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76361“…Social and communication barriers can exacerbate challenges with management. This extends beyond the management of physical illness but should also include a holistic approach to management of psychological distress and disability and access needs.…”
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76362por Wilkins, Deidre, Hamrén, Ulrika Wählby, Chang, Yue, Domachowske, Joseph B, Englund, Janet A, Muller, William J, Leach, Amanda, Villafana, Tonya L, Kelly, Elizabeth J“…[Figure: see text] CONCLUSION: Nirsevimab is associated with ∼10-fold higher and sustained levels of nAbs through 1 year post dose compared with palivizumab, suggesting nirsevimab may offer protection for a period beyond a typical 150-day RSV season. DISCLOSURES: Deidre Wilkins, BSC, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Ulrika Wählby Hamrén, PhD, AstraZeneca: Patent holder re. dosing|AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Yue Chang, PhD, AstraZeneca: Employee|AstraZeneca: Stocks/Bonds Joseph B. …”
Publicado 2023
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76363“…Aim of the study: Investigation, whether water-filtered infrared-A (wIRA) irradiation during moderate bicycle ergometer endurance exercise has effects especially on local fat reduction and on weight reduction beyond the effects of ergometer exercise alone. Methods: Randomised controlled study with 40 obese females (BMI 30-40 (median: 34.5), body weight 76-125 (median: 94.9) kg, age 20-40 (median: 35.5) years, isocaloric nutrition), 20 in the wIRA group and 20 in the control group. …”
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76364por Newton, John N, Briggs, Adam D M, Murray, Christopher J L, Dicker, Daniel, Foreman, Kyle J, Wang, Haidong, Naghavi, Mohsen, Forouzanfar, Mohammad H, Ohno, Summer Lockett, Barber, Ryan M, Vos, Theo, Stanaway, Jeffrey D, Schmidt, Jürgen C, Hughes, Andrew J, Fay, Derek F J, Ecob, Russell, Gresser, Charis, McKee, Martin, Rutter, Harry, Abubakar, Ibrahim, Ali, Raghib, Anderson, H Ross, Banerjee, Amitava, Bennett, Derrick A, Bernabé, Eduardo, Bhui, Kamaldeep S, Biryukov, Stanley M, Bourne, Rupert R, Brayne, Carol E G, Bruce, Nigel G, Brugha, Traolach S, Burch, Michael, Capewell, Simon, Casey, Daniel, Chowdhury, Rajiv, Coates, Matthew M, Cooper, Cyrus, Critchley, Julia A, Dargan, Paul I, Dherani, Mukesh K, Elliott, Paul, Ezzati, Majid, Fenton, Kevin A, Fraser, Maya S, Fürst, Thomas, Greaves, Felix, Green, Mark A, Gunnell, David J, Hannigan, Bernadette M, Hay, Roderick J, Hay, Simon I, Hemingway, Harry, Larson, Heidi J, Looker, Katharine J, Lunevicius, Raimundas, Lyons, Ronan A, Marcenes, Wagner, Mason-Jones, Amanda J, Matthews, Fiona E, Moller, Henrik, Murdoch, Michele E, Newton, Charles R, Pearce, Neil, Piel, Frédéric B, Pope, Daniel, Rahimi, Kazem, Rodriguez, Alina, Scarborough, Peter, Schumacher, Austin E, Shiue, Ivy, Smeeth, Liam, Tedstone, Alison, Valabhji, Jonathan, Williams, Hywel C, Wolfe, Charles D A, Woolf, Anthony D, Davis, Adrian C J“…England and the English regions are compared with the remaining constituent countries of the UK and with comparable countries in the European Union (EU) and beyond. METHODS: We extracted data from the GBD 2013 to compare mortality, causes of death, years of life lost (YLLs), years lived with a disability (YLDs), and disability-adjusted life-years (DALYs) in England, the UK, and 18 other countries (the first 15 EU members [apart from the UK] and Australia, Canada, Norway, and the USA [EU15+]). …”
Publicado 2015
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76365“…Treatment of helminth infections with antihelminthics (deworming drugs) may have benefits for people living with HIV beyond simply clearance of worm infections. This is an update of a Cochrane Review published in 2009 and we have expanded it to include outcomes of anaemia and adverse events. …”
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76366por Niculescu, A B, Le-Niculescu, H, Levey, D F, Phalen, P L, Dainton, H L, Roseberry, K, Niculescu, E M, Niezer, J O, Williams, A, Graham, D L, Jones, T J, Venugopal, V, Ballew, A, Yard, M, Gelbart, T, Kurian, S M, Shekhar, A, Schork, N J, Sandusky, G E, Salomon, D R“…In particular, HTR2A increase coupled with ARRB1 and GSK3B decreases in expression in suicidality may provide a synergistic mechanistical corrective target, as do SLC4A4 increase coupled with AHCYL1 and AHCYL2 decrease. Step 6 was to move beyond diagnostics and mechanistical risk assessment, towards providing a foundation for personalized therapeutics. …”
Publicado 2017
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76367por Slogrove, Amy L., Schomaker, Michael, Davies, Mary-Ann, Williams, Paige, Balkan, Suna, Ben-Farhat, Jihane, Calles, Nancy, Chokephaibulkit, Kulkanya, Duff, Charlotte, Eboua, Tanoh François, Kekitiinwa-Rukyalekere, Adeodata, Maxwell, Nicola, Pinto, Jorge, Seage, George, Teasdale, Chloe A., Wanless, Sebastian, Warszawski, Josiane, Wools-Kaloustian, Kara, Yotebieng, Marcel, Timmerman, Venessa, Collins, Intira J., Goodall, Ruth, Smith, Colette, Patel, Kunjal, Paul, Mary, Gibb, Diana, Vreeman, Rachel, Abrams, Elaine J., Hazra, Rohan, Van Dyke, Russell, Bekker, Linda-Gail, Mofenson, Lynne, Vicari, Marissa, Essajee, Shaffiq, Penazzato, Martina, Anabwani, Gabriel, Q. Mohapi, Edith, N. Kazembe, Peter, Hlatshwayo, Makhosazana, Lumumba, Mwita, Goetghebuer, Tessa, Thorne, Claire, Galli, Luisa, van Rossum, Annemarie, Giaquinto, Carlo, Marczynska, Magdalena, Marques, Laura, Prata, Filipa, Ene, Luminita, Okhonskaia, Liubov, Rojo, Pablo, Fortuny, Claudia, Naver, Lars, Rudin, Christoph, Le Coeur, Sophie, Volokha, Alla, Rouzier, Vanessa, Succi, Regina, Sohn, Annette, Kariminia, Azar, Edmonds, Andrew, Lelo, Patricia, Ayaya, Samuel, Ongwen, Patricia, Jefferys, Laura F., Phiri, Sam, Mubiana-Mbewe, Mwangelwa, Sawry, Shobna, Renner, Lorna, Sylla, Mariam, Abzug, Mark J., Levin, Myron, Oleske, James, Chernoff, Miriam, Traite, Shirley, Purswani, Murli, Chadwick, Ellen G., Judd, Ali, Leroy, Valériane“…All children infected with HIV who entered care before age 10 years, were not known to have horizontally acquired HIV, and were followed up beyond age 10 years were included in this analysis conducted from May 2016 to January 2017. …”
Publicado 2018
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76368Publicado 2018“…Stagnating or minimal improvements experienced by several low-middle to high-middle SDI countries could reflect the complexities of re-orienting both primary and secondary health-care services beyond the more limited foci of the Millennium Development Goals. …”
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76369Publicado 2018“…To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. …”
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76370“…The modelled covariate results confirmed that the patterns of FGM/C differ markedly with region of residence and age remaining significant risk factors in both surveys, suggesting that community factors (convention theory), above and beyond individual factors, play a crucial role in the perpetuation, spread or decline of the practice of FGM/C. …”
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76371por Nievergelt, Caroline M., Maihofer, Adam X., Klengel, Torsten, Atkinson, Elizabeth G., Chen, Chia-Yen, Choi, Karmel W., Coleman, Jonathan R. I., Dalvie, Shareefa, Duncan, Laramie E., Gelernter, Joel, Levey, Daniel F., Logue, Mark W., Polimanti, Renato, Provost, Allison C., Ratanatharathorn, Andrew, Stein, Murray B., Torres, Katy, Aiello, Allison E., Almli, Lynn M., Amstadter, Ananda B., Andersen, Søren B., Andreassen, Ole A., Arbisi, Paul A., Ashley-Koch, Allison E., Austin, S. Bryn, Avdibegovic, Esmina, Babić, Dragan, Bækvad-Hansen, Marie, Baker, Dewleen G., Beckham, Jean C., Bierut, Laura J., Bisson, Jonathan I., Boks, Marco P., Bolger, Elizabeth A., Børglum, Anders D., Bradley, Bekh, Brashear, Megan, Breen, Gerome, Bryant, Richard A., Bustamante, Angela