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  1. 75861
    “…Furthermore, this cognitive reserve function of NREM SWA remained significant when accounting both for covariates, and factors previously linked to resilience, suggesting that sleep might be an independent cognitive reserve resource. Beyond such mechanistic insights are potential therapeutic implications. …”
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    NREM sleep as a novel protective cognitive reserve factor in the face of Alzheimer's disease pathology
  2. 75862
    por Tavares, Julia Valentim, Oliveira, Rafael S., Mencuccini, Maurizio, Signori-Müller, Caroline, Pereira, Luciano, Diniz, Francisco Carvalho, Gilpin, Martin, Marca Zevallos, Manuel J., Salas Yupayccana, Carlos A., Acosta, Martin, Pérez Mullisaca, Flor M., Barros, Fernanda de V., Bittencourt, Paulo, Jancoski, Halina, Scalon, Marina Corrêa, Marimon, Beatriz S., Oliveras Menor, Imma, Marimon, Ben Hur, Fancourt, Max, Chambers-Ostler, Alexander, Esquivel-Muelbert, Adriane, Rowland, Lucy, Meir, Patrick, Lola da Costa, Antonio Carlos, Nina, Alex, Sanchez, Jesus M. B., Tintaya, Jose S., Chino, Rudi S. C., Baca, Jean, Fernandes, Leticia, Cumapa, Edwin R. M., Santos, João Antônio R., Teixeira, Renata, Tello, Ligia, Ugarteche, Maira T. M., Cuellar, Gina A., Martinez, Franklin, Araujo-Murakami, Alejandro, Almeida, Everton, da Cruz, Wesley Jonatar Alves, del Aguila Pasquel, Jhon, Aragāo, Luís, Baker, Timothy R., de Camargo, Plinio Barbosa, Brienen, Roel, Castro, Wendeson, Ribeiro, Sabina Cerruto, Coelho de Souza, Fernanda, Cosio, Eric G., Davila Cardozo, Nallaret, da Costa Silva, Richarlly, Disney, Mathias, Espejo, Javier Silva, Feldpausch, Ted R., Ferreira, Leandro, Giacomin, Leandro, Higuchi, Niro, Hirota, Marina, Honorio, Euridice, Huaraca Huasco, Walter, Lewis, Simon, Flores Llampazo, Gerardo, Malhi, Yadvinder, Monteagudo Mendoza, Abel, Morandi, Paulo, Chama Moscoso, Victor, Muscarella, Robert, Penha, Deliane, Rocha, Mayda Cecília, Rodrigues, Gleicy, Ruschel, Ademir R., Salinas, Norma, Schlickmann, Monique, Silveira, Marcos, Talbot, Joey, Vásquez, Rodolfo, Vedovato, Laura, Vieira, Simone Aparecida, Phillips, Oliver L., Gloor, Emanuel, Galbraith, David R.
    Publicado 2023
    “…Moreover, in regions of more pronounced climatic change, we find evidence that forests are losing biomass, suggesting that species in these regions may be operating beyond their hydraulic limits. Continued climate change is likely to further reduce HSM(50) in the Amazon(6,7), with strong implications for the Amazon carbon sink.…”
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    Basin-wide variation in tree hydraulic safety margins predicts the carbon balance of Amazon forests
  3. 75863
    “…We developed and conducted a pilot study of the ConnectMyVariant intervention, in which participants received support to contact at-risk relatives that extended beyond first-degree relatives and encourage relatives to obtain genetic testing and connect with others having the same variant through email and social media. …”
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    Extended Family Outreach in Hereditary Cancer Using Web-Based Genealogy, Direct-to-Consumer Ancestry Genetics, and Social Media: Mixed Methods Process Evaluation of the ConnectMyVariant Intervention
  4. 75864
    “…Notably, the changes in knowledge, beliefs, and strategy use continued beyond the initial program. This is particularly important for supporting the growing number of older adults living with cognitive concerns. …”
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    Examination of the Feasibility, Acceptability, and Efficacy of the Online Personalised Training in Memory Strategies for Everyday Program for Older Adults: Single-Arm Pre-Post Trial
  5. 75865
    “…Blood pressure (BP) control is a global health issue with an increase in BP beyond the normal BP leading to different stages of hypertension in humans and hence the need to identify risk factors of BP for efficient and effective control. …”
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    Mixed effects logistic regression analysis of blood pressure among Ghanaians and associated risk factors
  6. 75866
    “…CONCLUSION: During AT, systematic identification of EGM regions of high frequency within low voltage can significantly improve discrimination of the site of AT. termination, beyond. [Figure: see text]…”
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    Systematic identification of low voltage-high frequency electrogram zones at sites of left atrial reentrant tachycardia termination
  7. 75867
    “…Patients that underwent ablation beyond PVI (except for cavo-tricuspid isthmus ablation) were excluded. …”
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    Pulsed field versus cryoballoon ablation of atrial fibrillation: A comparison of efficacy and safety in a 400 patient cohort
  8. 75868
    “…Given the accessibility to treatment issues, more evaluation is needed to assess the potential benefits of fully automated self-help transdiagnostic digital interventions. Innovating beyond the current transdiagnostic one-size-fits-all shared mechanistic approach may also lead to further improvements. …”
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    A Fully Automated Self-help Biopsychosocial Transdiagnostic Digital Intervention to Reduce Anxiety and/or Depression and Improve Emotional Regulation and Well-being: Pre–Follow-up Single-Arm Feasibility Trial
