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121por Di Mario, Giuseppina, Soprana, Elisa, Gubinelli, Francesco, Panigada, Maddalena, Facchini, Marzia, Fabiani, Concetta, Garulli, Bruno, Basileo, Michela, Cassone, Antonio, Siccardi, Antonio, Donatelli, Isabella, Castrucci, Maria R.“…Methods: Modified vaccinia virus Ankara (MVA) expressing a headless HA (hlHA) of A/California/4/09 (CA/09) virus was used as a vaccine to immunize C57BL/6 mice. …”
Publicado 2017
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122por Florek, Kelsey R., Kamlangdee, Attapon, Mutschler, James P., Kingstad-Bakke, Brock, Schultz-Darken, Nancy, Broman, Karl W., Osorio, Jorge E., Friedrich, Thomas C.“…We recently constructed a “mosaic” hemagglutinin (HA) based on subtype 5 HA (H5) and designed to stimulate cellular and humoral immunity to multiple influenza virus subtypes. Modified vaccinia Ankara (MVA) expressing this H5 mosaic (MVA-H5M) protected mice against multiple homosubtypic H5N1 strains and a heterosubtypic H1N1 virus. …”
Publicado 2017
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123por Wong, Yik Chun, Croft, Sarah, Smith, Stewart A., Lin, Leon C. W., Cukalac, Tania, La Gruta, Nicole L., Drexler, Ingo, Tscharke, David C.“…While much of the pioneering work was done with virulent strains, such as Western Reserve (WR), attenuated strains such as modified vaccinia virus Ankara (MVA) are more realistic vectors for clinical use. …”
Publicado 2019
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124por Rall, Isabell, Amann, Ralf, Malberg, Sara, Herden, Christiane, Rubbenstroth, Dennis“…In previous studies we demonstrated a prime-boost vaccination regime using modified vaccinia virus Ankara (MVA) and Newcastle disease virus (NDV) constructs expressing the nucleoprotein and phosphoprotein of PaBV-4 (MVA/PaBV-4 and NDV/PaBV-4, respectively) to protect cockatiels (Nymphicus hollandicus) against experimental challenge infection. …”
Publicado 2019
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125por Jordan, Ingo, Horn, Deborah, Thiele, Kristin, Haag, Lars, Fiddeke, Katharina, Sandig, Volker“…Vectored vaccines based on highly attenuated modified vaccinia Ankara (MVA) are reported to be immunogenic, tolerant to pre-existing immunity, and able to accommodate and stably maintain very large transgenes. …”
Publicado 2019
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126por Malherbe, Delphine C., Domi, Arban, Hauser, Mary J., Meyer, Michelle, Gunn, Bronwyn M., Alter, Galit, Bukreyev, Alexander, Guirakhoo, Farshad“…We introduce a new vaccine platform against Marburg virus (MARV) combining the advantages of the immunogenicity of a highly attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conformation of virus-like particles (VLPs). …”
Publicado 2020
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127por Volkmann, Ariane, Williamson, Anna-Lise, Weidenthaler, Heinz, Meyer, Thomas P.H., Robertson, James S., Excler, Jean-Louis, Condit, Richard C., Evans, Eric, Smith, Emily R., Kim, Denny, Chen, Robert T.“…The Modified Vaccinia Ankara (MVA) vector system is being explored as a platform for development of multiple vaccines. …”
Publicado 2021
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128“…For this, the modified vaccinia virus Ankara (MVA) was compared to ASFV in terms of its susceptibility to disinfectants. …”
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129por Jiménez de Oya, Nereida, Pérez, Patricia, Blázquez, Ana-Belén, Escribano-Romero, Estela, Esteban, Mariano, Saiz, Juan-Carlos, García-Arriaza, Juan, Martín-Acebes, Miguel A.“…Therefore, anticipating the potential scenario of emergency vaccination against ZIKV in areas of Europe where WNV is endemic, in this investigation, we have evaluated the cross-reactivity between WNV and our previously developed ZIKV vaccine candidate based on modified vaccinia virus Ankara (MVA) vector expressing ZIKV structural proteins (MVA-ZIKV). …”
Publicado 2022
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130por Bella, Ángela, Arrizabalaga, Leire, Di Trani, Claudia Augusta, Cirella, Assunta, Fernandez-Sendin, Myriam, Gomar, Celia, Russo-Cabrera, Joan Salvador, Rodríguez, Inmaculada, González-Gomariz, José, Alvarez, Maite, Teijeira, Álvaro, Medina-Echeverz, José, Hinterberger, Maria, Hochrein, Hubertus, Melero, Ignacio, Berraondo, Pedro, Aranda, Fernando“…Recombinant-modified vaccinia virus Ankara (rMVA) is known to elicit potent antitumor immune responses in preclinical models due to its inherent ability to activate the innate immune system and the activation of adaptive responses mediated by the expression of tumor antigens and costimulus-providing molecules, such as CD40L and CD137L. …”
Publicado 2022
