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421“…PRINCIPAL FINDINGS: Only 113 articles in a 53-month time period met the inclusion criteria, with no strong trends or increases in coverage. Overall, the BBC had the highest coverage with 20 results, followed by the Financial Times and Agence France Presse. …”
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422“…RAD50 (RAD50 homolog), PLK3 (polo-like kinase 3), GADD45A (growth arrest and DNA damage-inducible, alpha), DDB2 (damage-specific DNA-binding protein 2), BBC3 (BCL2-binding component 3) and IER5 (immediate early response 5) gene expression levels were found to undergo significant oscillating changes over a broad dose range of 2–8 Gy at post-exposure time points observed. …”
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423“…METHODS AND FINDINGS: Participants were 32,827 (age 18–85 years) self-selected respondents from the general population who completed an open-access online battery of questionnaires hosted by the BBC. An initial confirmatory factor analysis was performed to assess the adequacy of the proposed factor structure and the relationships between latent and measured variables. …”
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424“…TRECVID INS, MIRFLICKR-1M), and we further demonstrate the performance and real-world applicability of our methods over a dataset sourced from 10,000 h of unedited footage from BBC News, comprising 5M+ key frames.…”
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425“…We measured the maternal blood PBDE levels and cord blood TNFα promoter methylation levels on 46 paired samples of maternal and cord blood from the Boston Birth Cohort (BBC). We showed that decreased cord blood TNFα methylation associated with high maternal PBDE47 exposure. …”
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426por Lu, Tao, Zhang, Ye, Kidane, Yared, Feiveson, Alan, Stodieck, Louis, Karouia, Fathi, Ramesh, Govindarajan, Rohde, Larry, Wu, Honglu“…The microarray data was confirmed with a PCR array analysis containing a set of genes involved in DNA damage signaling; with BBC3, CDKN1A, PCNA and PPM1D being significantly upregulated in both flight and ground cells after bleomycin treatment. …”
Publicado 2017
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427“…In this research project, we present the development and validation of the data produced by an up-to-date, scientist-friendly program for identifying jargon in popular written texts, based on a corpus of over 90 million words published in the BBC site during the years 2012–2015. The validation of results by the jargon identifier, the De-jargonizer, involved three mini studies: (1) comparison and correlation with existing frequency word lists in the literature; (2) a comparison with previous research on spoken language jargon use in TED transcripts of non-science lectures, TED transcripts of science lectures and transcripts of academic science lectures; and (3) a test of 5,000 pairs of published research abstracts and lay reader summaries describing the same article from the journals PLOS Computational Biology and PLOS Genetics. …”
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428Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancerpor Tedaldi, Gianluca, Tebaldi, Michela, Zampiga, Valentina, Danesi, Rita, Arcangeli, Valentina, Ravegnani, Mila, Cangini, Ilaria, Pirini, Francesca, Petracci, Elisabetta, Rocca, Andrea, Falcini, Fabio, Amadori, Dino, Calistri, Daniele“…These patients had a much higher percentage of bilateral breast cancer (BBC) and a lower rate of OC than BRCA-mutated patients and patients with no pathogenic mutations: as a consequence, the surveillance protocol should be customized to the patient genetic characteristics.…”
Publicado 2017
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429por Kovács, Anikó, Persson, Fredrik, Persson, Marta, Andersson, Mattias K., Stenman, Göran“…In the present study, we describe a unique case of synchronous BBC in a 59-year-old previously healthy woman with no known family history of breast or ovarian cancer. …”
Publicado 2017
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430por Yoon, Soonsang, Beermann, Mary Lou, Yu, Bryant, Shao, Di, Bachschmid, Markus, Miller, Jeffrey Boone“…RESULTS: In cultures of myogenic cells from MDC1A donors, p53 accumulated in a subset of nuclei and aberrant caspase activation was inhibited by the p53 inhibitor pifithrin-alpha. Also, the p53 target BBC3 (PUMA) was upregulated in both MDC1A myogenic cells and Lama2–/– mouse muscles. …”
Publicado 2018
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431por Alotaibi, Moureq R, Hassan, Zeinab K, Al-Rejaie, Salim S, Alshammari, Musaad A, Almutairi, Mashal M, Alhoshani, Ali R, Alanazi, Wael A, Hafez, Mohamed M, Al-Shabanah, Othman A“…IL-10 gene silencing causes down regulation of both PI3K/AKT and Bcl2 gene expression and also increases the Bbc3, BAX caspase3, and caspase 3 cleavage expression levels. …”
Publicado 2018
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432por Synnott, Naoise C., Madden, Stephen F., Bykov, Vladimir J.N., Crown, John, Wiman, Klas G., Duffy, Michael J.“…We did not detect upregulation of canonical p53 target genes such as CDKN1A (p21), 14-3-3σ, BBC3 (PUMA), and PMAIP1 (NOXA) by RNA-seq, but these genes were induced according to analysis by qPCR. …”
Publicado 2018
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433“…FOXM1 expression was remarkably high in testicular germ cell tumors (TGCT), high-grade serous ovarian cancer (HGSC), and basal breast cancer (BBC). FOXM1 expression in cancer was associated with genomic instability, as measured using aneuploidy signatures. …”
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434por Dusaulcy, Rodolphe, Handgraaf, Sandra, Visentin, Florian, Vesin, Christian, Philippe, Jacques, Gosmain, Yvan“…These effects are associated with the regulation of a series of genes, including proliferation and stress markers Mki67 and Bbc3 in mouse and human alpha-cells, potentially involved in miR-132-3p functions. …”
Publicado 2019
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435“…METHOD: 223,537 UK respondents aged 16+ years were surveyed between 2009 and 2013 in the British Broadcasting Corporation (BBC) Lab UK Study. Respondents provided information on bodily pain, smoking status and a range of sociodemographic, health, behavioural and psychological characteristics. …”
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436“…Using 940 comments from the BBC “Have Your Say” messageboard, this study adopts sentiment analysis to understand consumers’ opinions about the introduction and implementation of DRS in Scotland. …”
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437por Lopes, Beatriz C., Braga, Cristine Z., Ventura, Fabrício V., de Oliveira, Jéssica G., Kato-Junior, Edson M., Bordin-Junior, Newton A., Zuccari, Debora A. P. C.“…Methods: RT-qPCR was performed and MiRNA expression analysis was obtained from plasma and fragments of BC and benign breast condition (BBC) women patients, plus healthy subjects. Additionally, the immunohistochemistry technique was carried out to analyze the expression of target proteins. …”
Publicado 2021
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438“…The primary information sources used by our participants were BBC News, group messaging such as WhatsApp, and NHS England. …”
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439por Xu, Shi, Murrell, George, Golding, Sarah E., Brockett, Beth F. T., Gatersleben, Birgitta, Scarles, Caroline, White, Emma V., Willis, Cheryl, Wyles, Kayleigh J.“…Data consisted of comments on videos containing highlights from the British Broadcasting Corporation’s (BBC) Springwatch 2020 television series, and from a UK television presenter and naturalist’s (Chris Packham) livestream videos, posted on Facebook from March to July, 2020. …”
Publicado 2021
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440por Pearce, Ellie, Barreto, Manuela, Victor, Christina, Hammond, Claudia, Eccles, Alice M., Richins, Matthew T., O’Neil, Alisha, Knowles, Megan L., Qualter, Pamela“…Using data from the British Broadcasting Corporation (BBC) Loneliness Experiment that included participants aged 16–99 years (N = 54,060), we (i) test for replication in a larger worldwide sample and (ii) extend those linear model analyses to other age groups. …”
Publicado 2020
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