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61“…In conclusion, this is the first study to develop a (genetic) obesity index and employ systems genetics in a porcine model to provide important insights into the complex genetic architecture associated with obesity and many biological pathways that underlie it.…”
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62por Huisman, André, Ploeger, Lennert S., Dullens, Hub F. J., Poulin, Neal, Grizzle, William E., van Diest, Paul J.“…The aim of this study was to develop 3D texture features that quantitatively describe changes in chromatin architecture associated with malignancy using CLSM images. …”
Publicado 2005
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63Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasiapor Nardiello, Claudio, Mižíková, Ivana, Silva, Diogo M., Ruiz-Camp, Jordi, Mayer, Konstantin, Vadász, István, Herold, Susanne, Seeger, Werner, Morty, Rory E.“…Thus, a state-of-the-art BPD animal model that recapitulates the two histopathological hallmark perturbations to lung architecture associated with BPD is described. The model presented here, where injurious stimuli have been systematically evaluated, provides a most promising approach for the development of new strategies to drive postnatal lung maturation in affected infants.…”
Publicado 2017
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64por Kanduri, Chakravarthi, Pavlović, Milena, Scheffer, Lonneke, Motwani, Keshav, Chernigovskaya, Maria, Greiff, Victor, Sandve, Geir K“…RESULTS: To identify those scenarios where a baseline ML method is able to perform well for AIRR classification, we generated a collection of synthetic AIRR benchmark data sets encompassing a wide range of data set architecture-associated and immune state–associated sequence patterns (signal) complexity. …”
Publicado 2022
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65por Zhao, Mei, Yang, Ju-Xiang, Mao, Tian-Yu, Zhu, Huan-Huan, Xiang, Lin, Zhang, Jie, Chen, Long-Qing“…In addition, 34 plant architecture-associated InDel markers were developed and verified in the remaining 11 LA and 12 SA lotus plant architecture representatives. …”
Publicado 2018
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66por Shen, Sipeng, Wei, Yongyue, Li, Yi, Duan, Weiwei, Dong, Xuesi, Lin, Lijuan, You, Dongfang, Tardon, Adonina, Chen, Chu, Field, John K., Hung, Rayjean J., Liu, Geoffrey, Zhu, Dakai, Amos, Christopher I., Su, Li, Zhao, Yang, Hu, Zhibin, Shen, Hongbing, Zhang, Ruyang, Chen, Feng, Christiani, David C.“…This study provides important insights into the genetic architecture associated with long-term former smoking NSCLC.…”
Publicado 2021
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67por Shah, Ravi V., Abbasi, Siddique A., Neilan, Tomas G., Hulten, Edward, Coelho‐Filho, Otavio, Hoppin, Alison, Levitsky, Lynne, de Ferranti, Sarah, Rhodes, Erinn T., Traum, Avram, Goodman, Elizabeth, Feng, Henry, Heydari, Bobak, Harris, William S., Hoefner, Daniel M., McConnell, Joseph P., Seethamraju, Ravi, Rickers, Carsten, Kwong, Raymond Y., Jerosch‐Herold, Michael“…CONCLUSIONS: Obese adolescents (particularly those with T2D) have subclinical alterations in myocardial tissue architecture associated with inflammation and insulin resistance. …”
Publicado 2013
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68por Kaldenbach, Michaela, Cubero, Francisco Javier, Erschfeld, Stephanie, Liedtke, Christian, Trautwein, Christian, Streetz, Konrad“…Concomitant with these findings, the histological examination elicited an improved liver tissue architecture associated with significantly lower levels of apoptosis, decreased proliferation and a lesser amount of liver fibrogenesis. …”
Publicado 2014
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69por Stanitsas, Panagiotis, Cherian, Anoop, Morellas, Vassilios, Tejpaul, Resha, Papanikolopoulos, Nikolaos, Truskinovsky, Alexander“…Material and Methods: We start with a patch level descriptor, termed Covariance-Kernel Descriptor (CKD), capable of compactly describing tissue architectures associated with carcinomas. To leverage the recognition capability of the CKDs to larger slide regions, we resort to a multiple instance learning framework. …”
