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  1. 76041
    “…Serial intervals decreased over time (6.70 days in wave 1 versus 4.35 days in wave 2) and with tertiary transmission or beyond (percentage contribution: –50.75% to –17.31%), but were lengthened by mobility (percentage contribution: 0.83%). …”
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    Evolving Epidemiological Characteristics of COVID-19 in Hong Kong From January to August 2020: Retrospective Study
  2. 76042
    “…The primary outcome was conception leading to live birth within 12 months after randomization, defined as the birth of a living foetus beyond 24 weeks of gestational age. We analysed the data on an intention-to-treat basis and calculated relative risks with 95% CI. …”
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    Septum resection versus expectant management in women with a septate uterus: an international multicentre open-label randomized controlled trial
  3. 76043
    por Kasela, Silva, Ortega, Victor E., Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L., Barjaktarevic, Igor Z., Barr, R. Graham, Bleecker, Eugene R., Bowler, Russell P., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Curtis, Jeffrey L., Han, MeiLan K., Hansel, Nadia N., Hoffman, Eric A., Kaner, Robert J., Krishnan, Jerry A., Martinez, Fernando J., McDonald, Merry-Lynn N., Meyers, Deborah A., Paine, Robert, Peters, Stephen P., Castro, Mario, Denlinger, Loren C., Erzurum, Serpil C., Fahy, John V., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce D., Li, Xingnan, Moore, Wendy C., Wenzel, Sally E., Zein, Joe, Langelier, Charles, Woodruff, Prescott G., Lappalainen, Tuuli, Christenson, Stephanie A.
    Publicado 2021
    “…To identify airway biology beyond ACE2 binding that may contribute to increased susceptibility, we used gene set enrichment analyses to determine if gene expression changes indicative of a suppressed airway immune response observed early in SARS-CoV-2 infection are also observed in association with host factors. …”
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    Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium
  4. 76044
    “…The telemedicine platform is supported in many specialties, allowing students various options to continue their education without interruption during the COVID-19 pandemic, and beyond. Telemedicine platforms are projected to grow exponentially due to the COVID-19 pandemic, allowing a segue for medical schools to modify their curricula by incorporating telemedicine programs. …”
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    How the COVID-19 Pandemic Impacted Medical Education during the Last Year of Medical School: A Class Survey
  5. 76045
    “…Of the 22 patients in COVID-19 arm that underwent testing for anti-SARS-CoV-2 IgG antibodies beyond 7 months, all had detectable antibodies. A higher proportion of the patients with COVID-19 were frail compared to patients without a diagnosis of COVID-19 (64.3% vs 34.1%, p = 0.003). …”
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    Investigating the utility of COVID-19 antibody testing in end-stage renal disease patients receiving haemodialysis: a cohort study in the United Kingdom
  6. 76046
    “…Rehfeld JF. Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: cholecystokinin and gastrin peptides. …”
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    The Effect of Proton Pump Inhibitors on Insulin-Glucose Homeostasis in Patients With Type 2 Diabetes Mellitus
  7. 76047
    “…Results: All 59 subjects completed the initial 4-week period and continued in the OLE; 58 subjects continue in the OLE beyond 6 months (1 withdrew unrelated to safety or efficacy). …”
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    TransCon PTH as a Hormone Replacement Therapy for Patients with Hypoparathyroidism: 6-Month Update from the PaTH Forward Open-Label Extension
  8. 76048
    “…The 3 models had comparable calibration up to 2 years from entry. Beyond 2 years, the standard Cox regression overestimated the risk of kidney failure. …”
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    Accounting for the Competing Risk of Death to Predict Kidney Failure in Adults With Stage 4 Chronic Kidney Disease
  9. 76049
    “…Limitations include the relatively short study duration of only 1 year and the generalizability of our findings beyond the study setting. CONCLUSIONS: In this study, a primary care-based mobile health intervention integrating provider-centered and patient-facing technology was effective in reducing BP and improving stroke secondary prevention in a resource-limited rural setting in China. …”
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    Effectiveness of a primary care-based integrated mobile health intervention for stroke management in rural China (SINEMA): A cluster-randomized controlled trial
  10. 76050
    “…Our investigation, for the first time, revealed that evaluating the plasma concentration of some immune checkpoints may help prognosticate survival in mGIST patients, suggesting their potential use as prognostic biomarkers beyond the presence of KIT exon 11 Del or Delins at codons 557/558.…”
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    Prognostic Role of Plasma PD-1, PD-L1, pan-BTN3As and BTN3A1 in Patients Affected by Metastatic Gastrointestinal Stromal Tumors: Can Immune Checkpoints Act as a Sentinel for Short-Term Survival?