C., Bybjerg-Grauholm, Jonas, Calabrese, Joseph R., Caldas- de- Almeida, José M., Dale, Anders M., Daly, Mark J., Daskalakis, Nikolaos P., Deckert, Jürgen, Delahanty, Douglas L., Dennis, Michelle F., Disner, Seth G., Domschke, Katharina, Dzubur-Kulenovic, Alma, Erbes, Christopher R., Evans, Alexandra, Farrer, Lindsay A., Feeny, Norah C., Flory, Janine D., Forbes, David, Franz, Carol E., Galea, Sandro, Garrett, Melanie E., Gelaye, Bizu, Geuze, Elbert, Gillespie, Charles, Uka, Aferdita Goci, Gordon, Scott D., Guffanti, Guia, Hammamieh, Rasha, Harnal, Supriya, Hauser, Michael A., Heath, Andrew C., Hemmings, Sian M. J., Hougaard, David Michael, Jakovljevic, Miro, Jett, Marti, Johnson, Eric Otto, Jones, Ian, Jovanovic, Tanja, Qin, Xue-Jun, Junglen, Angela G., Karstoft, Karen-Inge, Kaufman, Milissa L., Kessler, Ronald C., Khan, Alaptagin, Kimbrel, Nathan A., King, Anthony P., Koen, Nastassja, Kranzler, Henry R., Kremen, William S., Lawford, Bruce R., Lebois, Lauren A. M., Lewis, Catrin E., Linnstaedt, Sarah D., Lori, Adriana, Lugonja, Bozo, Luykx, Jurjen J., Lyons, Michael J., Maples-Keller, Jessica, Marmar, Charles, Martin, Alicia R., Martin, Nicholas G., Maurer, Douglas, Mavissakalian, Matig R., McFarlane, Alexander, McGlinchey, Regina E., McLaughlin, Katie A., McLean, Samuel A., McLeay, Sarah, Mehta, Divya, Milberg, William P., Miller, Mark W., Morey, Rajendra A., Morris, Charles Phillip, Mors, Ole, Mortensen, Preben B., Neale, Benjamin M., Nelson, Elliot C., Nordentoft, Merete, Norman, Sonya B., O’Donnell, Meaghan, Orcutt, Holly K., Panizzon, Matthew S., Peters, Edward S., Peterson, Alan L., Peverill, Matthew, Pietrzak, Robert H., Polusny, Melissa A., Rice, John P., Ripke, Stephan, Risbrough, Victoria B., Roberts, Andrea L., Rothbaum, Alex O., Rothbaum, Barbara O., Roy-Byrne, Peter, Ruggiero, Ken, Rung, Ariane, Rutten, Bart P. F., Saccone, Nancy L., Sanchez, Sixto E., Schijven, Dick, Seedat, Soraya, Seligowski, Antonia V., Seng, Julia S., Sheerin, Christina M., Silove, Derrick, Smith, Alicia K., Smoller, Jordan W., Sponheim, Scott R., Stein, Dan J., Stevens, Jennifer S., Sumner, Jennifer A., Teicher, Martin H., Thompson, Wesley K., Trapido, Edward, Uddin, Monica, Ursano, Robert J., van den Heuvel, Leigh Luella, Van Hooff, Miranda, Vermetten, Eric, Vinkers, Christiaan H., Voisey, Joanne, Wang, Yunpeng, Wang, Zhewu, Werge, Thomas, Williams, Michelle A., Williamson, Douglas E., Winternitz, Sherry, Wolf, Christiane, Wolf, Erika J., Wolff, Jonathan D., Yehuda, Rachel, Young, Ross McD., Young, Keith A., Zhao, Hongyu, Zoellner, Lori A., Liberzon, Israel, Ressler, Kerry J., Haas, Magali, Koenen, Karestan C.“…These results demonstrate the role of genetic variation in the biology of risk for PTSD and highlight the necessity of conducting sex-stratified analyses and expanding GWAS beyond European ancestry populations.…”
Publicado 2019
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76372“…This greatly expands the educational reach that the CTSA education programs can have, moving beyond hub-focused or consortium-focused education to a much broader audience. …”
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76373“…To Increase participation of children, especially those who are disproportionately underrepresented, in clinical research in the Western New York region and beyond. METHODS/STUDY POPULATION: The University at Buffalo Clinical Translational Science Institute conducted meetings in schools, community coalitions while holding focus groups with children with chronic conditions and their families and community health workers to identify the general perceptions of research. …”
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76374por Mellor, David J.“…They are (1) sufficient neurological maturity to support minimal functional activity in specific sensory receptor systems in utero; (2) the presence of sensory stimuli that activate their aligned receptors before birth; (3) the neurological capability for entrained functions within specific sensory modalities to be retained beyond birth; (4) specific sensory stimuli that are effective both before and after birth; and (5) a capability to detect those stimuli when or if they are presented after birth in ways that differ (e.g., in air) from their presentation via fluid media before birth. …”
Publicado 2019
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76375por Angelopoulos, V., Tsai, E., Bingley, L., Shaffer, C., Turner, D. L., Runov, A., Li, W., Liu, J., Artemyev, A. V., Zhang, X.-J., Strangeway, R. J., Wirz, R. E., Shprits, Y. Y., Sergeev, V. A., Caron, R. P., Chung, M., Cruce, P., Greer, W., Grimes, E., Hector, K., Lawson, M. J., Leneman, D., Masongsong, E. V., Russell, C. L., Wilkins, C., Hinkley, D., Blake, J. B., Adair, N., Allen, M., Anderson, M., Arreola-Zamora, M., Artinger, J., Asher, J., Branchevsky, D., Capitelli, M. R., Castro, R., Chao, G., Chung, N., Cliffe, M., Colton, K., Costello, C., Depe, D., Domae, B. W., Eldin, S., Fitzgibbon, L., Flemming, A., Fox, I., Frederick, D. M., Gilbert, A., Gildemeister, A., Gonzalez, A., Hesford, B., Jha, S., Kang, N., King, J., Krieger, R., Lian, K., Mao, J., McKinney, E., Miller, J. P., Norris, A., Nuesca, M., Palla, A., Park, E. S. Y., Pedersen, C. E., Qu, Z., Rozario, R., Rye, E., Seaton, R., Subramanian, A., Sundin, S. R., Tan, A., Turner, W., Villegas, A. J., Wasden, M., Wing, G., Wong, C., Xie, E., Yamamoto, S., Yap, R., Zarifian, A., Zhang, G. Y.“…Routine data captures starting in February 2020 and lasting for at least another year, approximately the remainder of the mission lifetime, are expected to provide a very rich dataset to address questions even beyond the primary mission science objective.…”
Publicado 2020
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76376“…There are limitations in treatment beyond corticosteroid, although DMARD therapy with methotrexate being favoured in case reports listed elsewhere. …”
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76377“…CONTRIBUTION: Study findings offer new insights into MD-PhD students’ reasons for leaving the program, beyond what is known about program attrition based on retrospective analysis of existing national data, as little is known about students’ actual reasons for attrition. …”
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76378por Leon, Natalie, Balakrishna, Yusentha, Hohlfeld, Ameer, Odendaal, Willem A, Schmidt, Bey-Marrié, Zweigenthal, Virginia, Anstey Watkins, Jocelyn, Daniels, Karen“…There is a gap in interventions studying information support beyond clinical management, such as for human resources, finances, drug supply and governance. …”
Publicado 2020
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76379por Gurol-Urganci, Ipek, Jardine, Jennifer E., Carroll, Fran, Draycott, Tim, Dunn, George, Fremeaux, Alissa, Harris, Tina, Hawdon, Jane, Morris, Edward, Muller, Patrick, Waite, Lara, Webster, Kirstin, van der Meulen, Jan, Khalil, Asma“…Study outcomes were fetal death at or beyond 24 weeks’ gestation (stillbirth), preterm birth (<37 weeks’ gestation), small for gestational age infant (small for gestational age; birthweight at the <tenth centile), preeclampsia or eclampsia, induction of labor, mode of birth, specialist neonatal care, composite neonatal adverse outcome indicator, maternal and neonatal length of hospital stay after birth (3 days or more), and 28-day neonatal and 42-day maternal hospital readmission. …”
Publicado 2021
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76380por Tsirigotis, Panagiotis, Gkirkas, Konstantinos, Kitsiou, Vassiliki, Chondropoulos, Spiros, Athanassiades, Theofilos, Thomopoulos, Thomas, Tsirogianni, Alexandra, Stamouli, Maria, Karagiannidi, Aggeliki, Siafakas, Nikolaos, Pappa, Vassiliki, Nagler, Arnon“…Twenty-three patients were in CR1, all with unfavorable genetic features; 12 patients were in CR2 or beyond; and 9 patients had refractory disease at the time of transplant. …”
Publicado 2021
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