, Tamsin, Angus, Brian, Klenerman, Paul, Pollard, Andrew J.“…The replication-defective chimpanzee adenovirus (PanAd3-RSV) and modified vaccinia virus Ankara (MVA-RSV) vaccines were shown to be safe and immunogenic in young healthy adults. …”
Publicado 2019
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937por Bahar Özvarış, Şevkat, Güçiz Doğan, Bahar, Konşuk Ünlü, Hande, Aktuna, Gamze, İnandı, Tacettin, Kurt, A. Öner, Aydın, Neriman, Kutluk, M. Tezer“…The questionnaire and the Scale were pre-tested among 30 Syrian refugees in Ankara province. A total of 1254 refugees were participated into the main part of the study; 47 health-worker participants were excluded from the validity-reliability analysis. …”
Publicado 2021
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938“…MATERIAL AND METHODS: This prospective, open-label clinical phase-3 study was conducted at Ankara University Faculty of Medicine, Department of Ophthalmology between April 2019 and April 2021. …”
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939por Wang, Xiuli, Urak, Ryan, Walter, Miriam, Guan, Min, Han, Tianxu, Vyas, Vibhuti, Chien, Sheng-Hsuan, Gittins, Brenna, Clark, Mary C, Mokhtari, Sally, Cardoso, Angelo, Diamond, Don J, Zaia, John, Forman, Stephen J, Nakamura, Ryotaro“…We plan to initiate a clinical trial at City of Hope using CMV-CD19CAR T cells for patients with intermediate/high-grade B cell non-Hodgkin’s lymphoma immediately after autologous hematopoietic cell transplantation followed by vaccination with a novel CMV vaccine based on Modified Vaccinia Ankara (Triplex) 28 days and 56 days post-T cell infusion.…”
Publicado 2022
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940por Jones, Andrew T., Chamcha, Venkateswarlu, Kesavardhana, Sannula, Shen, Xiaoying, Beaumont, David, Das, Raksha, Wyatt, Linda S., LaBranche, Celia C., Stanfield-Oakley, Sherry, Ferrari, Guido, Montefiori, David C., Moss, Bernard, Tomaras, Georgia D., Varadarajan, Raghavan, Amara, Rama Rao“…Here, we tested the immunogenicity of cycP-gp120 in a protein prime/boost approach in rabbits and as a booster immunization to DNA/modified vaccinia Ankara (MVA)-vaccinated rabbits and rhesus macaques. …”
Publicado 2018
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