RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma

por Lambing, Silke, Tan, Yu Pan, Vasileiadou, Paraskevi, Holdenrieder, Stefan, Müller, Patrick, Hagen, Christian, Garbe, Stephan, Behrendt, Rayk, Schlee, Martin, van den Boorn, Jasper G, Bartok, Eva, Renn, Marcel, Hartmann, Gunther
Publicado 2023

Distinguishing the Impacts of Inadequate Prey and Vessel Traffic on an Endangered Killer Whale (Orcinus orca) Population

por Ayres, Katherine L., Booth, Rebecca K., Hempelmann, Jennifer A., Koski, Kari L., Emmons, Candice K., Baird, Robin W., Balcomb-Bartok, Kelley, Hanson, M. Bradley, Ford, Michael J., Wasser, Samuel K.
Publicado 2012

Efficacy and safety of filgotinib in methotrexate-naive patients with rheumatoid arthritis with poor prognostic factors: post hoc analysis of FINCH 3

por Aletaha, Daniel, Westhovens, René, Gaujoux-Viala, Cecile, Adami, Giovanni, Matsumoto, Alan, Bird, Paul, Messina, Osvaldo Daniel, Buch, Maya H, Bartok, Beatrix, Yin, Zhaoyu, Guo, Ying, Hendrikx, Thijs, Burmester, Gerd R
Publicado 2021

Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years

por Winthrop, Kevin L, Tanaka, Yoshiya, Takeuchi, Tsutomu, Kivitz, Alan, Matzkies, Franziska, Genovese, Mark C, Jiang, Deyuan, Chen, Kun, Bartok, Beatrix, Jahreis, Angelika, Besuyen, Robin, Burmester, Gerd R, Gottenberg, Jacques-Eric
Publicado 2022

Therapeutic drug monitoring and TB treatment outcomes in patients with diabetes mellitus

por Alkabab, Y., Warkentin, J., Cummins, J., Katz, B., Denison, B. M., Bartok, A., Khalil, A., Young, L. R., Timme, E., Peloquin, C. A., Ashkin, D., Houpt, E. R., Heysell, S. K.
Publicado 2023

IP(3) receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

por Bartok, Adam, Weaver, David, Golenár, Tünde, Nichtova, Zuzana, Katona, Máté, Bánsághi, Száva, Alzayady, Kamil J., Thomas, V. Kaye, Ando, Hideaki, Mikoshiba, Katsuhiko, Joseph, Suresh K., Yule, David I., Csordás, György, Hajnóczky, György
Publicado 2019

Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency

por Jütte, Bianca B., Krollmann, Calvin, Cieslak, Kevin, Koerber, Ruth-Miriam, Boor, Peter, Graef, Claus M., Bartok, Eva, Wagner, Mirko, Carell, Thomas, Landsberg, Jennifer, Aymans, Pia, Wenzel, Jörg, Brossart, Peter, Teichmann, Lino L.
Publicado 2021

Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

por Coch, Christoph, Hommertgen, Benjamin, Zillinger, Thomas, Daßler-Plenker, Juliane, Putschli, Bastian, Nastaly, Maximilian, Kümmerer, Beate M., Scheunemann, Johanna F., Schumak, Beatrix, Specht, Sabine, Schlee, Martin, Barchet, Winfried, Hoerauf, Achim, Bartok, Eva, Hartmann, Gunther
Publicado 2019

The impact of climate change on photovoltaic power generation in Europe

por Jerez, Sonia, Tobin, Isabelle, Vautard, Robert, Montávez, Juan Pedro, López-Romero, Jose María, Thais, Françoise, Bartok, Blanka, Christensen, Ole Bøssing, Colette, Augustin, Déqué, Michel, Nikulin, Grigory, Kotlarski, Sven, van Meijgaard, Erik, Teichmann, Claas, Wild, Martin
Publicado 2015

Efficacy and Safety of Filgotinib in Patients with High Risk of Poor Prognosis Who Showed Inadequate Response to MTX: A Post Hoc Analysis of the FINCH 1 Study

por Combe, Bernard G., Tanaka, Yoshiya, Buch, Maya H., Nash, Peter, Burmester, Gerd R., Kivitz, Alan J., Bartok, Beatrix, Pechonkina, Alena, Xia, Katrina, Emoto, Kahaku, Kano, Shungo, Hendrikx, Thijs K., Landewé, Robert B. M., Aletaha, Daniel
Publicado 2022

Correction: Efficacy and Safety of Filgotinib in Patients with High Risk of Poor Prognosis Who Showed Inadequate Response to MTX: A Post Hoc Analysis of the FINCH 1 Study

por Combe, Bernard G., Tanaka, Yoshiya, Buch, Maya H., Nash, Peter, Burmester, Gerd R., Kivitz, Alan J., Bartok, Beatrix, Pechonkina, Alena, Xia, Katrina, Emoto, Kahaku, Kano, Shungo, Hendrikx, Thijs K., Landewé, Robert B. M., Aletaha, Daniel
Publicado 2023

