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76441por Koopman, Daniëlle, van Dalen, Jorn A., Arkies, Hester, Oostdijk, Ad H. J., Francken, Anne Brecht, Bart, Jos, Slump, Cornelis H., Knollema, Siert, Jager, Pieter L.“…BACKGROUND: We evaluated the diagnostic implications of a small-voxel reconstruction for lymph node characterization in breast cancer patients, using state-of-the-art FDG-PET/CT. We included 69 FDG-PET/CT scans from breast cancer patients. …”
Publicado 2018
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76442por Chan, Derek J., Furner, Virginia, Smith, Don E., Dronavalli, Mithilesh, Bopage, Rohan I., Post, Jeffrey J., Bhardwaj, Anjali K.“…Five predictors of poor health outcomes were identified: (1) co-morbidity score was associated with hospitalisation (odds ratio, OR 1.58; 95% CI 1.01–2.46; p = 0.044); (2) mental health score was associated with hospitalisation (OR 1.79; 95% CI 1.22–2.62; p = 0.003) and poor adherence to ART (OR 2.34; 95% CI 1.52–3.59; p = 0.001); (3) social issues score was associated with genotypic resistance (OR 2.61; 95% CI 1.48–4.59; p = 0.001), co-morbidity score (OR 1.69; 95% CI 1.24–2.3; p = 0.001) and hospitalisation (OR 1.72; 95% CI 1.1–2.7; p = 0.018); (4) body mass index < 20 was associated with genotypic resistance (OR 6.25; 95% CI 1.49–26.24; p = 0.012); and (5) Medicare eligibility was associated with co-morbidity score (OR 2.21; 95% CI 1.24–3.95; p = 0.007). …”
Publicado 2018
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76443por Ségéral, Olivier, Nerrienet, Eric, Neth, Sansothy, Spire, Bruno, Khol, Vohith, Ferradini, Laurent, Sarun, Saramony, Mom, Chandara, Ngin, Sopheak, Charpentier, Charlotte, Men, Pagnaroat, Mora, Marion, Mean Chhi, Vun, Ly, Penhsun, Saphonn, Vonthanak“…CONCLUSION: This study reports high rate of virological suppression of second-line regimen and importance of adherence boosting prior to deciding any change of ART regimen. Genotype resistance tests appear necessary to guide decisions. …”
Publicado 2018
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76444por Oladele, Edward A, Badejo, Okikiolu A, Obanubi, Christopher, Okechukwu, Emeka F, James, Ezekiel, Owhonda, Golden, Omeh, Onuche I, Abass, Moyosola, Negedu‐Momoh, Olubunmi R, Ojehomon, Norma, Oqua, Dorothy, Raj‐Pandey, Satish, Khamofu, Hadiza, Torpey, Kwasi“…Model B cluster identified 32 HIV‐positives (95% CI: 25.00 to 40.51) and initiated 8 HIV‐positives on antiretroviral treatment (95% CI: 5.54 to 10.33). After commART introduction, Model A cluster showed an immediate significant increase in 744 HIV‐positive persons (p = 0.00, 95% CI: 360.35 to 1127.77) and 560 HIV‐positives initiated on treatment (p = 0.00, 95% CI: 260.56 to 859.64). …”
Publicado 2018
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76445“…Health care workers and cervical cancer prevention and control program coordinators and implementers need to provide counseling services for all Anti-retroviral Therapy(ART) care attendants. So as to explore the root causes for the low utilization of precancerous stage of cervical Ca screening service, conducting a study on the supply side with a qualitative component is mandatory. …”
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76446por Rangaraju, Srikant, Dammer, Eric B., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Betarbet, Ranjita, Duong, Duc M., Webster, James A., Hales, Chadwick M., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.“…Transcriptomic studies of acutely-isolated microglia have provided novel insights into their molecular and functional diversity in homeostatic and neurodegenerative disease states. State-of-the-art mass spectrometry methods can comprehensively characterize proteomic alterations in microglia in neurodegenerative disorders, potentially providing novel functionally relevant molecular insights that are not provided by transcriptomics. …”
