Mostrando 481 - 500 Resultados de 680 Para Buscar '"BSL"', tiempo de consulta: 0.29s Limitar resultados
  1. 481
    “…Efficient and accurate diagnosis of Hendra virus (HeV), a biosafety level 4 (BSL-4) pathogen and zoonotic disease, is of primary importance for surveillance and outbreak control in the Australian equine industry. …”
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    Rapid, sensitive, and specific, low-resource molecular detection of Hendra virus
  2. 482
    “…Marburg virus (MARV) has been a major concern since its first outbreak in 1967. Although the deadly BSL-4 pathogen has been reported in few individuals with sporadic outbreaks following 1967, its rarity commensurate the degree of disease severity. …”
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    Immunoinformatic and reverse vaccinology-based designing of potent multi-epitope vaccine against Marburgvirus targeting the glycoprotein
  3. 483
    “…Limited clinical trials and the requirement of biosafety level-4 (BSL-4) laboratories hinders experimental work to advance our understanding of EBOV and evaluation of treatment. …”
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    Evaluation of Fendiline Treatment in VP40 System with Nucleation-Elongation Process: A Computational Model of Ebola Virus Matrix Protein Assembly
  4. 484
    “…However, the extracts can be considered nontoxic according to Clarckson’s criteria because no BSL% was registered at 1200 µg/mL. The obtained data reveal that all three extracts are safe for human use and suitable for incorporation in further pharmaceutical formulations.…”
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    Cytotoxicity Analysis and In Silico Studies of Three Plant Extracts with Potential Application in Treatment of Endothelial Dysfunction
  5. 485
    “…The RNA replicon was propagation-defective, allowing its use in BSL-2 conditions to analyze viral RNA synthesis. …”
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    Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis
  6. 486
    por Nakayama, Eri, Saijo, Masayuki
    Publicado 2013
    “…Ebolavirus and marburgvirus are classified as biosafety level-4 (BSL-4) pathogens and Category A agents, for which the US government requires preparedness in case of bioterrorism. …”
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    Animal models for Ebola and Marburg virus infections
  7. 487
    “…The isolates of fungi were ranked in the appropriate classes of biosafety BSL. RESULTS: The most frequently isolated fungi from organic rye grain, regardless of the media used, were species: Aureobasidium pullulans and Alternaria alternata. …”
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    Rye grains and the soil derived from under the organic and conventional rye crops as a potential source of biological agents causing respiratory diseases in farmers
  8. 488
    “…The CV risk factors like blood pressure (BP), blood sugar level (BSL), lipid profile, body mass index (BMI) were assessed and compared; demography of CV risk factors was also studied. …”
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    A cohort study to evaluate cardiovascular risk of selective and nonselective cyclooxygenase inhibitors (COX-Is) in arthritic patients attending orthopedic department of a tertiary care hospital
  9. 489
    “…The baboon virus isolate provides a reliable BSL2 model of viral hemorrhagic fever disease in macaques.…”
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    A simian hemorrhagic fever virus isolate from persistently infected baboons efficiently induces hemorrhagic fever disease in Japanese macaques
  10. 490
    “…We propose an alternative structure in the 5′ UTR, conserved secondary structures of 5B stem–loop (SL)1 and 5BSL2, and four possible structures of the X-tail at the very 3′ end of the HCV genome. …”
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    Conserved RNA secondary structures and long-range interactions in hepatitis C viruses
  11. 491
    “…An indirect hemagglutination assay (IHA) is widely used for serodiagnosis, but it has a short shelf life, is poorly standardized, and requires a viable bacteria culture performed in a biosafety level 3 (BSL-3) laboratory. To improve the diagnostic methods, we have developed two rapid latex agglutination tests based on purified B. pseudomallei O-polysaccharide (OPS) and capsular polysaccharide (CPS) antigens. …”
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    Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei
  12. 492
    “…These findings are highly significant as they expand our understanding of host mechanisms that may broadly control enveloped RNA virus budding, and they establish Orai and STIM1 as novel targets for broad-spectrum host-oriented therapeutics to combat these emerging BSL-4 pathogens and potentially other enveloped RNA viruses that bud via similar mechanisms.…”
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    Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention
  13. 493
    “…LEEI can be used in normal laboratories, including good manufacturing practice (GMP)- or high biosafety level (BSL)-environments, as only minor shielding is necessary. …”
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    Pathogens Inactivated by Low-Energy-Electron Irradiation Maintain Antigenic Properties and Induce Protective Immune Responses
  14. 494
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    Stress, stress‐induced cortisol responses, and eyewitness identification performance
  15. 495
    “…Prefrontal cortex and hippocampal samples were collected at 20‐weeks of age (BSL n = 11) and at 33‐weeks of age (AGE and AGE‐HFS). …”
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    Evaluation of neuropathological effects of a high‐fat high‐sucrose diet in middle‐aged male C57BL6/J mice
  16. 496
    por Sherwood, Laura J., Hayhurst, Andrew
    Publicado 2019
    “…The sdAb–APEX2 fusions also enabled live Marburgvirus and Ebolavirus detection 24 h post-infection of Vero E6 cells within a BSL-4 laboratory setting. The simple and inexpensive mining of large amounts of periplasmic sdAb–APEX2 fusion proteins should help advance studies of past, contemporary, and perhaps Filovirus species yet to be discovered.…”
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    Periplasmic Nanobody-APEX2 Fusions Enable Facile Visualization of Ebola, Marburg, and Mĕnglà virus Nucleoproteins, Alluding to Similar Antigenic Landscapes among Marburgvirus and Dianlovirus
  17. 497
    “…After digestion of the amplification products with restriction enzymes (AluI, BslI, HaeIII, and MspI), terminal restriction fragments (T-RFs) of DNA were detected. …”
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    Characteristics of Gut Microbiota in Patients With Diabetes Determined by Data Mining Analysis of Terminal Restriction Fragment Length Polymorphisms
  18. 498
    “…This prime-boost vaccine could also protect mice from the simulated infection with EBOV-like particle (EBOVLP) in biosafety level 2 (BSL-2) laboratories, and antibodies from the prime-boost immunized rhesus macaques could passively provide protection against EBOVLP infection. …”
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    Chimpanzee adenoviral vector prime-boost regimen elicits potent immune responses against Ebola virus in mice and rhesus macaques
  19. 499
    “…It is classified as a Biosafety Level-4 (BSL-4) agent. The case-fatality varies from 40% to 70% depending on the severity of the disease and on the availability of adequate healthcare facilities. …”
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    Molecular epidemiology and phylogeny of Nipah virus infection: A mini review
  20. 500
    “…Because of the in vivo work, the biosafety risk in ABSL-3 facilities is higher than that in BSL-3 facilities. Undoubtedly, management practices must be strengthened to ensure biosafety in the ABSL-3 facility. …”
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    Biosafety and data quality considerations for animal experiments with highly infectious agents at ABSL-3 facilities
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