Publicado 2020
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70por Mohanty, Bijayalaxmi“…The aim was to identify the correlation between promoter architecture, associated with transcriptional and hormonal regulation, in diverse genotype groups of rice that have different rates of coleoptile elongation. …”
Publicado 2021
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71“…Our results showed interspecific differences and suggest ontogenetic plasticity of the retinal architecture associated with changes in the niche occupied by viperid snakes, and highlight the importance of the retinal topography for visual ecology and behavior of snakes.…”
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72por Ye, Shenhua, Yan, Lei, Ma, Xiaowei, Chen, Yanping, Wu, Lumei, Ma, Tiantian, Zhao, Lun, Yi, Bin, Ma, Chaozhi, Tu, Jinxing, Shen, Jinxiong, Fu, Tingdong, Wen, Jing“…There, further analysis showed that genes involved in plant hormone biosynthesis and signal transduction, cell structure, and the phenylpropanoid pathway might play a pivotal role in the morphogenesis of plant architecture. Association analysis of BSA-Seq and RNA-Seq suggested that seven DEGs involved in plant hormone signal transduction and a WUSCHEL-related homeobox (WOX) gene (BnaA01g01910D) might be candidate genes responsible for the dwarf and compact phenotype in 4942C-5. …”
Publicado 2022
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73por Chen, Limiao, Yang, Hongli, Fang, Yisheng, Guo, Wei, Chen, Haifeng, Zhang, Xiaojuan, Dai, Wenjun, Chen, Shuilian, Hao, Qingnan, Yuan, Songli, Zhang, Chanjuan, Huang, Yi, Shan, Zhihui, Yang, Zhonglu, Qiu, Dezhen, Liu, Xiaorong, Tran, Lam‐Son Phan, Zhou, Xinan, Cao, Dong“…Stable GmMYB14‐overexpressing (GmMYB14‐OX) transgenic soybean plants displayed a semi‐dwarfism and compact plant architecture associated with decreased cell size, resulting in a decrease in plant height, internode length, leaf area, leaf petiole length and leaf petiole angle, and improved yield in high density under field conditions. …”
Publicado 2020
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74por Ziebell, Jenna M, Taylor, Samuel E, Cao, Tuoxin, Harrison, Jordan L, Lifshitz, Jonathan“…Here, we describe the time course, location, and surrounding architecture associated with rod microglia following experimental diffuse traumatic brain injury (TBI). …”
Publicado 2012
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75“…It exhibits mixed architectures associated with distinctive immunophenotype and recurrent KRAS and PIK3CA mutations, supporting classified as of Müllerian origin with mesonephric differentiation.…”
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76por Lee, Eunice Y., Choi, Wonson, Burkholder, Adam B., Perera, Lalith, Mack, Jasmine A., Miller, Frederick W., Fessler, Michael B., Cook, Donald N., Karmaus, Peer W. F., Nakano, Hideki, Garantziotis, Stavros, Madenspacher, Jennifer H., House, John S., Akhtari, Farida S., Schmitt, Charles S., Fargo, David C., Hall, Janet E., Motsinger-Reif, Alison A.“…The etiology of asthma is complex and involves multiple factors, including the environment and genetics, especially the distinct genetic architecture associated with ancestry. Compared to early-onset asthma, little is known about genetic predisposition to late-onset asthma. …”
Publicado 2023
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77por Gomes, Luciana Rodrigues, Rocha, Clarissa Ribeiro Reily, Martins, Davi Jardim, Fiore, Ana Paula Zen Petisco, Kinker, Gabriela Sarti, Bruni-Cardoso, Alexandre, Menck, Carlos Frederico Martins“…Altogether, our results demonstrate that 3D-cell architecture-associated resistance to cisplatin is due to an efficient induction of REV3L and TLS, dependent of ATR. …”
Publicado 2019
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78por Chang, Hao-Xun, Brown, Patrick J., Lipka, Alexander E., Domier, Leslie L., Hartman, Glen L.“…The goal of this study was to describe the genetic architecture associated with sensitivity to Tobacco ringspot virus (TRSV) infection in the USDA Soybean Germplasm Collection. …”
Publicado 2016
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