  11. 76051
    “…BACKGROUND: In an effort to prevent and reduce the prevalence rate of people with obesity and diabetes, South Africa implemented a sugar-content-based tax called the Health Promotion Levy in April 2018, one of the first sugar-sweetened beverage (SSB) taxes to be based on each gram of sugar (beyond 4 g/100 ml). This before-and-after study estimated changes in taxed and untaxed beverage intake 1 year after the tax, examining separately, to our knowledge for the first time, the role of reformulation distinct from behavioral changes in SSB intake. …”
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    Taxed and untaxed beverage intake by South African young adults after a national sugar-sweetened beverage tax: A before-and-after study
  12. 76052
    “…Seven (70%) of ten patients with confirmed COVID-19 had antibody positivity beyond 30 weeks from disease onset. INTERPRETATION: Most patients with SLE and confirmed COVID-19 were able to produce and maintain a serological response despite the use of a variety of immunosuppressants, providing reassurance about the efficacy and durability of humoral immunity and possible protection against re-infection with SARS-CoV-2. …”
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    Evaluation of SARS-CoV-2 IgG antibody reactivity in patients with systemic lupus erythematosus: analysis of a multi-racial and multi-ethnic cohort
  13. 76053
    “…METHODS: We explored the set of computationally predicted SARS-CoV-2 HLA-I and HLA-II ligands, examining protein source, concurrent human/murine coverage, and population coverage. Beyond MHC affinity, T cell vaccine candidates were further refined by predicted immunogenicity, sequence conservation, source protein abundance, and coverage of high frequency HLA alleles. …”
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    Landscape and selection of vaccine epitopes in SARS-CoV-2
  14. 76054
    “…This early experience will inform the development of a robust and equitable telerehabilitation model beyond the COVID-19 pandemic.…”
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    Telerehabilitation for Lung Transplant Candidates and Recipients During the COVID-19 Pandemic: Program Evaluation
  15. 76055
    “…The quality scores of most of studies were beyond 4 points (91.49%). The pooled incidence of CHE of Chinese residents in the last two decades was 23.3% (95% CI: 21.1 to 25.6%). …”
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    Economic status and catastrophic health expenditures in China in the last decade of health reform: a systematic review and meta-analysis
  16. 76056
    “…Novel gene variants detected in the CYP21A2, NR0B1, AAAS and NNT genes expanded the genetic spectrum of PAI, however, further improvement of genetic testing tools beyond our protocol are still needed to uncover the complete aetiology of PAI in children. …”
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    Genetic aetiology of primary adrenal insufficiency in Chinese children
  17. 76057
    “…Suggestive of early response, we hypothesised that continuing anti-PD-1 treatment beyond 1 year in progression-free patients may be unnecessary and so designed the DANTE trial. …”
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    The DANTE trial protocol: a randomised phase III trial to evaluate the Duration of ANti-PD-1 monoclonal antibody Treatment in patients with metastatic mElanoma
  18. 76058
    “…Key interventions will need to be implemented at KATH and possibly other tertiary healthcare facilities in Ghana and beyond to improve EIBF rate and time to breastfeeding. …”
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    Timing of initiation of breastfeeding and its determinants at a tertiary hospital in Ghana: a cross-sectional study
  19. 76059
    “…Within the FGR group, outcomes were similar between twins and singletons and, in those who survived beyond 2 years, outcomes were similar between fetuses with absent and those with reversed end‐diastolic flow in the umbilical artery. …”
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    Infant outcome after active management of early‐onset fetal growth restriction with absent or reversed umbilical artery blood flow
  20. 76060
    “…In resource-limited settings, rotavirus vaccination in the national immunization program has important cost implications, and evidence for protection beyond the first year of life and against the evolving variety of rotavirus strains is important. …”
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    Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial
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