“…RA patients exhibited accumulation of BTB and CNC homology 2 (BACH2), the silencing transcription factor, at the UBASH3A loci in CD4(+) T cells, but not the SE-defining factor, mediator complex subunit 1 (MED1)/bromodomain 4 (BRD4). …”
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“…Correlation analysis between mRNA expression of transcription factor genes in renal tubulointerstitium and clinical features showed that AP1, BACH1, CDC5, FAC1, FOXD1, FOXJ2, FOXO1, FOXO4, HFH1, IRF1, POU3F2, SOX5, SOX9, RSRFC4, S8 and TGIF1 may be related to diabetic tubulointerstitial injury. …”
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“…In order to investigate the mechanism involved in HO-1 induction, we verified that HPF downregulates the BTB and CNC homology 1 (BACH-1) transcription factor, an inhibitor of the heme oxygenase 1 (HMOX-1) gene transcription. …”
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“…Kim Lavoie, Co-Director, Montreal Behavioural Medicine Centre, Canada and Canada's COVID-19 Expert Advisory Panel) and WHO/Europe (Dr. Katrine Bach-Habersaat; Regional Advisor for Behavioural and Cultural Insights). …”
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“…RR, cumulative risk up to age 70, RR = 1.9; 1.1–3.9); and BRIP1 (or BACH1) P919S (SS vs. PP, cumulative risk up to age 50, RR = 6.9; 1.6–29.3). …”
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“…Abbreviations: ACTB: actin, beta, ARE: antioxidant response element; ATG5: autophagy related 5; BACH1: BTB domain and CNC homolog 1; ChIP: chromatin immunoprecipitation; CMA: chaperone-mediated autophagy; DHE: dihydroethidium; DMF: dimethyl fumarate; ENCODE: Encyclopedia of DNA elements at the University of California, Santa Cruz; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GBA: glucosylceramidase beta; GFP: green fluorescent protein; HMOX1: heme oxygenase 1; H(2)O(2): hydrogen peroxide; HSPA8/HSC70: heat shock protein family A (Hsp70) member 8; KEAP1: kelch like ECH associated protein 1; LAMP2A: lysosomal associated membrane protein 2A; LAMP2B: lysosomal associated membrane protein 2B; LAMP2C: lysosomal associated membrane protein 2C; LAMP1: lysosomal associated membrane protein 1; MAFF: MAF bZIP transcription factor F; MAFK: MAF bZIP transcription factor K; NFE2L2/NRF2: nuclear factor, erythroid derived 2, like 2; NQO1: NAD(P)H quinone dehydrogenase 1; PQ: paraquat; PI: protease inhibitors; qRT-PCR: quantitative real-time polymerase chain reaction; RNASE: ribonuclease A family member; SFN: sulforaphane; SQSTM1/p62: sequestosome 1; TBP: TATA-box binding protein…”
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“…These identified LXR, PPARα, FOXO1 and BACH1 as key transcription factors orchestrating the metabolic and oxidative stress responses to palmitate. …”
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“…METHODS: During and after the dengue season (September 2018 to January 2019), we conducted a case-control study in order to determine the risk factors for dengue fever in Hanoi city, Vietnam. 98 dengue patients and 99 patients with other acute infections, such as Hepatitis B virus infection, were recruited at Department of Infectious Disease of Bach Mai national hospital in Hanoi. Patients were interviewed using a structured questionnaire covering demographic, housing, environmental factors and knowledge, attitude, and practice on dengue prevention and control. …”
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“…In a previous report we found evidence suggesting that the DNA helicase and Fanconi Anemia repair protein, FANCJ (BRIP1/BACH1), functions to regulate meiotic recombination in mouse. …”
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“…The models outperformed the NLST eligibility criteria over a substantial range of risk thresholds in decision curve analysis, with a higher sensitivity for all models and a slightly higher specificity for some models. The PLCOm2012, Bach, and Two-Stage Clonal Expansion incidence models had the best overall performance, with AUCs >0.68 in the NLST and >0.77 in the PLCO. …”
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“…The COVID-19 tissues from people with no pre-existing dementia showed, compared to controls, 5-10× fold increases in expression of neuronal NOS and NMDAR2 as well as a marked decrease in the expression of proteins whose loss is associated with worsening Alzheimer's disease: MFSD2a, SHIP1, BCL6, BCL10, and BACH1. In COVID-19 tissues from people with dementia the widespread spike-induced microencephalitis with the concomitant microglial activation co-existed in the same areas where neurons had hyperphosphorylated tau protein suggesting that the already dysfunctional neurons were additionally stressed by the SARS-CoV2 induced microangiopathy. …”
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“…CONCLUSION: These findings suggested that low expression of GAS6-AS1 might exert an essential role in AFST through downregulating its downstream target mRNAs GOLGA8A and BACH2, and GAS6-AS1 might be a potential target for AFST therapy. …”
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“…The result of lncRNA-TF-mRNA regulatory network showed that lncRNAs such as BACH1-IT1 and SNHG15 might induce the expression of the corresponding TFs such as TFAM and THAP12 and upregulate the expression of AMPD3. …”
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“…Potential candidate genes in these regions include MAP3K7, BACH2 (6q15), GFRA1 (10q25.3), and WDR27 (6q27). …”
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“…METHODS: We conducted a cross-sectional study in the Department of Infectious Diseases, Bach Mai Hospital, Hanoi, Vietnam, from June 2012 to May 2014. …”
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“…EC number  3.6.4.12 Systematic name  ATP phosphohydrolase (DNA helix unwinding) Recommended name  DNA helicase Synonyms  3’ to 5’ DNA helicase <28> [35]  3’-5’ DNA helicase <11> [55]  3’-5’ PfDH <11> [55]  5’ to 3’ DNA helicase <26,27> [19,42]  AvDH1 <47> [37]  BACH1 helicase <19> [34]  BLM <3> [28]  BLM protein <3> [28]  BRCA1-associated C-terminal helicase <19> [34]  BcMCM <8> [52]  CeWRN-1 <43> [9]  DDX25 <3,48> [36]  DNA helicase 120 <7> [15]  DNA helicase A <4> [8]  DNA helicase E <5> [44]  DNA helicase II <9> [7]  DNA helicase III <4> [27]  DNA helicase RECQL5β <44> [17]  DNA helicase VI <3> [45]  Dbp9p <46> (<46> a member of the DEAD box protein family [24]) [24]  DmRECQ5 <1> [50]  DnaB helicase <29> [23]  E1 helicase <17> [58]  GRTH/DDX25 <3,48> [36]  HCoV SF1 helicase <23> [3]  HCoV helicase <23> [3]  HDH IV <3> [45]  Hel E <5> [44]  Hmi1p <40> [60]  MCM helicase <6,5,38> [43,54]  MCM protein <6,35> [43]  MER3 helicase <22> [30]  MER3 protein <22> [30]  MPH1 <28> [35]  NS3 <12,50> (<12,50> ambiguous [38,65,66]) [38,65,66]  NS3 NTPase/helicase <14> (<14> ambiguous [67]) [67]  NS3 protein <12> (<12> ambiguous [63]) [63]  NTPase/helicase <12,16> (<12> ambiguous [61]) [61,64]  PDH120 <7> [15]  PIF1 <33> [51]  PIF1 helicase <33> [51,53]  PcrA <37> [20]  PcrA helicase <37,41,49> [20,21,39]  PcrASpn <41> [21]  PfDH A <11> [55]  Pfh1p <27> [42]  RECQ5 <1> [49,50]  RECQ5 helicase <1> (<1> small isoform [49]) [49]  RECQL5b <44> [17]  REcQ <31> [13]  RSF1010 RepA <30> [5]  RecG <45> [6]  RecQ helicase <32> [56]  RecQsim <32> [56]  Rep52 <24> [40]  Rrm3p <26> [19]  Sgs1 <36> [29]  Sgs1 DNA helicase <36> [29]  TWINKLE <21> [33]  Tth UvrD <20> [16]  UvrD <20,42> [16,22]  UvrD helicase <39> [18]  WRN <18> [31]  WRN RecQ helicase <18> [12]  WRN helicase <18> [12]  WRN protein <18> [12]  WRN-1 RecQ helicase <43> [9]  Werner Syndrome helicase <18> [31]  Werner syndrome RecQ helicase <18> [12]  dheI I <1> [46]  dnaB <29> [23]  hPif1 <33> [53]  helicase DnaB <2> [10]  helicase II <25> [25]  helicase PcrA <49> [39]  helicase UvrD <20> [16]  helicase domain of bacteriophage T7 gene 4 protein <10> [47]  non structural protein 3 <12> (<12> ambiguous [61,62]) [61,62]  nonstructural protein 3 <12,14,50,51> (<12,14,50> ambiguous [38,63,65,66,67]; <51> ambigous [4]) [4,38,63,65,66,67]  protein NS3 <12> (<12> ambiguous [62]) [62]  scHelI <4> [26]  urvD <25> [25]…”
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“…METHODS: This prospective observational study was conducted between September 2015 and June 2017 at Bach Mai Hospital, Hanoi, Vietnam. Inclusion criteria were hospitalized patients aged ≥15 years; one or more of symptoms including shortness of breath, sore throat, runny nose, headache, and muscle pain/arthralgia in addition to cough and fever > 37.5 °C; and ≤ 10 days from the onset of symptoms. …”
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