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  1. 2201
    “…Twenty-nine participants (16 with a history of childhood trauma and 13 without) underwent the cortisol awakening response (CAR) test. Saliva cortisol concentrations were determined by an enzyme immunoassay method, using a commercially available ELISA kit. …”
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    Clinical and neuroendocrine correlates of childhood maltreatment history in adults with bipolar disorder
  2. 2202
    por Kim, Nahyun, Ka, Soonjo, Park, Jonghoon
    Publicado 2023
    “…Longterm morning exercise tended to decrease cortisol concentrations after awakening and improve sleep quality. Future studies should examine the effects of long-term exercise timing and intensity on circadian rhythm and sleep.…”
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    Effects of exercise timing and intensity on physiological circadian rhythm and sleep quality: a systematic review
  3. 2203
    por Anderson, George
    Publicado 2023
    “…Another independently investigated aspect of the circadian rhythm is the cortisol awakening response (CAR), which is linked to stress-associated hypothalamus-pituitary-adrenal (HPA) axis activation. …”
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    Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses
  4. 2204
    “…We hypothesized that the application of glucose, insulin, thyroid and potassium would awaken inert tumor infiltrating lymphocytes to destroy the tumor. …”
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    The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity
  5. 2205
    “…INTERVENTIONS: During one experimental cycle, bright light was administered at home for 1 wk with a light box emitting white light at 4,300 lux at 41 cm for 45 min shortly after awakening. During the other experimental cycle, dim light was <100 lux at 41 cm with a one-tube fluorescent source. …”
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    Stimulatory Effect of Morning Bright Light on Reproductive Hormones and Ovulation: Results of a Controlled Crossover Trial
  6. 2206
    “…In terms of cortisol secretion, the AA genotype was related to a significantly higher awakening cortisol response (ACR) compared to the AG and GG group and the GG genotype group displayed a greater increase in cortisol secretion following a psychosocial stressor compared to the two other groups. …”
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    Polymorphism of the 5-HT(2A) Receptor Gene: Association with Stress-Related Indices in Healthy Middle-Aged Adults
  7. 2207
    “…A group that did not have difficulty with awakening was included as a control. RESULTS: The median time after sedation was discontinued until a head CT was performed was 2 days (interquartile range 1.375–2 days). …”
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    Head CT is of limited diagnostic value in critically ill patients who remain unresponsive after discontinuation of sedation
  8. 2208
    “…Secondary endpoints include (ii(i)) cortisol awakening response; and (ii(ii)) ventricular arrhythmias. …”
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    Rationale and design of WEBCARE: A randomized, controlled, web-based behavioral intervention trial in cardioverter-defibrillator patients to reduce anxiety and device concerns and enhance quality of life
  9. 2209
    “…Asthma was categorized as uncontrolled when the caregiver reported pre-specified criteria for daytime symptoms, nighttime awakening, activity limitation, or rescue medication based on the NAEPP guidelines. …”
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    Uncontrolled asthma: assessing quality of life and productivity of children and their caregivers using a cross-sectional Internet-based survey
  10. 2210
    “…Average improvements were: average asthma severity 2.61 points (95% confidence interval CI: 1.90–3.32); cough 0.93 (95% CI: 0.60–1.25); dyspnea 0.92 (95% CI: 0.56–1.28); exertion-induced symptoms 0.95 (95% CI: 0.64–1.25); frequency of asthma attacks 0.78 (95% CI: 0.41–1.14); awakening from asthma 0.90 (95% CI: 0.58–1.21); AQLQ overall score 1.44 (95% CI: 0.97–1.92); and KINDL asthma module 14.74 (95% CI: 9.70–19.78). …”
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    Anthroposophic therapy for asthma: A two-year prospective cohort study in routine outpatient settings
  11. 2211
    “…Self-reported insomnia complaints (poor sleep quality, difficulty in initiating sleep, difficulty in maintening sleep, and early morning awakening), EDS and sleep medication use were evaluated at baseline. …”
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    Insomnia, Daytime Sleepiness and Cardio-Cerebrovascular Diseases in the Elderly: A 6-Year Prospective Study
  12. 2212
    “…Salivary cortisol concentrations were measured at 3, 6 and 9 h post awakening over two consecutive weekdays, together with measures of perceived stress. …”
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    Green Space and Stress: Evidence from Cortisol Measures in Deprived Urban Communities
  13. 2213
    por Bell, Brent C, Butler, E Brian
    Publicado 2013
    “…Some patients also reported pain awakening them randomly at night (eg, sleep interruption). …”
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    Management of predictable pain using fentanyl pectin nasal spray in patients undergoing radiotherapy
  14. 2214
    “…Subsequently, the rats were video monitored for 72 h to detect the occurrence of behavioral seizures upon awakening. The average number and duration of seizures on EEG and the number of behavioral seizures were measured. …”
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    Seizure Control of Current Shunt on Rats with Temporal Lobe Epilepsy and Neocortical Epilepsy
  15. 2215
    “…Propofol may cause delayed awakening after prolonged infusion. Propanidid and AZD3043 have a different metabolic pathway compared to propofol, resulting in a short-acting clinical profile. …”
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    Synthesis and Evaluation of Fluorine-Substituted Phenyl Acetate Derivatives as Ultra-Short Recovery Sedative/Hypnotic Agents
  16. 2216
    “…The effects of study drugs on morning BP surges, including sleep trough surge (early morning SBP minus the lowest night-time SBP) and prewaking surge (early morning SBP minus SBP before awakening), were evaluated. Patients with sleep trough surge of at least 35 mmHg were defined by the presence of a morning BP surge (the ‘surge group’). …”
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    Effect of azilsartan versus candesartan on morning blood pressure surges in Japanese patients with essential hypertension
  17. 2217
    “…More important, patients reported marked improvements in headache impact (P < 0.01), neck-disability scores (P < 0.01), awakening due to headache (P < 0.01), and sleep problems (9-item; P < 0.05) on the MOS-SS. …”
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    Whiplash Patients with Cervicogenic Headache After Lateral Atlanto-Axial Joint Pulsed Radiofrequency Treatment
  18. 2218
    “…The nocturnal IOP was measured in the supine position, right LDP, and left LDP, with randomized sequences, under dim light (<10 lux) at 11:30 pm, 1:30 am, 3:30 am, and 5:30 am. The subjects were awakened and maintained each position for 5 min before the measurement. …”
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    The Effect of Lateral Decubitus Position on Nocturnal Intraocular Pressure over a Habitual 24-Hour Period in Healthy Adults
  19. 2219
    “…Two morning assessments (since awakening and since the last assessment) and one evening assessment were made each day. …”
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    Symptoms and impact of COPD assessed by an electronic diary in patients with moderate-to-severe COPD: psychometric results from the SHINE study
  20. 2220
    “…But time of regular breathing, awakening, extubation, and emergence were significantly delayed in group D than C. …”
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    Emergence agitation prevention in paediatric ambulatory surgery: A comparison between intranasal Dexmedetomidine and Clonidine
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