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561“…EAAC1 protein content in liver homogenates (n = 8) decreased in finished vs. growing steers, whereas GTRAP3-18 and ARL6IP1 content increased and GLT-1 content did not change. …”
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562por Kubota, Shigehisa, Yoshida, Tetsuya, Kageyama, Susumu, Isono, Takahiro, Yuasa, Takeshi, Yonese, Junji, Kushima, Ryoji, Kawauchi, Akihiro, Chano, Tokuhiro“…However, it is essential to develop an accurate system to allow better patient selection for optimal treatment strategies. ARL4C, ECT2, SOD2, and STEAP3 are novel molecular biomarkers identified in earlier studies as survival-related genes by comprehensive analyses of 43 primary RCC tissues and RCC cell lines. …”
Publicado 2020
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563“…Pay-for-performance programs to incentivize quality are on the rise nationally (Werner, Konetzka, & Polsky, 2013 & Arling, Job, & Cooke, 2009). Kansas initiated a Medicaid P4P program to incentivize person-centered care (PCC) beginning in 2012 called PEAK 2.0. …”
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564por Wang, Qiwei, Zhang, Xulin, Qin, Tingfeng, Wang, Dongni, Lin, Xiaoshan, Zhu, Yuanyuan, Tan, Haowen, Zhao, Lanqin, Li, Jing, Lin, Zhuoling, Lin, Haotian, Chen, Weirong“…We assessed the involvement of the ARL14EP gene in patients with and without severe lens abnormalities and found that its deletion may worsen the lens abnormalities in these patients.…”
Publicado 2022
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565“…BACKGROUND: HIV infection is reported to be associated with some malignant lymphomas (ML) so called AIDS-related lymphomas (ARL), with an aggressive behavior and poor prognosis. …”
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566por Lee, Kristen L, Guevarra, Marie D, Nguyen, An M, Chua, Mardonn C, Wang, Yingxiao, Jacobs, Christopher R“…RESULTS: Here, we report the first measurements of Ca(2+) signaling within osteocyte primary cilia using a FRET-based biosensor fused to ARL13B. We show that fluid flow induces Ca(2+) increases in osteocyte primary cilia which depend on both intracellular Ca(2+) release and extracellular Ca(2+) entry. …”
Publicado 2015
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567“…In contrast, the lysosomal GTPase Gie/Arl8 is only required for late endosome-lysosome fusion, but not for the delivery of LAMP to the endocytic pathway. …”
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568por Li, Chunmei, Jensen, Victor L., Park, Kwangjin, Kennedy, Julie, Garcia-Gonzalo, Francesc R., Romani, Marta, De Mori, Roberta, Bruel, Ange-Line, Gaillard, Dominique, Doray, Bérénice, Lopez, Estelle, Rivière, Jean-Baptiste, Faivre, Laurence, Thauvin-Robinet, Christel, Reiter, Jeremy F., Blacque, Oliver E., Valente, Enza Maria, Leroux, Michel R.“…Consistent with a critical role in ciliary gate function, CEP-290 prevents inappropriate entry of membrane-associated proteins into cilia and keeps ARL-13 (Arl13b) from leaking out of cilia via the TZ. …”
Publicado 2016
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569
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570por Zimmerman, David R., Karon, Sarita L., Arling, Greg, Clark, Brenda Ryther, Collins, Ted, Ross, Richard, Sainfort, FrançoisEnlace del recurso
Publicado 1995
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571por Ambroggio, Ernesto E., Sillibourne, James, Antonny, Bruno, Manneville, Jean-Baptiste, Goud, Bruno“…Arfaptin2 contains a Bin/Amphiphysin/Rvs (BAR) domain and directly interacts with proteins of the Arf/Arl family in their active GTP-bound state. It has been proposed that BAR domains are able to sense membrane curvature and to induce membrane tubulation. …”
Publicado 2013
