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  1. 76081
    “…In children who were retested, the median time of a positive PCR result was 16 days (range 1–70 days), but 12.7% of patients were positive beyond day + 20. The length of viral PCR positivity correlated with the absolute neutrophil count at diagnosis. …”
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    COVID-19 in pediatric cancer patients is associated with treatment interruptions but not with short-term mortality: a Polish national study
  2. 76082
    “…The same method was applied for determining the age at which vestibular function declined beyond the limits of BVP, as defined by the Barany Society. …”
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    Genotype-Phenotype Correlation Study in a Large Series of Patients Carrying the p.Pro51Ser (p.P51S) Variant in COCH (DFNA9) Part II: A Prospective Cross-Sectional Study of the Vestibular Phenotype in 111 Carriers
  3. 76083
    “…While these reports have provided evidence for consequences of injury that extend beyond the joint, there is a paucity of studies exploring the link between nervous system functioning and patient-reported measures of disability. …”
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    Neural Markers of Knee Disability in Patients with Anterior Cruciate Ligament Reconstruction: A Multicenter fMRI Study (108)
  4. 76084
    “…Persistent AKI was defined as a composite outcome of continuance of AKI defined by the Kidney Disease Improving Global Outcomes (KDIGO) stage 2 or 3 beyond 48 h from AKI onset, progression of AKI from either KDIGO stage 0 or 1 to a worse stage, need of renal replacement therapy or death. …”
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    Serial urinary neutrophil gelatinase associated lipocalin in pediatric diabetic ketoacidosis with acute kidney injury
  5. 76085
    “…However, the only factor that significantly influenced the K-STARTS score beyond the minimal detectable change threshold (previously determined to be 3.3 points) was the completion of the additional RTS program. …”
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    Factors Influencing the Outcomes of a Validated Return to Sports Test Battery After ACL Reconstruction: A Retrospective Analysis of 676 Patients (187)
  6. 76086
    “…METHODS: We collected data from 726 unique participants (PD: 262/726, 36.1% were women; non-PD: 464/726, 63.9% were women; average age 61 years) from all over the United States and beyond. A small portion of the data (approximately 54/726, 7.4%) was collected in a laboratory setting to compare the performance of the models trained with noisy home environment data against high-quality laboratory-environment data. …”
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    Detecting Parkinson Disease Using a Web-Based Speech Task: Observational Study
  7. 76087
    “…By modeling on late assessment beyond 2 years, TT versus CR was not significantly associated with changes of fatigue-free or pain-free scores but was associated with a significant 8.9% improvement of freedom from dyspnea, P = 0.035. …”
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    Cardiopulmonary-related patient-reported outcomes in a randomized clinical trial of radiation therapy for breast cancer
  8. 76088
    “…Cerebral oxygenation parameters, beyond 02Hbc during P1 did not differ between groups, suggesting that the during acute hypoxia, an increase in cerebral 02 consumption, coupled with increased peripheral 02 utilization does seem to play a role in OI risk during SHHOC. …”
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    Orthostatic Resiliency During Successive Hypoxic, Hypoxic Orthostatic Challenge: Successful vs. Unsuccessful Cardiovascular and Oxygenation Strategies
  9. 76089
    “…We identified an aberrant gain-of-methylation region (2.2 kb in size beyond the CpG island and GGC repeats) in asymptomatic fathers. …”
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    Father-to-offspring transmission of extremely long NOTCH2NLC repeat expansions with contractions: genetic and epigenetic profiling with long-read sequencing
  10. 76090
    “…CONCLUSION: COVID-19 patients have increased subsequent risks of life-threatening secondary infections, to an equal extent or beyond risk elevations observed for patients with seasonal influenza. …”
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    COVID-19 and risk of subsequent life-threatening secondary infections: a matched cohort study in UK Biobank
  11. 76091
    “…Most existing studies and literature are limited to using transmission proton beams at ultra-high dose rates, resulting in unnecessary irradiation exposure to normal tissues beyond the target volume. By combining a new hardware design (universal range shifter and range compensator) and an inverse planning system, the novel Bragg peak method makes the Bragg-peak-based FLASH planning possible. …”