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131por Ozgurluk, Izzet, Tastekin, Burak, Yazkan Hira, Sila, Gungorer, Bulent, Hekimoglu, Yavuz, Keskin, Huseyin Levent, Keskin, Siddik, Asirdizer, Mahmut“…The current study’s objectives are to define the COVID-19 pandemic’s impact on physical IPV against pregnant women in Ankara. PATIENTS AND METHODS: During the one-year pre-pandemic and two-year pandemic, records of patients who sent by the judicial authorities to the Obstetrics and Gynecology Emergency Room (ER) at Ankara City Hospital were reviewed, and pregnant women who had been subjected to IPV were identified. …”
Publicado 2023
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132por Bollimpelli, Venkata S., Reddy, Pradeep B. J, Gangadhara, Sailaja, Charles, Tysheena P., Burton, Samantha L., Tharp, Gregory K., Styles, Tiffany M., Labranche, Celia C., Smith, Justin C., Upadhyay, Amit A., Sahoo, Anusmita, Legere, Traci, Shiferaw, Ayalnesh, Velu, Vijayakumar, Yu, Tianwei, Tomai, Mark, Vasilakos, John, Kasturi, Sudhir P., Shaw, George M., Montefiori, David, Bosinger, Steven E., Kozlowski, Pamela A., Pulendran, Bali, Derdeyn, Cynthia A., Hunter, Eric, Amara, Rama R.“…Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2 simian-human immunodeficiency virus (SHIV) challenges in female macaques. …”
Publicado 2023
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133por Ramchandani, Meena S, Berzkalns, Anna, Cannon, Chase A, Dombrowski, Julia C, Brown, Elizabeth, Chow, Eric J, Barash, Elizabeth, Pogosjans, Sargis, Smith, Daniel, Golden, Matthew R“…BACKGROUND: Data on modified Vaccinia Ankara (MVA) vaccine effectiveness against mpox in real-world settings are limited. …”
Publicado 2023
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134por Delaloye, Julie, Roger, Thierry, Steiner-Tardivel, Quynh-Giao, Le Roy, Didier, Knaup Reymond, Marlies, Akira, Shizuo, Petrilli, Virginie, Gomez, Carmen E., Perdiguero, Beatriz, Tschopp, Jürg, Pantaleo, Giuseppe, Esteban, Mariano, Calandra, Thierry“…Modified vaccinia virus Ankara (MVA) is an attenuated double-stranded DNA poxvirus currently developed as a vaccine vector against HIV/AIDS. …”
Publicado 2009
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135por Hessel, Annett, Schwendinger, Michael, Holzer, Georg W., Orlinger, Klaus K., Coulibaly, Sogue, Savidis-Dacho, Helga, Zips, Marie-Luise, Crowe, Brian A., Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel, Falkner, Falko G.“…The aim of this study was to evaluate the cross-protective potential of the hemagglutinins of five H5N1 strains of divergent clades using a live attenuated modified vaccinia Ankara (MVA) vector vaccine. METHODOLOGY/PRINCIPAL FINDINGS: The replication-deficient MVA virus was used to express influenza hemagglutinin (HA) proteins. …”
Publicado 2011
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136por Bauer, A, Podola, L, Haule, A, Sudi, L, Nilsson, C, Mann, P, Missanga, M, Kaluwa, B, Maboko, L, Lueer, C, Mwakatima, M, Aboud, S, Bakari, M, Currier, J, Robb, M, Joseph, S, McCormack, S, Lyamuya, E, Wahren, B, Sandström, E, Biberfeld, G, Hoelscher, M, Kroidl, A, Geldmacher, CEnlace del recurso
Publicado 2012
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137por Wennier, Sonia T., Brinkmann, Kay, Steinhäußer, Charlotte, Mayländer, Nicole, Mnich, Claudia, Wielert, Ursula, Dirmeier, Ulrike, Hausmann, Jürgen, Chaplin, Paul, Steigerwald, Robin“…Modified vaccinia virus Ankara (MVA) has been shown to be suitable for the generation of experimental vaccines against cancer and infectious diseases, eliciting strong humoral and cellular immune responses. …”
Publicado 2013
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138por van den Doel, Petra, Volz, Asisa, Roose, Jouke M., Sewbalaksing, Varsha D., Pijlman, Gorben P., van Middelkoop, Ingeborg, Duiverman, Vincent, van de Wetering, Eva, Sutter, Gerd, Osterhaus, Albert D. M. E., Martina, Byron E. E.“…We have constructed recombinant Modified Vaccinia Ankara (MVA) expressing E3E2, 6KE1, or the entire CHIKV envelope polyprotein cassette E3E26KE1. …”
Publicado 2014
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139por Stylianou, E., Griffiths, K.L., Poyntz, H.C., Harrington-Kandt, R., Dicks, M.D., Stockdale, L., Betts, G., McShane, H.“…A replication-deficient chimpanzee adenovirus expressing Ag85A (ChAdOx1.85A) was assessed, both alone and in combination with modified vaccinia Ankara also expressing Ag85A (MVA85A), for its immunogenicity and protective efficacy against a Mycobacterium tuberculosis (M.tb) challenge in mice. …”
Publicado 2015
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140por Scurr, Martin, Pembroke, Tom, Bloom, Anja, Roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard, Brewster, Alison, Jones, Robert, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa, Hills, Robert, Gallimore, Awen, Godkin, Andrew“…Preliminary data using modified vaccinia Ankara–5T4 (MVA-5T4) in mCRC demonstrated that it safely induced serologic and T-cell responses. …”
Publicado 2017
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