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572por Russo, Riccardo, Chae, Richard, Mukherjee, Somdatta, Singleton, Eric J., Occi, James L., Kadouri, Daniel E., Connell, Nancy D.“…In this study, we have examined the ability of Bdellovibrio bacteriovorus (B. bacteriovorus) strain 109J, HD100 and Micavibrio aeruginosavorus (M. aeruginosavorus) ARL-13 to prey on a variety of Select Agents. Our findings demonstrate that B. bacteriovorus and M. aeruginosavorus are able to prey efficiently on Yersinia pestis and Burkholderia mallei. …”
Publicado 2015
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573por Tamura, Ryo, Nakaoka, Hirofumi, Yoshihara, Kosuke, Mori, Yutaro, Yachida, Nozomi, Nishikawa, Nobumichi, Motoyama, Teiichi, Okuda, Shujiro, Inoue, Ituro, Enomoto, Takayuki“…Next, we performed RNA sequencing of the tumor sample and identified two in‐frame fusion transcripts: MXD4–NUTM1 and ARL6–POT1. Most NUTM1 exons were retained in the MXD4–NUTM1 fusion transcript, and we confirmed an increase in NUTM1 mRNA and protein expression in tumor tissue. …”
Publicado 2018
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574por Klink, Björn Udo, Gatsogiannis, Christos, Hofnagel, Oliver, Wittinghofer, Alfred, Raunser, Stefan“…The complex adopts a conformation that is open for binding to membrane-associated GTPase Arl6 and a large positively charged patch likely strengthens the interaction with the membrane. …”
Publicado 2020
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575por Winzker, Michael, Friese, Alexandra, Koch, Uwe, Janning, Petra, Ziegler, Slava, Waldmann, Herbert“…However, allosteric inhibitor release from PDEδ by the Arl2/3 GTPases limits their application. We describe the development of new proteolysis‐targeting chimeras (PROTACs) that efficiently and selectively reduce PDEδ levels in cells through induced proteasomal degradation. …”
Publicado 2020
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576por Ghosh, Sourish, Dellibovi-Ragheb, Teegan A., Kerviel, Adeline, Pak, Eowyn, Qiu, Qi, Fisher, Matthew, Takvorian, Peter M., Bleck, Christopher, Hsu, Victor W., Fehr, Anthony R., Perlman, Stanley, Achar, Sooraj R., Straus, Marco R., Whittaker, Gary R., de Haan, Cornelis A.M., Kehrl, John, Altan-Bonnet, Grégoire, Altan-Bonnet, Nihal“…This unconventional egress is regulated by the Arf-like small GTPase Arl8b and can be blocked by the Rab7 GTPase competitive inhibitor CID1067700. …”
Publicado 2020
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577“…In this paper, we present the performance of a modified exponentially weighted moving average (modified EWMA) control chart to detect small changes when the observations are autocorrelated with exponential white noise through the average run length evaluated (ARLs) by explicit formulas. The accuracy of the solution was verified with a numerical integral equation method. …”
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578por Chassefeyre, Romain, Chaiamarit, Tai, Verhelle, Adriaan, Novak, Sammy Weiser, Andrade, Leonardo R., Leitão, André D. G., Manor, Uri, Encalada, Sandra E.“…We found that the small endolysosomal guanosine triphosphatase (GTPase) Arl8b recruits kinesin-1 and Vps41 (HOPS) onto endosomes carrying misfolded mutant PrP to promote their axonal entry and homotypic fusion toward aggregation inside enlarged endomembranes that we call endoggresomes. …”
Publicado 2021
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579por Verweij, Frederik J., Bebelman, Maarten P., George, Anna E., Couty, Mickael, Bécot, Anaïs, Palmulli, Roberta, Heiligenstein, Xavier, Sirés-Campos, Julia, Raposo, Graça, Pegtel, Dirk Michiel, van Niel, Guillaume“…These compartments undergo a Rab7a/Arl8b/Rab27a GTPase cascade to fuse with the PM. …”
Publicado 2022
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580por Thomas, Matthew C., Arling, Victoria, Goji, Noriko, Janzen, Timothy W., Duceppe, Marc-Olivier, Mathews, Amit, Carrillo, Catherine, Amoako, Kingsley K.Enlace del recurso
Publicado 2018
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