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  1. 76981
    “…Finally, we suggested our proposed KGs-guided computationally more effective candidate drug molecules compared to other published drugs by cross-validation with the state-of-the-art alternatives of top-ranked independent receptor proteins. …”
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    Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents
  2. 76982
    “…Although the clinical presentation may point towards a specific genetic cause, a combination of careful clinical assessment and state-of-the-art genetic testing is required. Objective: To describe 4 cases of PitNETs with heterogeneous clinical presentations and genetic causes from a cohort of Mexican patients with neuroendocrine tumors. …”
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    SAT603 A Heterogeneous Genetic Background Underlies Familial And Young-onset Pituitary Tumors
  3. 76983
    “…Best results were obtained with the combination of clinical baseline information and state-of-the-art image-based staging variables, highlighting the importance of good quality staging according to current guidelines and staging templates. …”
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    Development and multicenter validation of a multiparametric imaging model to predict treatment response in rectal cancer
  4. 76984
    “…Each reactive sample needed to be confirmed using state-of-the-art confirmation procedures on a blood sample. Close follow-up of participants who did not pick up their results, and those with reactive results, was included in the protocol. …”
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    Swab2know: An HIV-Testing Strategy Using Oral Fluid Samples and Online Communication of Test Results for Men Who Have Sex With Men in Belgium
  5. 76985
    “…METHODS: HIV-infected adults enrolled in the TREAT Asia HIV Observational Database were eligible if they had an HIV RNA measurement documented at the time of ART initiation. The dataset was randomly split into a derivation data set (75% of patients) and a validation data set (25%). …”
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    Factors associated with pre-treatment HIV RNA: application for the use of abacavir and rilpivirine as the first-line regimen for HIV-infected patients in resource-limited settings
  6. 76986
    “…Clinical trials take advantage of innovative strategies, clinical designs, and state-of-the-art technologies to evaluate efficacy and safety, however, early awareness of AE occurrences by investigators still needs to be systematically improved. …”
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    Expedited Safety Reporting Through an Alert System for Clinical Trial Management at an Academic Medical Center: Retrospective Design Study
  7. 76987
    “…Analogical reasoning with embeddings from deep learning (embedding analogies) may extract such biomedical facts, although the state-of-the-art focuses on pair-based proportional (pairwise) analogies such as man:woman::king:queen (“queen = −man +king +woman”). …”
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    Semantic Deep Learning: Prior Knowledge and a Type of Four-Term Embedding Analogy to Acquire Treatments for Well-Known Diseases
  8. 76988
    “…Yet, in treatment-experienced (TE) HIV patients, ART durability is essential for preventing further resistance and decreasing HIV-associated morbidity and mortality. …”
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    1027. Long-Term Efficacy, Safety, and Durability of Ibalizumab-Based Regimens in Subgroup of TMB-202 Participants
  9. 76989
    “…BACKGROUND: CAB+RPV LA administered monthly for HIV treatment is non-inferior to daily oral ART at maintaining HIV suppression but concerns about implementation of this novel treatment paradigm remain. …”
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    1037. Qualitative Findings from a Hybrid III Implementation-Effectiveness Study to Explore Perspectives of Health-care Staff on Early Implementation of Cabotegravir and Rilpivirine Long Acting (CAB+RPV LA) Injectable HIV treatment in the US (CUSTOMIZE)
  10. 76990
    “…Comparison of the proposed framework with state-of-the-art methods reveal that the proposed framework outperforms others in terms of accuracy and sensitivity. …”
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    Using handpicked features in conjunction with ResNet-50 for improved detection of COVID-19 from chest X-ray images
  11. 76991
    “…China has the oldest wild and planted tea trees in the world, fossil of a tea leaf from 35,400,000 years ago, and abundant tea-related literatures and art works. Moreover, tea may be the first Chinese herbal medicine (CHM) used by Chinese people in ancient times. …”
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    Tea and tea drinking: China’s outstanding contributions to the mankind
  12. 76992
    “…The current state of the art of commercial adsorption cooling systems rely on adsorbers based on coated finned heat exchangers to optimize the cooling power. …”
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    New preparation methods for coated heat exchangers in adsorption refrigeration and heat pumps applications
  13. 76993
    “…The VBC algorithm is based on a state-of-the-art convolutional neural network (CNN). The hypothesis is that VBC yields better accuracy than other consumer-grade fat measurements devices. 134 healthy adults ranging in age (21–76 years), sex (61.2% women), race (60.4% White; 23.9% Black), and body mass index (BMI, 18.5–51.6 kg/m(2)) were evaluated at two clinical sites (N = 64 at MGH, N = 70 at PBRC). …”
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    Smartphone camera based assessment of adiposity: a validation study
  14. 76994
    “…CONCLUSION: Using state-of-the-art techniques in lower respiratory tract samples obtained from a large representative patient cohort, we provide arguments for a three-level breach in antifungal immunity in IAPA and CAPA. …”
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    S3.3d Influenza versus COVID-19-associated pulmonary aspergillosis: Profiling lower respiratory tract epithelial and myeloid innate immunity in patient samples
  15. 76995
    “…With the support of the Choctaw Nation of Oklahoma (CNO), we address this oversight by using EHR data generated by this large, state-of-the-art tribal health care system to investigate C-MCIs. …”
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    Medication Adherence and Cardiometabolic Control Indicators Among American Indian Adults Receiving Tribal Health Services: Protocol for a Longitudinal Electronic Health Records Study
  16. 76996
    “…SOURCES OF EVIDENCE: The initial overall search was conducted in MEDLINE, Embase via Ovid, CINAHL, Web of Science, Social Sciences Citation Index, Arts & Humanities Citation Index, and the Cochrane Methodology Register from inception to June 2015. …”
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    Meta-research evaluating redundancy and use of systematic reviews when planning new studies in health research: a scoping review
  17. 76997
    “…To the best of our knowledge, the observed results for nine-class classification are significantly superior to the state-of-the-art approaches employed for COVID-19 detection. …”
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    PulDi-COVID: Chronic obstructive pulmonary (lung) diseases with COVID-19 classification using ensemble deep convolutional neural network from chest X-ray images to minimize severity and mortality rates
  18. 76998
    “…A unique product identification approach is presented, allowing a postoperative read-out with state-of-the-art hospital technology while enabling future access scenarios for patient and implant data. …”
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    Unique Device Identification–Based Linkage of Hierarchically Accessible Data Domains in Prospective Surgical Hospital Data Ecosystems: User-Centered Design Approach
  19. 76999
    por Regis, Federico
    Publicado 2009
    “…The LHC can be considered as the state of the art for superconducting magnets using the Nb-Ti superconductor technology. …”
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    Design of Nb$_{3}$Sn magnetic devices to study the superconductor degradation under variable mechanical load
  20. 77000
    por França Santos, Hugo Miguel
    Publicado 2013
    “…This constraint is not accomplished with the state-of-the-art front-end electronics because of its unsuited relatively large mass and of its associated water cooling system. …”
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    Highly Integrated Mixed-Mode Electronics for the readout of Time Projection Chambers
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