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  1. 3641
    por Hüsing, Anika, Kaaks, Rudolf
    Publicado 2020
    “…Using federal-wide survey and lung cancer incidence data (2008–2013), we examined the performance of four well-established risk models from the USA (PLCO(M2012), LCRAT, Bach) and the UK (LLP(2008)) in the German population, comparing with standard eligibility criteria based on age limits, minimal pack years of smoking (or combination of total duration with average intensity) and maximum years since smoking cessation. …”
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    Risk prediction models versus simplified selection criteria to determine eligibility for lung cancer screening: an analysis of German federal-wide survey and incidence data
  2. 3642
    “…Additionally, we used two public datasets, the BreakHis and BACH, for independent verification. The accuracies our model obtained on these two datasets were comparable to related publications. …”
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    Deep Learning-Based Multi-Class Classification of Breast Digital Pathology Images
  3. 3643
    “…Among them, six markers, including universal (BacUni), human-associated (HF183-1 and BacH), swine-associated (Pig-2-Bac), ruminant-associated (Rum-2-Bac), and avian-associated (AV4143) markers, performed well in the study. …”
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    Synergistic Application of Molecular Markers and Community-Based Microbial Source Tracking Methods for Identification of Fecal Pollution in River Water During Dry and Wet Seasons
  4. 3644
    “…The results obtained using images from the BACH and BreakHis databases showed that our approach obtained best performing architectures with the top-5 of the architectures yielding a significant detection rate. …”
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    A bioinspired neural architecture search based convolutional neural network for breast cancer detection using histopathology images
  5. 3645
    “…The automated plate assessment system (APAS Independence; Clever Culture System, Bäch, Switzerland) is an automated imaging station linked with interpretive software that detects target colonies of interest on chromogenic media and sorts samples as negative or presumptive positive. …”
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    Comparison of an Automated Plate Assessment System (APAS Independence) and Artificial Intelligence (AI) to Manual Plate Reading of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus CHROMagar Surveillance Cultures
  6. 3646
    “…This is potentially evoked by sustained activity of Nfix, Runx1, and Nfe2l2 and dissociation of the transcriptional repressor Bach2. Previously reported trained immunity inducers are, however, infrequently present in the host, whereas heme abundantly occurs during noninfectious and infectious disease. …”
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    Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme
  7. 3647
    por Li, Na, Zhan, Xianquan
    Publicado 2022
    “…METHODS: The Nrf2 signaling pathway-related genes that had a direct relationship with Nrf2, including ATF4, BACH1, CREBBP, CUL3, EIF2AK3, EP300, FOS, FOSL1, GSK3B, JUN, KEAP1, MAF, MAFF, MAFG, MAFK, MAPK1, MAPK3, MAPK7, MAPK8, MAPK9, PIK3CA, PRRT2, and RIT1, were selected to do a systematic pan-cancer analysis. …”
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    Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes
  8. 3648
    por Ryter, Stefan W.
    Publicado 2022
    “…The expression of HO-1 is regulated by NF-E2-related factor-2 and counter-regulated by Bach-1, in a heme-sensitive manner. Additionally, HMOX1 promoter polymorphisms have been associated with human disease. …”
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    Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders
  9. 3649
    “…METHODS: A cross-sectional and descriptive study was conducted on 231 outpatients with T2DM at Bach Mai hospital, Hanoi, Vietnam. Depression severity was measured with the Patient Health Questionnaire-9 (PHQ-9). …”
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    The Relationship Between Depression and Multifactorial Control and Microvascular Complications in Vietnamese with Type 2 Diabetes Mellitus Aged 30–60 Years
  10. 3650
    “…We validated that the C allele of rs9619311 attenuated the binding affinity of BACH2, MEIS2, NFE2L2, and PBX2 to the TIMP3 promoter, and that the G allele of rs2234921 reduced the affinity of E2F8 and RUNX1 to bind to the promoter. …”
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    TIMP3 Gene Polymorphisms of -1296 T > C and -915 A > G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and In Silico Analysis of Mutation Impacts
