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61“…Cells which have decreased levels of the targets BMX and SOX1 also display loss of STAT3 activity. …”
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62por Yu, Yu-Wen, Hsieh, Tsung-Hsun, Chen, Kai-Yun, Wu, John Chung-Che, Hoffer, Barry J., Greig, Nigel H., Li, Yazhou, Lai, Jing-Huei, Chang, Cheng-Fu, Lin, Jia-Wei, Chen, Yu-Hsin, Yang, Liang-Yo, Chiang, Yung-Hsiao“…In addition, GIP mitigated mTBI-induced neuroinflammatory changes on GFAP, APP, and BMX protein levels. These findings suggest GIP has significant benefits in managing mTBI-related symptoms and represents a novel strategy for mTBI treatment.…”
Publicado 2016
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63por Chaiswing, Luksana, Yarana, Chontida, St. Clair, William, Tovmasyan, Artak, Batinic-Haberle, Ines, Spasojevic, Ivan, St. Clair, Daret“…Our goal was to study how ovarian cell growth depends upon the redox state of the cell; hence, we used MnP (BMX-001), a redox-active MnSOD mimetic, as a molecular tool to alter ovarian cancer redox state. …”
Publicado 2022
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64por Kliskey, Andrew (Anaru), Williams, Paula, Alessa, Lilian (Naia), Abatzoglou, John, Powell, James, McCarthy, Molly, Trammell, Jamie, Rinella, Daniel J.“…The integrated dataset is available on Mendeley (http://dx.doi.org/10.17632/cjfxg84bmx.1).…”
Publicado 2018
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65por Li, Dandan, Mullinax, John E., Aiken, Taylor, Xin, Hongwu, Wiegand, Gordon, Anderson, Andrew, Thorgeirsson, Snorri, Avital, Itzhak, Rudloff, Udo“…Non-canonical EGF (epidermal growth factor)-mediated signal transduction emerged as the top upregulated network in LRCC compared to non-LRCC, and knock down of EGF signaling effectors PDPK1 (3-phosphoinositide dependent protein kinase-1), BMX (BMX non-receptor tyrosine kinase), and NTRK2 (neurotrophic receptor tyrosine kinase 2) or treatment with PDPK1 inhibitors increased growth inhibition and induction of apoptosis in response to gemcitabine. …”
Publicado 2018
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66“…This report presents the case of a 30-year-old motocross (BMX) cyclist with a third-degree posterior cruciate ligament rupture. …”
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67por Ciccarelli, Carmela, Vulcano, Francesca, Milazzo, Luisa, Gravina, Giovanni Luca, Marampon, Francesco, Macioce, Giampiero, Giampaolo, Adele, Tombolini, Vincenzo, Di Paolo, Virginia, Hassan, Hamisa Jane, Zani, Bianca Maria“…ERK1/2, myogenic markers, proteins of DNA repair and bone marrow X-linked kinase (BMX) expression were evaluated by immunoblotting analysis. …”
Publicado 2016
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68“…One year later, the patient has no hip pain, no joint limitation, and can practice BMX at a high level again. The purpose of this report is to make the physicians aware of this rare problem that may be damaging for hip function, especially in young people.…”
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69por Wang, Peng, Li, Ying, Yan, Baihui, Yang, Zhong, Li, Litao, Cao, Zhipeng, Li, Xuan, Batinic-Haberle, Ines, Spasojevic, Ivan, Warner, David S., Sheng, Huaxin“…Our study is a randomized and blinded preclinical assessment of the efficacy of the Mn porphyrin compound, MnTnBuOE-2-PyP(5+) (BMX-001), commonly known as a superoxide dismutase mimic, in both mouse and rat models of cardiac arrest and resuscitation. …”
Publicado 2022
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70por Goraczko, Agata, Zurek, Grzegorz, Lachowicz, Maciej, Kujawa, Katarzyna, Blach, Wiesław, Zurek, Alina“…A three-times World Champion in BMX (an acronym for Bicycle Motocross) dirt jumps, a Junior World Champion in ski jumping, and a European karate Champion sustained spinal cord injuries at the cervical and thoracic level. …”
Publicado 2020
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71por Soares, Rita B., Manguinhas, Rita, Costa, João G., Saraiva, Nuno, Gil, Nuno, Rosell, Rafael, Camões, Sérgio P., Batinic-Haberle, Ines, Spasojevic, Ivan, Castro, Matilde, Miranda, Joana P., Guedes de Pinho, Paula, Fernandes, Ana S., Oliveira, Nuno G.“…MnTnBuOE-2-PyP(5+) (MnBuOE, BMX-001) is a redox-active Mn porphyrin-based drug, and a mimic of superoxide dismutase, that is currently in clinical trials for several types of cancer. …”
Publicado 2023