Publicado 2018
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76447por Sisay, Mekonnen, Bute, Dida, Edessa, Dumessa, Mengistu, Getnet, Amare, Firehiwot, Gashaw, Tigist, Bihonegn, Temesgen“…Greater proportion of patients started CPT prior to initiating antiretroviral therapy (ART). Most of the patients took CPT for greater than 6 months. …”
Publicado 2018
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76448por Cherutich, Peter, Farquhar, Carey, Wamuti, Beatrice, Otieno, Felix A., Ng’ang’a, Ann, Mutiti, Peter Maingi, Macharia, Paul, Sambai, Betsy, Bukusi, David, Levin, Carol“…Over the five years, the upper-bound budget impact of nurse-model was US$ 1,767,863, 63% and 35% of which were accounted for by aPS costs and ART costs, respectively. The CHW model incurred an upper-bound incremental cost of US$ 1,258,854, which was 71.2% lower than the nurse-based model. …”
Publicado 2018
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76449por Michiels, Sarah, van der Wal, Annemarie Christien, Nieste, Evelien, Van de Heyning, Paul, Braem, Marc, Visscher, Corine, Topsakal, Vedat, Gilles, Annick, Jacquemin, Laure, Hesters, Marianne, De Hertogh, Willem“…By evaluating the effect of state-of-the-art TMD treatment on tinnitus complaints, we can investigate the usefulness of TMD treatment in patients with somatic tinnitus. …”
Publicado 2018
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76450por Technau, Karl‐Günter, Mazanderani, Ahmad Haeri, Kuhn, Louise, Hans, Lucia, Strehlau, Renate, Abrams, Elaine J., Conradie, Martie, Coovadia, Ashraf, Mbete, Ndileka, Murnane, Pamela M, Patel, Faeezah, Shiau, Stephanie, Tiemessen, Caroline T., Sherman, Gayle G.“…Introduction: HIV‐1 polymerase chain reaction (PCR) testing at birth aims to facilitate earlier initiation of antiretroviral therapy (ART) for HIV‐infected neonates. Data from two years of universal birth testing implementation in a high‐burden South African urban setting are presented to demonstrate the prevalence and outcomes of diagnostic challenges in this context. …”
Publicado 2017
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76451por Silver, Nicholas, Paynter, Mary, McAllister, Georgina, Atchley, Maureen, Sayir, Christine, Short, John, Winner, Dane, Alouani, David J., Sharkey, Freddie H., Bergefall, Kicki, Templeton, Kate, Carrington, David, Quiñones-Mateu, Miguel E.“…George’s University Hospitals Healthcare NHS Foundation Trust (London) and at NHS Lothian (Edinburgh), to characterize minority HIV-1 variants in 109 plasma samples from ART-naïve or -experienced individuals. RESULTS: Although subtype B HIV-1 strains were highly prevalent (44%, 48/109), most individuals were infected with non-B subtype viruses (i.e., A1, A2, C, D, F1, G, CRF02_AG, and CRF01_AE). …”
Publicado 2018
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76452por Dirajlal-Fargo, Sahera, Kulkarni, Manjusha, Sattar, Abdus, Funderburg, Nicholas, McComsey, Grace A“…METHODS: We conducted a nested study within in the SATURN-HIV trial in which 147 HIV+ adults on stable antiretroviral therapy (ART), were virally suppressed, and had an LDL-cholesterol level <130 mg/dL were randomized to 10 mg daily rosuvastatin or placebo. …”
Publicado 2018
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76453por Anson, Ryan, Hall, Christopher, Ivans, Erica, Vassily, Kara, Shaieb, Annette, Berrol, Ronn, Potts, Brian, Bures, Erin“…All 12 patients with AHI initiated anti-retroviral therapy (ART) within five to 96 hours of their preliminary positive test result. …”
Publicado 2018
