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1041por Xu, Yun, Liu, Kai, Li, Cong, Li, Minghan, Liu, Fangqi, Zhou, Xiaoyan, Sun, Menghong, Ranganathan, Megha, Zhang, Liying, Wang, Sheng, Hu, Xin, Xu, Ye“…Mutations in HR genes, including BARD1, RAD50, and ATM, were found to increase CRC risk with odds ratios of 2.8-, 3.1-, and 3.1-fold, respectively. …”
Publicado 2023
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1042“…These technologies, such as Chat GPT and Bard, can generate new content and have a wide range of possible applications. …”
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1043por Zhang, Haoran, Zhang, Dongming, Liu, Jia, Shi, Yuequan, Liu, Xiaoyan, Chen, Minjiang, Zhong, Wei, Zhao, Jing, Xu, Yan, Wang, Mengzhao“…METHODS: We first examined 74 DDR genes involved in seven DDR pathways and then focused on six specific genes: ATM, BRCA1, BRCA2, CHEK1, BARD1, and BRIP1. A total of 179 stage I and IIIa NSCLC patients who received curative resection in Peking Union Medical College Hospital and their corresponding samples were collected for DNA sequencing, immunohistochemistry and survival analysis. …”
Publicado 2023
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1044“…On the results of RT-PCR, the expressions of Abcc9, Bard1, and Casp4 were increased, but the expressions of Lyz, Casp8, and Timp1 were decreased in the Post group compared with the Ischemic group. …”
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1045por Yaminisharif, Ahmad, Davoodi, Gholamreza, Kasemisaeid, Ali, Farahani, Ali Vasheghani, Ghazanchai, Fatemeh, Moghaddam, Mansour“…Electrocardiograms were recorded on digital multichannel systems (EP-Med) or Bard EP system. Anticoagulation was initiated during the procedure. …”
Publicado 2010
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1046por Chu, Michael J. J., Phillips, Anthony R. J., Hosking, Alexander W. G., MacDonald, Julia R., Bartlett, Adam S. J. R., Hickey, Anthony J. R.“…Here we report a method to assess MF using <3 mg of tissue obtained by a Tru-cut® biopsy needle making it suitable for percutaneous application. METHODS: An 18G Bard® Max-core® biopsy instrument was used to collect samples. …”
Publicado 2013
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1047“…BACKGROUND AND OBJECTIVES: The objective of this study was to compare mesh contracture, adhesion characteristics, tissue ingrowth, and histologic response of Ventralight ST/SorbaFix (C.R. Bard/Davol, Warwick, RI, USA) with Physiomesh/Securestrap (Ethicon, Somerville, NJ, USA) in a porcine model of laparoscopic ventral hernia repair. …”
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1048por Caleca, Laura, Putignano, Anna Laura, Colombo, Mara, Congregati, Caterina, Sarkar, Mohosin, Magliery, Thomas J., Ripamonti, Carla B., Foglia, Claudia, Peissel, Bernard, Zaffaroni, Daniela, Manoukian, Siranoush, Tondini, Carlo, Barile, Monica, Pensotti, Valeria, Bernard, Loris, Papi, Laura, Radice, Paolo“…A green fluorescent protein (GFP)-fragment reassembly assay showed that the p.Cys64Arg substitution prevents the binding of the BRCA1 protein to the interacting protein BARD1, in a similar way as proven deleterious mutations in the RING-domain. …”
Publicado 2014
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1049por Esteban-Jurado, Clara, Vila-Casadesús, Maria, Garre, Pilar, Lozano, Juan José, Pristoupilova, Anna, Beltran, Sergi, Muñoz, Jenifer, Ocaña, Teresa, Balaguer, Francesc, López-Cerón, Maria, Cuatrecasas, Miriam, Franch-Expósito, Sebastià, Piqué, Josep M., Castells, Antoni, Carracedo, Angel, Ruiz-Ponte, Clara, Abulí, Anna, Bessa, Xavier, Andreu, Montserrat, Bujanda, Luis, Caldés, Trinidad, Castellví-Bel, Sergi“…Correct family segregation and somatic studies were used to categorize the most interesting variants in CDKN1B, XRCC4, EPHX1, NFKBIZ, SMARCA4, and BARD1. CONCLUSION: We identified new potential colorectal cancer predisposition variants in genes that have a role in cancer predisposition and are involved in DNA repair and the cell cycle, which supports their putative involvement in germ-line predisposition to this neoplasm.…”
Publicado 2015
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1050por Kawamura, Yusuke, Ikeda, Kenji, Arase, Yasuji, Sorin, Yushi, Fukushima, Taito, Kunimoto, Hideo, Hosaka, Tetsuya, Kobayashi, Masahiro, Saitoh, Satoshi, Sezaki, Hitomi, Akuta, Norio, Suzuki, Fumitaka, Suzuki, Yoshiyuki, Kumada, Hiromitsu“…With regard to the utility of the FSN for predicting advanced fibrosis of NASH (stage ≥3), the area under the receiver operating characteristic curves (AUROC), 0.909 (95 % CI 0.847–0.970, p < 0.001), was higher than that for the other fibrotic scores (APRI, NAFLD fibrosis score, FIB-4 index, BARD score, NIKEI) in the construct group. CONCLUSIONS: This simple scoring system accurately predicts fibrotic stage and discriminates patients with advanced fibrosis of NASH.…”
Publicado 2015
