3′RNA Sequencing Accurately Classifies Formalin-Fixed Paraffin-Embedded Uterine Leiomyomas

por Mehine, Miika, Khamaiseh, Sara, Ahvenainen, Terhi, Heikkinen, Tuomas, Äyräväinen, Anna, Pakarinen, Päivi, Härkki, Päivi, Pasanen, Annukka, Bützow, Ralf, Vahteristo, Pia
Publicado 2020

3′RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1

por Jokinen, Vilja, Mehine, Miika, Reinikka, Siiri, Khamaiseh, Sara, Ahvenainen, Terhi, Äyräväinen, Anna, Härkki, Päivi, Bützow, Ralf, Pasanen, Annukka, Vahteristo, Pia
Publicado 2022

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

por Niskakoski, Anni, Kaur, Sippy, Staff, Synnöve, Renkonen-Sinisalo, Laura, Lassus, Heini, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Bützow, Ralf, Peltomäki, Päivi
Publicado 2015

MiR-34a Expression Has an Effect for Lower Risk of Metastasis and Associates with Expression Patterns Predicting Clinical Outcome in Breast Cancer

por Peurala, Hanna, Greco, Dario, Heikkinen, Tuomas, Kaur, Sippy, Bartkova, Jirina, Jamshidi, Maral, Aittomäki, Kristiina, Heikkilä, Päivi, Bartek, Jiri, Blomqvist, Carl, Bützow, Ralf, Nevanlinna, Heli
Publicado 2011

Low Expression of Stanniocalcin 1 (STC-1) Protein Is Associated With Poor Clinicopathologic Features of Endometrial Cancer

por Khatun, Masuma, Urpilainen, Elina, Ahtikoski, Anne, Arffman, Riikka K., Pasanen, Annukka, Puistola, Ulla, Tapanainen, Juha S., Andersson, Leif C., Butzow, Ralf, Loukovaara, Mikko, Piltonen, Terhi T.
Publicado 2021

Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy

por Björk, Johanna K., Ahonen, Ilmari, Mirtti, Tuomas, Erickson, Andrew, Rannikko, Antti, Bützow, Anna, Nordling, Stig, Lundin, Johan, Lundin, Mikael, Sistonen, Lea, Nees, Matthias, Åkerfelt, Malin
Publicado 2018

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

por Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
Publicado 2017

Global metabolomic profiling of uterine leiomyomas

por Heinonen, Hanna-Riikka, Mehine, Miika, Mäkinen, Netta, Pasanen, Annukka, Pitkänen, Esa, Karhu, Auli, Sarvilinna, Nanna S, Sjöberg, Jari, Heikinheimo, Oskari, Bützow, Ralf, Aaltonen, Lauri A, Kaasinen, Eevi
Publicado 2017

Recurrent moderate‐risk mutations in Finnish breast and ovarian cancer patients

por Nurmi, Anna, Muranen, Taru A., Pelttari, Liisa M., Kiiski, Johanna I., Heikkinen, Tuomas, Lehto, Sini, Kallioniemi, Anne, Schleutker, Johanna, Bützow, Ralf, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli
Publicado 2019

A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase

por Mehine, Miika, Ahvenainen, Terhi, Khamaiseh, Sara, Härkönen, Jouni, Reinikka, Siiri, Heikkinen, Tuomas, Äyräväinen, Anna, Pakarinen, Päivi, Härkki, Päivi, Pasanen, Annukka, Levonen, Anna-Liisa, Bützow, Ralf, Vahteristo, Pia
Publicado 2022

Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas

por Välimäki, Niko, Jokinen, Vilja, Cajuso, Tatiana, Kuisma, Heli, Taira, Aurora, Dagnaud, Olivia, Ilves, Sini, Kaukomaa, Jaana, Pasanen, Annukka, Palin, Kimmo, Heikinheimo, Oskari, Bützow, Ralf, Aaltonen, Lauri A., Karhu, Auli
Publicado 2023

Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

por Santos, João Manuel, Heiniö, Camilla, Cervera-Carrascon, Victor, Quixabeira, Dafne C A, Siurala, Mikko, Havunen, Riikka, Butzow, Ralf, Zafar, Sadia, de Gruijl, Tanja, Lassus, Heini, Kanerva, Anna, Hemminki, Akseli
Publicado 2020

Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness

por Karvonen, Hanna, Arjama, Mariliina, Kaleva, Laura, Niininen, Wilhelmiina, Barker, Harlan, Koivisto-Korander, Riitta, Tapper, Johanna, Pakarinen, Päivi, Lassus, Heini, Loukovaara, Mikko, Bützow, Ralf, Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2020

Transcriptional Regulation of PIK3CA Oncogene by NF-κB in Ovarian Cancer Microenvironment

por Yang, Nuo, Huang, Jia, Greshock, Joel, Liang, Shun, Barchetti, Andrea, Hasegawa, Kosei, Kim, Sarah, Giannakakis, Antonis, Li, Chunsheng, O'Brien-Jenkins, Anne, Katsaros, Dionyssios, Bützow, Ralf, Coukos, George, Zhang, Lin
Publicado 2008

Altered glycosylation of glycodelin in endometrial carcinoma

por Hautala, Laura C., Pang, Poh-Choo, Antonopoulos, Aristotelis, Pasanen, Annukka, Lee, Cheuk-Lun, Chiu, Philip C. N., Yeung, William S. B., Loukovaara, Mikko, Bützow, Ralf, Haslam, Stuart M., Dell, Anne, Koistinen, Hannu
Publicado 2020

Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate

por Kolterud, Åsa, Välimäki, Niko, Kuisma, Heli, Patomo, Joonatan, Ilves, Sini T, Mäkinen, Netta, Kaukomaa, Jaana, Palin, Kimmo, Kaasinen, Eevi, Karhu, Auli, Pasanen, Annukka, Bützow, Ralf, Heikinheimo, Oskari, Kopp Kallner, Helena, Aaltonen, Lauri A
Publicado 2022

Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis

por Nousiainen, Susanna, Kuismin, Outi, Reinikka, Siiri, Manninen, Roosa, Khamaiseh, Sara, Kuivalainen, Mari, Terho, Anna, Koivurova, Sari, Niinimäki, Maarit, Salokas, Kari, Varjosalo, Markku, Ahtikoski, Anne, Bützow, Ralf, Lindgren, Outi, Uimari, Outi, Vahteristo, Pia
Publicado 2023

A missense mutation in the BRCA2 gene in three siblings with ovarian cancer.

por Roth, S., Kristo, P., Auranen, A., Shayehgi, M., Seal, S., Collins, N., Barfoot, R., Rahman, N., Klemi, P. J., Grénman, S., Sarantaus, L., Nevanlinna, H., Butzow, R., Ashworth, A., Stratton, M. R., Aaltonen, L. A.
Publicado 1998

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas

por Kämpjärvi, Kati, Mäkinen, Netta, Mehine, Miika, Välipakka, Salla, Uimari, Outi, Pitkänen, Esa, Heinonen, Hanna-Riikka, Heikkinen, Tuomas, Tolvanen, Jaana, Ahtikoski, Anne, Frizzell, Norma, Sarvilinna, Nanna, Sjöberg, Jari, Bützow, Ralf, Aaltonen, Lauri A, Vahteristo, Pia
Publicado 2016

Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors

por Haltia, Ulla-Maija, Pihlajoki, Marjut, Andersson, Noora, Mäkinen, Lotta, Tapper, Johanna, Cervera, Alejandra, Horlings, Hugo M, Turpeinen, Ursula, Anttonen, Mikko, Bützow, Ralf, Unkila-Kallio, Leila, Carpén, Olli, Wilson, David B, Heikinheimo, Markku, Färkkilä, Anniina
Publicado 2020