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76454por Purswani, Murli, Jacobson, Denise, Kopp, Jeffrey, Dyke, Russell Van, DiMeglio, Linda, Yao, Tzy-Jyun, Miller, Tracie, Siberry, George“…METHODS: Among a subset of HEU children in the multicenter (United States and Puerto Rico) observational Surveillance Monitoring for ART Toxicities (SMARTT) Cohort study, we enrolled neonates (≥36 weeks gestational age) of HIV+ mothers who took TDF for ≥8 weeks in the third trimester (TDF+) or no TDF in pregnancy (TDF-). …”
Publicado 2018
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76455por Wohl, David Alain, Brinson, Cynthia, Hicks, Charles, Shalit, Peter, Hardy, W David, Carter, Jeffrey, Simone, Laura, Sapir, Tamar“…RESULTS: Significant improvements were seen in sexually transmitted infection (STI) screening, and patient counseling on sexual risk, pre-exposure prophylaxis (PrEP), and antiretroviral therapy (ART). Documentation of several health maintenance measures improved significantly. …”
Publicado 2018
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76456“…Our deep learning model achieved state-of-the-art results (F1=65.9%), which is significantly higher than that (F1=61.7%) of the best system in the MADE1.0 challenge. …”
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76457por Caminiti, Silvia Paola, Sala, Arianna, Iaccarino, Leonardo, Beretta, Luca, Pilotto, Andrea, Gianolli, Luigi, Iannaccone, Sandro, Magnani, Giuseppe, Padovani, Alessandro, Ferini-Strambi, Luigi, Perani, Daniela“…The utility of [18F]FDG-PET in dementia with Lewy bodies (DLB) needs further validation by considering large samples of patients and disease comparisons and applying state-of-the-art statistical methods. Here, we aimed to provide an extensive validation of the [18F]FDG-PET metabolic signatures in supporting DLB diagnosis near the first clinical assessment, which is characterized by high diagnostic uncertainty, at the single-subject level. …”
Publicado 2019
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76458por Bahendeka, Silver, Kaushik, Ramaiya, Swai, Andrew Babu, Otieno, Fredrick, Bajaj, Sarita, Kalra, Sanjay, Bavuma, Charlotte M., Karigire, Claudine“…To date, insulin therapy remains the cornerstone of diabetes management; but the art of injecting insulin is still poorly understood in many health facilities. …”
Publicado 2019
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76459por Fizeșan, Ionel, Cambier, Sébastien, Moschini, Elisa, Chary, Aline, Nelissen, Inge, Ziebel, Johanna, Audinot, Jean-Nicolas, Wirtz, Tom, Kruszewski, Marcin, Pop, Anca, Kiss, Béla, Serchi, Tommaso, Loghin, Felicia, Gutleb, Arno C.“…The alveolar model was exposed to 0.05, 0.5 and 5 μg/cm(2) of test compounds at ALI using a state-of-the-art exposure system (Vitrocell™Cloud System). Endpoints related to the oxidative stress induction, anti-oxidant defence mechanisms, pro-inflammatory responses and cellular death were selected to evaluate the biocompatibility of silver particles and nanowires (AgNMs) and to further ascribe particular biological effects to the different morphologic properties between the three types of AgNMs evaluated. …”
Publicado 2019
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76460por Ibeneme, Sam Chidi, Irem, Franklin Onyedinma, Iloanusi, Nneka Ifeyinwa, Ezuma, Amarachi Destiny, Ezenwankwo, Fortune Elochukwu, Okere, Philip Chinedu, Nnamani, Amaka Obiageli, Ezeofor, Salome Nwaelom, Dim, Ngozi Regina, Fortwengel, Gerhard“…BACKGROUND: Compromised immune function, associated with human immune deficiency virus(HIV) infection, is improved by antiretroviral therapy(ART) which also decreases bone mineral density(BMD), and possibly the quality of life(QoL). …”
Publicado 2019
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