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    A Novel Proton Pencil Beam Scanning FLASH RT Delivery Method Enables Optimal OAR Sparing and Ultra-High Dose Rate Delivery: A Comprehensive Dosimetry Study for Lung Tumors
  12. 76092
    “…In survival analysis, corticosteroid treatment at ICU admission was associated with short-term survival benefit (HR 0.53; 95% CI 0.39–0.72), although beyond the 17th day of admission, this effect switched and there was an increased ICU mortality (long-term HR 1.68; 95% CI 1.16–2.45). …”
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    Corticosteroid treatment and mortality in mechanically ventilated COVID-19-associated acute respiratory distress syndrome (ARDS) patients: a multicentre cohort study
  13. 76093
    “…This Phase 3 randomized, double-blind, placebo-controlled trial investigated the efficacy and safety of lenzilumab to improve the likelihood of survival without invasive mechanical ventilation (SWOV), beyond available treatments. METHODS: Hypoxic patients, hospitalized with COVID-19 (n=520), requiring supplemental oxygen, but not invasive mechanical ventilation, were randomized on Day 0 to receive lenzilumab (1800mg, n=261) or placebo (n=259), and available treatments, including remdesivir and/or corticosteroids; and were followed through Day 28. …”
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    40. Lenzilumab Efficacy and Safety in Newly Hospitalized COVID-19 Subjects: Results From a Phase 3 Randomized Double-Blind Placebo-Controlled Trial
  14. 76094
    “…The Sisaket outbreak response serves as an example of how civilian and military public health systems can collaborate to advance national malaria elimination goals in Southeast Asia and beyond.…”
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    Civilian-military malaria outbreak response in Thailand: an example of multi-stakeholder engagement for malaria elimination
  15. 76095
    “…Rapid adoption and real-world dissemination of evidence-based mobile health interventions such as CORE are needed if we are to shorten the science-to-service gap and address the significant unmet mental health needs of people with SMI during the COVID-19 pandemic and beyond. TRIAL REGISTRATION: ClinicalTrials.gov NCT04068467; https://clinicaltrials.gov/ct2/show/NCT04068467…”
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    A Smartphone Intervention for People With Serious Mental Illness: Fully Remote Randomized Controlled Trial of CORE
  16. 76096
    “…With the increasing application of multigene panels, testing for genes beyond BRCA1/2 has become more prevalent. However, the non-BRCA mutation status of Chinese high-risk breast cancer patients has not been fully explored. …”
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    Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing Suggestions
  17. 76097
    “…The MDPP identified previously unknown CVD and T2D risk factors but does not appear to increase engagement with behaviour change beyond a standard BCPP amongst women attending breast screening. …”
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    Testing a breast cancer prevention and a multiple disease prevention weight loss programme amongst women within the UK NHS breast screening programme—a randomised feasibility study
  18. 76098
    “…SIMPLE SUMMARY: Solving biodiversity loss and climate change are part of the same problem; intact natural habitats can provide powerful and efficient climate mitigation if protected. Beyond the land (forests), there is little appreciation of just how important ocean nature is to climate mitigation. …”
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    Climate Mitigation through Biological Conservation: Extensive and Valuable Blue Carbon Natural Capital in Tristan da Cunha’s Giant Marine Protected Zone
  19. 76099
    “…It would thus be reasonable to expect immature platelet fraction (IPF) and immature platelet count (IPC) to be predictive biomarkers of thrombosis in this population. Beyond hypercoagulability, High-Sensitivity (HS) Cardiac troponin-I can be a biomarker of inflammation and may also be predictive of thrombotic events in COVID-19. …”
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    Biomarkers for Thrombosis in COVID-19: A Role for High Sensitivity Troponin-I and Immature Platelet Fraction?
  20. 76100
    “…The net clinical benefit of extended thromboprophylaxis beyond hospitalization remains unclear. Methods We conducted a retrospective multicenter observational study of 5613 hospitalized COVID-19 patients. …”
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    Extended Thromboprophylaxis in Patients with COVID-19
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