Translation of CircRNAs

por Pamudurti, Nagarjuna Reddy, Bartok, Osnat, Jens, Marvin, Ashwal-Fluss, Reut, Stottmeister, Christin, Ruhe, Larissa, Hanan, Mor, Wyler, Emanuel, Perez-Hernandez, Daniel, Ramberger, Evelyn, Shenzis, Shlomo, Samson, Moshe, Dittmar, Gunnar, Landthaler, Markus, Chekulaeva, Marina, Rajewsky, Nikolaus, Kadener, Sebastian
Publicado 2017

A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA

por de Regt, Ann Kristin, Anand, Kanchan, Ciupka, Katrin, Bender, Felix, Gatterdam, Karl, Putschli, Bastian, Fusshöller, David, Hilbig, Daniel, Kirchhoff, Alexander, Hunkler, Charlotte, Wolter, Steven, Grünewald, Agathe, Wallerath, Christina, Schuberth-Wagner, Christine, Ludwig, Janos, Paeschke, Katrin, Bartok, Eva, Hagelueken, Gregor, Hartmann, Gunther, Zillinger, Thomas, Geyer, Matthias, Schlee, Martin
Publicado 2023

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N(1)-2′O-Methylated Self RNA

por Schuberth-Wagner, Christine, Ludwig, Janos, Bruder, Ann Kristin, Herzner, Anna-Maria, Zillinger, Thomas, Goldeck, Marion, Schmidt, Tobias, Schmid-Burgk, Jonathan L., Kerber, Romy, Wolter, Steven, Stümpel, Jan-Philip, Roth, Andreas, Bartok, Eva, Drosten, Christian, Coch, Christoph, Hornung, Veit, Barchet, Winfried, Kümmerer, Beate M., Hartmann, Gunther, Schlee, Martin
Publicado 2015

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to metho...

por Westhovens, René, Rigby, William F C, van der Heijde, Désirée, Ching, Daniel W T, Stohl, William, Kay, Jonathan, Chopra, Arvind, Bartok, Beatrix, Matzkies, Franziska, Yin, Zhaoyu, Guo, Ying, Tasset, Chantal, Sundy, John S, Jahreis, Angelika, Mozaffarian, Neelufar, Messina, Osvaldo Daniel, Landewé, Robert BM, Atsumi, Tatsuya, Burmester, Gerd R
Publicado 2021

Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus

por Steiner, Annemarie, Reygaerts, Thomas, Pontillo, Alessandra, Ceccherini, Isabella, Moecking, Jonas, Moghaddas, Fiona, Davidson, Sophia, Caroli, Francesco, Grossi, Alice, Castro, Fabio Fernandes Morato, Kalil, Jorge, Gohr, Florian N., Schmidt, Florian I., Bartok, Eva, Zillinger, Thomas, Hartmann, Gunther, Geyer, Matthias, Gattorno, Marco, Mendonça, Leonardo Oliveira, Masters, Seth L.
Publicado 2021

Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial

por Combe, Bernard, Kivitz, Alan, Tanaka, Yoshiya, van der Heijde, Désirée, Simon, J Abraham, Baraf, Herbert S B, Kumar, Uma, Matzkies, Franziska, Bartok, Beatrix, Ye, Lei, Guo, Ying, Tasset, Chantal, Sundy, John S, Jahreis, Angelika, Genovese, Mark C, Mozaffarian, Neelufar, Landewé, Robert B M, Bae, Sang-Cheol, Keystone, Edward C, Nash, Peter
Publicado 2021

Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany

por Streeck, Hendrik, Schulte, Bianca, Kümmerer, Beate M., Richter, Enrico, Höller, Tobias, Fuhrmann, Christine, Bartok, Eva, Dolscheid-Pommerich, Ramona, Berger, Moritz, Wessendorf, Lukas, Eschbach-Bludau, Monika, Kellings, Angelika, Schwaiger, Astrid, Coenen, Martin, Hoffmann, Per, Stoffel-Wagner, Birgit, Nöthen, Markus M., Eis-Hübinger, Anna M., Exner, Martin, Schmithausen, Ricarda Maria, Schmid, Matthias, Hartmann, Gunther
Publicado 2020

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

por Kettwig, Matthias, Ternka, Katharina, Wendland, Kristin, Krüger, Dennis Manfred, Zampar, Silvia, Schob, Charlotte, Franz, Jonas, Aich, Abhishek, Winkler, Anne, Sakib, M. Sadman, Kaurani, Lalit, Epple, Robert, Werner, Hauke B., Hakroush, Samy, Kitz, Julia, Prinz, Marco, Bartok, Eva, Hartmann, Gunther, Schröder, Simone, Rehling, Peter, Henneke, Marco, Boretius, Susann, Alia, A., Wirths, Oliver, Fischer, Andre, Stadelmann, Christine, Nessler, Stefan, Gärtner, Jutta
Publicado 2021