“…Neurons are specialized cells with a complex architecture that includes elaborate dendritic branches and a long, narrow axon that extends from the cell body to the synaptic terminal. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The mechanisms by which axonal degeneration occurs, even in the presence of apparently normal myelin sheaths, remain unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The odorant receptor is expressed at the cilia, where it binds odorants, and at the axon terminal. The mechanism of activation and function of the odorant receptor at the axon terminal is, however, still unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the adult nervous system axon caliber varies widely amongst different tracts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We consider the effect of non-cylindrical axonal shape on axonal diameter mapping with diffusion MRI. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Axonopathies are caused by brain trauma and genetic diseases that perturb or disrupt the axon MT infrastructure and, with it, the dynamic interplay of motor proteins and cargo essential for axonal maintenance and neuronal signaling. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Axons functionally link the somato-dendritic compartment to synaptic terminals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Building precise neural circuits necessitates the elimination of axonal projections that have inaccurately formed during development. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nerve extracts containing tubulin labeled by axonal transport were analyzed by electrophoresis and differential extraction. …”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The emerging association between sterile alpha and TIR motif-containing 1 (SARM1), a protein so far mostly associated with axon degeneration, and sporadic ALS is another major theme. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Insufficient RAG expression in the injured neuron and the presence of inhibitory ECM at the lesion, leads to structural alterations in the axon that perturb the growth machinery, or form an extraneous barrier to axonal regeneration, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The axonal transport of the diverse isotubulins in the motor axons of the rat sciatic nerve was studied by two-dimensional polyacrylamide gel electrophoresis after intraspinal injection of [35S]methionine. 3 wk after injection, the nerve segments carrying the labeled axonal proteins of the slow components a (SCa) and b (SCb) of axonal transport were homogenized in a cytoskeleton-stabilizing buffer and two distinct fractions, cytoskeletal (pellet, insoluble) and soluble (supernatant), were obtained by centrifugation. …”
Enlace del recurso
Enlace del recurso

“…We found that neonatal axons grew 40% faster than adult axons (11.5 µm/hour vs. 8.2 µm/hour). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTERPRETATION: Our study shows that peripheral sensory axons are more vulnerable for ischemia than motor axons, with faster inexcitability during ischemia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PURPOSE: Human intraretinal myelination of ganglion cell axons occurs in about 1% of the population. We examined myelin thickness and axon diameter in human retinal specimens containing myelinated retinal ganglion cell axons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso