“…Depletion of Cdkn1a and Bbc3, which were upregulated by Trp53, rescued Rb1-deficient cells from undergoing cell cycle arrest and apoptosis. …”
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“…This includes how FOXM1 impacts on different subtypes of breast cancer, that is, luminal/estrogen receptor positive (ER+), expressing human epidermal growth factor receptor 2 (HER2), basal-like breast cancer (BBC), and triple negative breast cancer (TNBC). …”
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“…The huge number of substrates and positive support of in vivo evidence indicate that the BBC method is a powerful tool for protease substrates identification.…”
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“…It takes the outputs and decision-making of one of the world's most influential broadcasters, the BBC, as its primary focus. The paper considers these themes in terms of stories, touching on some of the broader societal frames of understanding into which they can be grouped. …”
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“…However, the sale of Parker’s skull – described as an ‘antique piece’ in the press coverage (BBC News 2014) – is a reminder that the global marketplace in objectified body parts is disturbing in quite a different manner.…”
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“…In light of this, a fermented milk, made by using Bifidobacterium breve C50 (BbC50) and Streptococcus thermophilus 065 (St065) with a prebiotic mixture—short chain galactooligosaccharides/long chain fructooligosaccharides (scGOS/lcFOS 9:1)—with potential to impact the intestinal microbiota composition was tested. …”
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“…We conducted five experiments—including one preregistered replication with a national sample and one field experiment on the BBC News website (total n = 5,780)—to examine whether communicating epistemic uncertainty about facts across different topics (e.g., global warming, immigration), formats (verbal vs. numeric), and magnitudes (high vs. low) influences public trust. …”
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“…Here, we examine the record choices of famous guests (n = 80; mean age = 61.6 years) interviewed for Desert Island Discs, a long-running popular radio programme on BBC Radio 4. Half of all choices were shown to have been most important between the ages of 10 and 30 years, and the most popular reason for their relevance was the song’s link to memories of a person, period, or place. …”
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“…We make these features publicly available for the UvA-NEMO and BBC databases, which will allow other researchers to further improve the classification scores, while preserving the interpretation capabilities attributed to the use of facial action units. …”
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“…Plastics are considered one of the most serious environmental global concerns as they are ubiquitous and contribute to the build-up of pollution. In August 2020, the BBC reported that scientists found 12–21 million tonnes of tiny plastic fragments floating in the Atlantic Ocean. …”
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“…Similarly, the biofilm bactericidal concentration (BBC) at 125 μg/ml and the minimum biofilm elimination concentration to remove 90% of the total biofilm mass (MBEC90) were measured at a concentration range of 15.625–1.95 μg/ml. …”
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“…Furthermore, several dysregulated genes are involved in biological processes that can lead to promote cancer including “Evading apoptosis” (BAD, BBC3, EGF, FGFR2, FLT3LG, HMOX1, HRAS, IFNAR2, IGF1R, IL12RB1, IL13RA1, IL15, IL2RB, IL2RG, IL6R, KEAP1, MGST1, PDGFA, PDGFRB, PIK3R3, RALB, RALGDS, RASSF1, SOS1, TGFA, TXNRD3), “Proliferation” (APC, BRAF, CCND2, CCND3, CCNE2, FGFR2, FLT3LG, FZD1, FZD6, HMOX1, HRAS, IGF1R, KEAP1, LRP6, MAPK3, MGST1, PDGFA, PDGFB, PDGFRB, RB1, SOS1, TGFA, TXNRD3, WNT10B), “Sustained angiogenesis” (BRAF, FGFR2, FLT3LG, HRAS, IGF1R, JAG1, MAPK3, NOTCH2, PDGFA, PDGFB, PDGFRB, SOS1, TGFA, TGFB1), “Genomic instability” (BAD, BBC3) and “Insensitivity to anti-growth signals” (SMAD2, TGFB1). …”
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