“…Anoikis-related genes were obtained from the Molecular Signatures Database and Pearson correlation analysis was performed to identify the anoikis-related lncRNAs (ARLs). We performed machine learning algorithms, including Univariate Cox regression and Least Absolute Shrinkage and Selection Operator (Lasso) analyses on the ARLs to build the OS-score and OS-signature. …”
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“…Despite highly active antiretroviral therapy (HAART), AIDS related lymphoma (ARL) occurs at a significantly higher rate in patients infected with the Human Immunodeficiency Virus (HIV) than in the general population. …”
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“…Transcription of esxA was strongly upregulated upon either sarA or sigB inactivation, but decreased in agr, arlR and spoVG single mutants, suggesting that agr, ArlR and SpoVG are able to increase esxA transcription and relieve the repressing effect of the σ(B)-controlled SarA on esxA. …”
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“…Thus, downregulation of arlRS might partially compensate for the relaxing effect of novobiocin. …”
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“…PATIENTS AND METHODS: Data of seven male and one female HIV+ patients with ARL was collected and informed consent was obtained. …”
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“…RESULTS: Time-lapse imaging of Arl13b:GFP(+) cilia revealed their dynamic behaviors, including distal tip excision into the extracellular milieu. …”
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“…Acute relative lymphopenia (ARL) was expressed by the nadir-PLC/baseline-PLC ratio < 0.5. …”
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“…These findings demonstrate that endolysosomal fusion is a critical determinant of the amount of exosome secretion and suggest that suppression of the BORC–ARL8–HOPS pathway could be used to boost exosome yields in biotechnology applications.…”
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“…We assessed the performance of the control chart using Average Run Length (ARL) as the evaluation metric. To compute the ARL properties, we adopted the Monte-Carlo simulation method. …”
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“…Linear regression models comparing the PG-Tx and ARL groups revealed that the maximum reduction in total motility and concentration was in men with germ-cell tumors, whereas the minimum reduction was in hematological tumors. …”
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“…In this study, a total of 391 rice (Oryz asativa L.) accessions were used to perform a genome-wide association study (GWAS) on three root-related traits in rice, including main root length (MRL), average root length (ARL), and total root number (TRN). As a result, 13 quantitative trait loci (QTLs) (qMRL1.1, qMRL1.2, qMRL3.1, qMRL3.2, qMRL3.3, qMRL4.1, qMRL7.1, qMRL8.1, qARL1.1, qARL9.1, qTRN9.1, qTRN9.2, and qTRN11.1) significantly associated with the three traits were identified, among which three (qMRL3.2, qMRL4.1 and qMRL8.1) were overlapped with OsGNOM1, OsARF12 and qRL8.1, respectively, and ten were novel QTLs. …”
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“…Arf family members, including Arf-like (Arl) proteins have been implicated in several essential cellular functions, like cell spreading and migration. …”
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“…Among HIV-associated cancers, acquired immune deficiency syndrome-related lymphoma (ARL) is still the most common condition and the leading cause of HIV/AIDS-related deaths. …”
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“…Furthermore, the expected ARL (EARL) is a method for evaluating the performance of control charts beyond a specific range of shift sizes. …”
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“…There is therefore a need to develop a method which is capable of automatically transforming ARL kinetic information into more detailed MRL rate constants. …”
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“…The methylation levels of IDH2 and ARL14 were appreciably related to the survival results. …”
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“…Our results assign Rab2a and Rab7 to LEs and Arl8 and BORC to LYSs and show that HOPS drives LE-LYS fusion by bridging late endosomal Rab2a with lysosomal BORC-anchored Arl8. …”
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“…Two evaluations of the handpiece were performed: the apical accuracy during the auto reverse function (ARL) and the apex locator function (EL) alone. The ARL function of the handpiece gave acceptable results. …”
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“…The transport of these proteins involves the BBSome, an eight-membered protein complex that is recruited to ciliary membranes by the G-protein Arl6. BBSome malfunction leads to Bardet-Biedl syndrome, a ciliopathy with severe consequences. …”
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“…ARL6 recognizes a composite binding site formed by BBS1 and BBS7 that is occluded in the inactive state. …”
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