  11. 3651
    “…Hdac1 knock-out led to strongly perturbed protein expression of antagonistic transcription factors that govern plasma cell versus B cell identity (by decreasing IRF4 and BLIMP1 and increasing BACH2 and PAX5). DISCUSSION: Taken together, our results highlight specific and non-redundant roles for Ern1, Arf4 and Hdac1 in the early steps of plasma cell differentiation.…”
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    A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
  12. 3652
    “…Disrupted miR-155 repression of AT1R + 1166C-allele, significantly associated with adverse cardiovascular and COVID-19 outcomes, manifests its decisive role in RAAS modulation. BACH1 and SOCS1 repression creates an anti-inflammatory and cytoprotective milieu, robustly inducing antiviral interferons. …”
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    Beauty and the beast: host microRNA-155 versus SARS-CoV-2
  13. 3653
    por Cato, Liam D., Li, Rick, Lu, Henry Y., Yu, Fulong, Wissman, Mariel, Mkumbe, Baraka S., Ekwattanakit, Supachai, Deelen, Patrick, Mwita, Liberata, Sangeda, Raphael, Suksangpleng, Thidarat, Riolueang, Suchada, Bronson, Paola G., Paul, Dirk S., Kawabata, Emily, Astle, William J., Aguet, Francois, Ardlie, Kristin, de Lapuente Portilla, Aitzkoa Lopez, Kang, Guolian, Zhang, Yingze, Nouraie, Seyed Mehdi, Gordeuk, Victor R., Gladwin, Mark T., Garrett, Melanie E., Ashley-Koch, Allison, Telen, Marilyn J., Custer, Brian, Kelly, Shannon, Dinardo, Carla Luana, Sabino, Ester C., Loureiro, Paula, Carneiro-Proietti, Anna Bárbara, Maximo, Cláudia, Méndez, Adriana, Hammerer-Lercher, Angelika, Sheehan, Vivien A., Weiss, Mitchell J., Franke, Lude, Nilsson, Björn, Butterworth, Adam S., Viprakasit, Vip, Nkya, Siana, Sankaran, Vijay G.
    Publicado 2023
    “…We conduct targeted perturbations to define BACH2 as a new genetically-nominated regulator of hemoglobin switching. …”
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    Genetic regulation of fetal hemoglobin across global populations
  14. 3654
    “…Such strong associations included CD247, TPO, KIAA1524, PDE8B, BACH2, FYN, FOXK1, NKX2-3, and SPATA13. Subsequently, applying the FUMA approach, novel putative AITD susceptibility genes and involved gene sets were detected. …”
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    Identification of multiple novel susceptibility genes associated with autoimmune thyroid disease
  15. 3655
    “…TTFM treatment significantly up-regulated Slc5a8 and Arhgap9 expression compared with untreated cells. Moreover, Cybb, and Bach2os were significantly downregulated after TTFM treatment compared with untreated cells. …”
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    In vitro evaluation of the anti‑breast cancer properties and gene expression profiles of Thai traditional formulary medicine extracts
  16. 3656
    “…The two patients severely affected with ulcerative colitis exhibited a distinct profile: both carried potentially detrimental variation in the BACH2 and IL10 genes not seen in other patients. …”
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    Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
  17. 3657
    “…The induction of heme oxygenase-1 (HMOX1), the inducible isozyme in heme catabolism, is mediated via the Bach1/Nrf2 pathway, and protects livers from toxic, oxidative and inflammatory insults. …”
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    Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis
  18. 3658
    “…The young group was found to have greater gene expression of inflammatory regulatory genes at 48 h and 1-week in genes such as basic leucine zipper transcription factor 2 (BACH2), leucine-rich repeat neuronal 3 (LRRN3), and lymphoid enhancer-binding factor 1 (LEF1) compared to the old group. …”
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    Older Age Results in Differential Gene Expression after Mild Traumatic Brain Injury and Is Linked to Imaging Differences at Acute Follow-up
  19. 3659
    “…HIV DNA integrations in the oncogenes BACH2 and MKL2 that do not involve rearrangements of the viral or host DNA can stimulate the proliferation of infected cells. …”
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    Drug resistant integrase mutants cause aberrant HIV integrations
  20. 3660
    “…We screened the chromatin immunoprecipitation database ENCODE for 2 proteins, MAFK and BACH1, that bind the NFE2L2-regulated enhancer antioxidant response element (ARE). …”
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    Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes
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