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72“…Of note, BMX is a specialized form of cycling that is performed on motocross tracks and affords high technical skills. …”
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73por Lin, Andy, Deatherage Kaiser, Brooke L, Hutchison, Janine R, Bilmes, Jeffrey A, Noble, William Stafford“…AVAILABILITY AND IMPLEMENTATION: The MS1Connect software is available at https://github.com/bmx8177/MS1Connect. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.…”
Publicado 2023
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74por Barreto da Silva, Felipe, Muller, Cristiane, Bello, Vinicius Henrique, Watanabe, Luís Fernando Maranho, Rossitto De Marchi, Bruno, Fusco, Lucas Machado, Ribeiro-Junior, Marcos Roberto, Minozzi, Guilherme Barbosa, Vivan, Lucia Madalena, Tamai, Marco Antonio, Farias, Juliano Ricardo, Nogueira, Angélica Maria, Sartori, Maria Márcia Pereira, Krause-Sakate, Renate“…Evidence of seed transmission of CPMMV was observed in the BMX POTÊNCIA RR cultivar. These results suggest that CPMMV could have an important role in the reduction of soybean productivity in Brazil, but symptomless infections might be hiding the actual impact of this pathogen in commercial fields and infected seeds could be the primary inoculum source of the virus in the field.…”
Publicado 2020
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75“…Here, we present the case of an 83-year-old woman with recently resected colon cancer, T4aN1bMx stage IIIB. She presented to our clinic for evaluation of a right midback mass, and a punch biopsy revealed dermal involvement by invasive, poorly differentiated carcinoma with epidermoid features. …”
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76por Hsueh, Shih-Chang, Chen, Kai-Yun, Lai, Jing-Huei, Wu, Chung-Che, Yu, Yu-Wen, Luo, Yu, Hsieh, Tsung-Hsun, Chiang, Yung-Hsiao“…Furthermore, these results suggest that short-term voluntary exercise is sufficient to alleviate cognition deficits and depressive behavior in 6-OHDA lesioned rats and long-term treatment reduces the progression of motor symptoms and elevates tyrosine hydroxylase (TH), Brain-derived neurotrophic factor (BDNF), bone marrow tyrosine kinase in chromosome X (BMX) protein expression level without affecting dopaminergic (DA) neuron loss in this PD rat model.…”
Publicado 2018
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77por Bellot, Gregory Lucien, Dong, Xiaoke, Lahiri, Amitabha, Sebastin, Sandeep Jacob, Batinic-Haberle, Ines, Pervaiz, Shazib, Puhaindran, Mark Edward“…As a proof of concept and to outline the important role of SOD activity in wound healing, we replaced NPWT by the topical application of a MnSOD mimetic, Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (MnTE-2-PyP(5+), MnE, BMX-010, AEOl10113) in the rodent model. We observed that MnE is a potent wound healing enhancer as it appears to facilitate the formation of new tissue within the wound bed and consequently advances wound closure by two days, compared to the non-treated animals. …”
Publicado 2018
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78por Zheng, Min, Xiao, Shijun, Guo, Tianfu, Rao, Lin, Li, Longyun, Zhang, Zhiyan, Huang, Lusheng“…We assessed 20 methylome and transcriptome data in longissimus dorsi (LD) or testicles from Bamaxiang (BMX) and Large White pigs (LW) by deep sequencing technology. …”
Publicado 2020
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79por Yin, Zeyu, Zou, Yuanming, Wang, Dong, Huang, Xinyue, Xiong, Shengjun, Cao, Liu, Zhang, Ying, Sun, Yingxian, Zhang, Naijin“…Tec kinases, which are a subfamily of non-receptor PTKs, were originally discovered in the hematopoietic system and include five members: Tec, Btk, Itk/Emt/Tsk, Etk/Bmx, and Txk/Rlk. With the progression of modern research, certain members of the Tec family of kinases have been found to be expressed outside the hematopoietic system and are involved in the development and progression of a variety of diseases. …”
Publicado 2022
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80por Sharma, Sudha, Patel, Foram, Ara, Hosne, Bess, Ezra, Shum, Alika, Bhattarai, Susmita, Subedi, Utsab, Bell, Daquonte Sanard, Bhuiyan, Md. Shenuarin, Sun, Hong, Batinic-Haberle, Ines, Panchatcharam, Manikandan, Miriyala, Sumitra“…In this study, we determined the role of a superoxide dismutase (SOD) mimetic MnTnBuOE-2-PyP(5+) (MnP, BMX-001) on rotenone-induced 4-HNE aggresome degradation in HL-1 cardiomyocytes. …”
Publicado 2022
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