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221“…Our analysis included all 24 Preludes and 24 Fugues from Bach’s Well-Tempered Clavier (book 1), as well as all 24 of Chopin’s Preludes for piano. …”
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222por Jang, Eunkyeong, Lee, Hye Rim, Lee, Geon Hee, Oh, Ah-Reum, Cha, Ji-Young, Igarashi, Kazuhiko, Youn, Jeehee“…The transcription repressor Bach2 has been proposed as a regulator of T cell quiescence, but the underlying mechanism is not fully understood. …”
Publicado 2017
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223por Chang, Wen-Hsin, Thai, Philip, Xu, Jihao, Yang, David C., Wu, Reen, Chen, Ching-Hsien“…In light of a pivotal role of NRF2 and BACH1 in response to oxidative stress and regulation of HO-1, we examined if smoke-induced HO-1 expression is modulated through the NRF2/BACH1 axis. …”
Publicado 2017
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224“…The protein level of BTB domain and CNC homolog 2 (Bach2) was measured by Western blotting. The interaction between miR-31 and Bach2 was verified using dual luciferase reporter assay. …”
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225“…The transcription factor Bach2 which is predominantly expressed in B and T lymphocytes represses the expression of genes by forming heterodimers with small Maf and Batf proteins and binding to the corresponding sequence on the DNA. …”
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226por Wada, Satoshi, Kanzaki, Hiroyuki, Katsumata, Yuta, Yamaguchi, Yuuki, Narimiya, Tsuyoshi, Attucks, Otis C., Nakamura, Yoshiki, Tomonari, Hiroshi“…However, it remains unknown if Bach1 inhibitors attenuate osteoclastogenesis. In this study, we hypothesized that Bach1 inhibition would exert an anti-osteoclastogenic effects via diminishing of intracellular ROS signaling through augmented antioxidation. …”
Publicado 2020
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227por Perluigi, Marzia, Tramutola, Antonella, Pagnotta, Sara, Barone, Eugenio, Butterfield, D. Allan“…This review focuses on a key element that regulates redox homeostasis, the transcription factor Nrf2, which is negatively regulated by BACH1, encoded on chromosome 21. The role of the Nrf2/BACH1 axis in DS is under investigation, and the effects of triplicated BACH1 on the transcriptional regulation of Nrf2 are still unknown. …”
Publicado 2020
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228por Wang, Xinxing, Xue, Bingjian, Zhang, Yujie, Guo, Guangcheng, Duan, Xin, Dou, Dongwei“…In TNBC cell lines, circBACH2 knockdown suppressed the malignant progression of TNBC cells. …”
Publicado 2021
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229por Hushpulian, Dmitry M., Ammal Kaidery, Navneet, Ahuja, Manuj, Poloznikov, Andrey A., Sharma, Sudarshana M., Gazaryan, Irina G., Thomas, Bobby“…A potentially promising and alternative therapeutic approach to overcome this non-specificity emerging from targeting Keap1 is to inhibit the Nrf2 repressor Bach1 for constitutive activation of the Nrf2 pathway and bypass the Keap1-Nrf2 complex.…”
Publicado 2021
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230por Pradhan, Pooja, Vijayan, Vijith, Cirksena, Karsten, Buettner, Falk F.R., Igarashi, Kazuhiko, Motterlini, Roberto, Foresti, Roberta, Immenschuh, Stephan“…BTB-and-CNC homologue 1 (BACH1), a heme-regulated transcription factor, mediates innate immune responses via its functional role in macrophages. …”
Publicado 2022
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231por Melazzini, Luca, Savoldi, Filippo, Chessa, Massimo, Vitali, Paolo, Zanardo, Moreno, Bertoldo, Enrico Giuseppe, Fiolo, Valentina, Griffanti, Ludovica, Carminati, Mario, Frigiola, Alessandro, Giamberti, Alessandro, Secchi, Francesco, Callus, Edward, Codari, Marina, Sardanelli, Francesco“…To better characterize this field, we launched the multi-disciplinary BACH (Brain Aging in Congenital Heart disease) San Donato study, that aimed at investigating signs of brain injury in ACHD. …”
Publicado 2022
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232“…Emerging evidence suggest a critical role of the transcription factor Bach2 in regulating Th2 immune responses. Bach2 serves as a super enhancer and transcriptional repressor to control the differentiation and maturation of Th2-related immune cells such as B cell lineages and T cell lineages. …”
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233por Li, Xue, Lu, Lihong, Hou, Wenting, Wang, Fei, Huang, Ting, Meng, Zhipeng, Zhu, Minmin“…Moreover, SET domain-containing protein 8 (SETD8), ETS-domain containing protein (ELK1) and BTB and CNC homology 1 (bach1) all participate in endothelial injury. In this study, we hypothesize that the SETD8/ELK1/bach1 functional axis is involved in mediating EndMT in diabetic nephropathy. …”
Publicado 2022
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234“…Our findings reveal Nrf2, BACH1, and ferroportin as important regulators, protecting human macrophages against ferroptosis.…”
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235por Takemoto, Kenshiro, Kobatake, Kohei, Miura, Kento, Fukushima, Takafumi, Babasaki, Takashi, Miyamoto, Shunsuke, Sekino, Yohei, Kitano, Hiroyuki, Goto, Keisuke, Ikeda, Kenichiro, Hieda, Keisuke, Hayashi, Tetsutaro, Hinata, Nobuyuki, Kaminuma, Osamu“…BACH1 involvement in other OSR‐linked pathways, including inflammatory responses, angiogenesis, and mTOR signaling, was further revealed by RNA sequencing analysis of BACH1‐knockdown cells. …”
Publicado 2022
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237por Bach, Johann Sebastian, 1685-1750“…Notenbüchlein für Anna Magdalena Bach (1725)…”
Publicado 1993
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