Mostrando 201 - 220 Resultados de 4,367 Para Buscar '"Bach"', tiempo de consulta: 0.21s Limitar resultados
  1. 201
    por Liu, Yuan, Zheng, Yi
    Publicado 2017
    “…The results revealed that the Bach1 mRNA and protein levels were significantly downregulated by Bach1 siRNA. …”
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  2. 202
    “…BTB and CNC Homology 1 Basic Leucine Zipper Transcription Factor 2 (BACH2) is a suppressor of transcription. The BACH2–BCL6 balance controls selection at the pre-B cell receptor checkpoint by regulating p53 expression. …”
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  3. 203
    “…CONCLUSIONS: Theraputic effects of PFD for IPF were involved in Nrf2/Bach1 equilibrium which regulated the capacity of oxidative stress. …”
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  4. 204
  5. 205
    “…Overall, the observed AMPK-mediated boost in transactivation of a subset of Nrf2 target genes involves downregulation of Bach1 and subsequent favored binding of activating Nrf2 over repressing Bach1 to the examined ARE sites.…”
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  6. 206
    “…Mechanistic characterizations indicated that Bach2 deletion facilitated DNA repair in intestinal crypt cells, as evidenced by faster resolution of γ-H2AX and 53BP1 foci in Bach2(−/−) crypt cells, compared with Bach2(+/+) control. …”
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  7. 207
    “…Strikingly, we identified FOS, a transcriptional activator competing with BACH2, as a novel downstream target repressed by BACH2. …”
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  8. 208
  9. 209
    por Zhou, Ninghao, Hu, Jinfeng, Hou, Jia
    Publicado 2021
    “…The simulation results show that the GS-DinkelBach algorithm can obtain precise EE gains with low computational complexity. …”
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  10. 210
    “…Transverse aortic constriction surgery was operated to induce cardiac hypertrophy and failure in mice. BACH2 was overexpressed in mice through tail vein injection of AAV9-Bach2. …”
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  11. 211
  12. 212
    Partituras Libro
  13. 213
    Partituras Libro
  14. 214
  15. 215
    “…We found that RKIP and BACH1 belong to two antagonistic ‘teams’ of players—while BACH1 belonged to the one driving pro-EMT, stem-like and therapy-resistant cell states, RKIP belonged to the one enabling pro-epithelial, less stem-like and therapy-sensitive phenotypes. …”
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  16. 216
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  18. 218
    “…Treatment with CCl(4) induced a significant dose-dependent increase in Bach1 mRNA 1–3 h after administration. Bach1 mRNA peaked at 6 h after CCl(4) treatment (1 ml/kg), followed by a rapid decrease and gradual return to baseline by 12 h after treatment. …”
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  19. 219
    “…An alternative is to target the repressor Bach1. Bach1 has an endogenous ligand, heme, that inhibits Bach1 binding to ARE, thus allowing Nrf2-mediated gene expression including that of heme-oxygenase-1 (HMOX1), a well described target of Bach1 repression. …”
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  20. 220
    “…Genes regulated by BACH2 were very significantly over-represented among our differentially expressed genes (P<2.2x10(-16)) indicating that reduced expression of this master regulator of T cell differentiation promotes a pro-inflammatory response and strongly corroborates genetic evidence that BACH2 plays an important role in CD pathogenesis.…”
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