  9. 75869
    “…By day 8, median C5a levels were reduced by 87% in the vilobelimab group (median 14.5 ng/mL [IQR 9.5–21.0 ng/mL], p < 0.001) versus an 11% increase in the placebo group (median 119.2 ng/mL [IQR 85.9–152.1 ng/mL]). Beyond day 8, though plasma sampling was sparse, C5a levels did not reach screening levels in the vilobelimab group while C5a levels remained elevated in the placebo group. …”
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    Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill,  invasively mechanically ventilated COVID-19 patients
  10. 75870
    “…The authors propose that additional information relating to the types of procedures and the level of supervision or autonomy would enable a more comprehensive comparison of SOPs, going beyond the granularity offered by the WHO framework. …”
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    Understanding the scope of practice of physician associate/physician associate comparable professions using the World Health Organization global competency and outcomes framework for universal health coverage
  11. 75871
    “…Of 158 patients who had progressed beyond 1L therapy, the mean (SD) time-to-treatment discontinuation was 5.1 (4.3) months; 75.9% of whom completed their 1L treatment as intended. …”
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    Treatment patterns and outcomes of patients with metastatic non-small cell lung cancer in five European countries: a real-world evidence survey
  12. 75872
    “…INTRODUCTION: The potential additive benefits of rehabilitation beyond spontaneous recovery post-COVID-19 currently remain unknown. …”
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    Additive benefit of rehabilitation on physical status, symptoms and mental health after hospitalisation for severe COVID-19 pneumonia
  13. 75873
    “…GFI uses readily available CMR data without additional post-processing and may provide additional prognostic value in pediatric PH patients beyond traditional CMR markers. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12968-023-00947-8.…”
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    Ventricular global function index is associated with clinical outcomes in pediatric pulmonary hypertension
  14. 75874
    “…BACKGROUND: Sepsis-associated acute kidney injury (SA-AKI) is associated with high morbidity, with no current therapies available beyond continuous renal replacement therapy (CRRT). …”
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    Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock
  15. 75875
    “…The high-volume disease was defined as the presence of visceral metastases and/or ≥ 4 bone metastases (≥ 1 beyond the vertebral bodies or the pelvis) based on the findings of (18)F-PSMA-1007 PET/CT and/or CI. …”
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    Impact of non-regional lymph node metastases accurately revealed on (18)F-PSMA-1007 PET/CT in the clinical management of metastatic hormone-sensitive prostate cancer
  16. 75876
    “…A completely online format has many benefits that extend beyond the pandemic, such as easier access to participants (including those off-service or at remote sites), no requirement for a physical space, and easier recording of sessions. …”
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    A Novel Virtual Emergency Medicine Residents-as-Teachers (RAT) Curriculum
  17. 75877
    “…The spatial co-localization of the infiltrating MES GBM and myeloid cells within the 5ALA + region indicates PpIX fluorescence can effectively be utilized to resect the immune reactive zone beyond the tumor core. Finally, 5ALA + gene signatures were associated with poor survival and recurrence in GBM, signifying that the transition from primary to recurrent GBM is not discrete but rather a continuum whereby primary infiltrative 5ALA + remnant tumor cells more closely resemble the eventual recurrent GBM. …”
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    Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence
  18. 75878
    “…BACKGROUND: The management of antidiabetic therapy in people with type 2 diabetes (T2D) has evolved beyond glycemic control. In this context, Brazil and Portugal defined a joint panel of four leading diabetes societies to update the guideline published in 2020. …”
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    2023 UPDATE: Luso-Brazilian evidence-based guideline for the management of antidiabetic therapy in type 2 diabetes
  19. 75879
    “…We extended the analysis beyond PTB by calculating risks over the whole distribution of gestational age, including “early term” (37 to 38 weeks). …”
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    Paternal and maternal psychiatric history and risk of preterm and early term birth: A nationwide study using Swedish registers
  20. 75880
    “…Ultimately, the AM approach to smoking cessation could greatly improve public health in the developing world and beyond. TRIAL REGISTRATION: ClinicalTrials.gov NCT05746442; https://clinicaltrials.gov/ct2/show/NCT05746442 INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/48923…”
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    Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People With HIV (Project EndIT): Protocol for a Randomized Controlled Trial
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