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1051“…After CBD clearance was confirmed using the choledochoscope, the choledochotomy was closed with the bard absorbable suture material known as V-loc. RESULTS: The diameter of the CBD ranged from 8 to 30 mm, and the mean size of the stones was 11.6 ± 8.4 mm. …”
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1052por Domagala, Pawel, Jakubowska, Anna, Jaworska-Bieniek, Katarzyna, Kaczmarek, Katarzyna, Durda, Katarzyna, Kurlapska, Agnieszka, Cybulski, Cezary, Lubinski, Jan“…METHODS: Genetic testing was performed for 36 common germline mutations in genes engaged in the repair of DNA by homologous recombination, i.e., BRCA1, BRCA2, CHEK2, NBN, ATM, PALB2, BARD1, and RAD51D, in 202 consecutive patients with triple-negative breast cancers and hereditary non-triple-negative breast cancers. …”
Publicado 2015
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1053por Culligan, Patrick J., Gurshumov, Emil, Lewis, Christa, Priestley, Jennifer L., Komar, Jodie, Shah, Nihar, Salamon, Charbel G.“…All surgeries were performed with a pre-configured monofilament type 1 polypropylene Y-mesh (Alyte©, C.R. Bard, Covington, GA, USA). Cure rates at 12 months were calculated using two separate definitions: (1) “clinical cure”: no POP-Q points > 0, point C ≤ −5, no prolapse symptoms on the PFDI-20, and no reoperations for prolapse and (2) “objective anatomic cure”: POP-Q stage 0 or 1, point C of ≤ −5, and no reoperations for prolapse. …”
Publicado 2013
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1054“…As ovarian cancers frequently respond to DNA-damaging agents, we assessed the clinicopathological significance of key double-strand DNA break (DSB) repair genes, including BRCA1, BRCA2, BARD1, ATM, RAD51 and NBS1 in EOC cell lines and paraffin-embedded tissue sections from 140 EOC patients treated with cytoreductive surgery, followed by platinum-based chemotherapy. …”
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1055por Lasorsa, Vito Alessandro, Formicola, Daniela, Pignataro, Piero, Cimmino, Flora, Calabrese, Francesco Maria, Mora, Jaume, Esposito, Maria Rosaria, Pantile, Marcella, Zanon, Carlo, De Mariano, Marilena, Longo, Luca, Hogarty, Michael D., de Torres, Carmen, Tonini, Gian Paolo, Iolascon, Achille, Capasso, Mario“…Focal adhesion and regulation of actin cytoskeleton pathways, were frequently disrupted (14.1% of cases) thus suggesting potential novel therapeutic strategies to prevent disease progression. Notably BARD1, CHEK2 and AXIN2 were enriched in rare, potentially pathogenic, germline variants. …”
Publicado 2016
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1056“…Other members of this new family of products include MonoMax Suture (Aesculap AG, Tuttlingen, Germany) for soft tissue approximation, BioFiber Scaffold (Tornier, Inc., Edina, MN) for tendon repair, and Phasix Mesh (C.R. Bard, Inc., Murray Hill, NJ) for hernia repair. Each of these fully resorbable products provides prolonged strength retention, typically 50% to 70% strength retention at 12 weeks, and facilitates remodeling in vivo to provide a strong, lasting repair. …”
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1057por Lykiardopoulos, Byron, Hagström, Hannes, Fredrikson, Mats, Ignatova, Simone, Stål, Per, Hultcrantz, Rolf, Ekstedt, Mattias, Kechagias, Stergios“…The following fibrosis algorithms were calculated: NAFLD fibrosis score, BARD, NIKEI, NASH-CRN regression score, APRI, FIB-4, King´s score, GUCI, Lok index, Forns score, and ELF. …”
Publicado 2016
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1058por Feliubadaló, Lídia, Tonda, Raúl, Gausachs, Mireia, Trotta, Jean-Rémi, Castellanos, Elisabeth, López-Doriga, Adriana, Teulé, Àlex, Tornero, Eva, del Valle, Jesús, Gel, Bernat, Gut, Marta, Pineda, Marta, González, Sara, Menéndez, Mireia, Navarro, Matilde, Capellá, Gabriel, Gut, Ivo, Serra, Eduard, Brunet, Joan, Beltran, Sergi, Lázaro, Conxi“…In the discovery set, 240 unique non-silent coding and canonic splice-site variants were identified in the panel genes, 7 of them putatively pathogenic (in ATM, BARD1, CHEK2, ERCC3, FANCL, FANCM, MSH2). The three approaches identified a similar number of variants in the shared genes. …”
Publicado 2017
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1059“…For example, several sex-ratio genes were found to interact with brc-1 and brd-1, the orthologs of the human breast cancer genes BRCA1 and BARD1, respectively. We confirmed the brc-1 interactions with the following genes in DNA damage response: C34F6.1, him-3 (ortholog of HORMAD1, HORMAD2), sdc-1, and set-2 (ortholog of SETD1A, SETD1B, KMT2C, KMT2D), validating the effectiveness of our method in detecting genetic interactions. …”
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1060por Tkalčić, Lovro, Budiselić, Berislav, Kovačević, Miljenko, Knežević, Siniša, Kovačić, Slavica, Miletić, Damir, Tomulić, Vjekoslav, Kuhelj, Dimitrij“…CASE REPORT: Self-expandable, covered stent (Bard, Fluency(®)) was implanted using a single transfemoral approach. …”
Publicado 2017
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