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  1. 1101
    “…Finally, the bone regeneration potential of PLGA nanoparticles in three-walled defects in beagle dogs was investigated. The results indicated that PLGA-lovastatin-chitosan-tetracycline nanoparticles showed good biocompatibility, antibacterial activity, and increased alkaline phosphatase activity. …”
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    Controlled-release of tetracycline and lovastatin by poly(d,l-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs
  2. 1102
    “…In models of stored blood transfusion and hemoglobin (Hb) exposure in guinea pigs and beagle dogs we found that hemoglobinuria led to intrarenal conversion of ferrous Hb(Fe(2+)) to ferric Hb(Fe(3+)), accumulation of free heme and Hb-cross-linking products, enhanced 4-hydroxynonenal reactivity in renal tissue, and acute tubule injury. …”
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    Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response
  3. 1103
    “…Pharmacokinetics of this 30-mg mianserin preparation were evaluated in three beagle dogs and three healthy adult males, in line with ethics committee approval. …”
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    The pharmacokinetics of mianserin suppositories for rectal administration in dogs and healthy volunteers: a pilot study
  4. 1104
    “…We report here that three immunizations with either the recombinant ES LaPSA-38S (rPSA) or its carboxy terminal part LaPSA-12S (Cter-rPSA), combined with QA-21 as adjuvant, confer high levels of protection in naive L. infantum-infected Beagle dogs, as checked by bone marrow parasite absence in respectively 78.8% and 80% of vaccinated dogs at 6 months post-challenge. …”
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    Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs
  5. 1105
    “…The cell scaffold composites were examined by scanning electron microscopy (SEM) and implanted into beagles with articular cartilage defects. The expression of osteogenic markers, alkaline phosphatase and bone γ-carboxyglutamate protein (BGLAP) were assessed using polymerase chain reaction after 3 months. …”
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    Use of a biological reactor and platelet-rich plasma for the construction of tissue-engineered bone to repair articular cartilage defects
  6. 1106
    “…We evaluated whether periodontal wound healing is promoted by application of collagen hydrogel scaffold in combination with FGF2 in furcation defects in beagle dogs. METHODS: Collagen hydrogel was fabricated from bovine type I collagen with an ascorbate-copper ion cross-linking system. …”
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    Collagen Hydrogel Scaffold and Fibroblast Growth Factor-2 Accelerate Periodontal Healing of Class II Furcation Defects in Dog
  7. 1107
    por Cohen, Joel I.
    Publicado 2016
    “…To do this, themes from studying the “Nature of Science” are used to examine how Darwin’s “way of knowing” advanced before and after his voyage upon HMS Beagle. Five themes from the “Nature of Science” were selected to illustrate Darwin’s struggles and triumph: creating scientific knowledge is a human endeavor, such knowledge can explain an order and consistency in natural systems, knowledge comes from a scientist’s way of knowing, is open to revision, and based on empirical evidence. …”
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    Exploring the nature of science through courage and purpose: a case study of Charles Darwin’s way of knowing
  8. 1108
    “…The last two beagles in both groups were sacrificed at the end of 5(th) month. …”
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    Paclitaxel Drug-eluting Tracheal Stent Could Reduce Granulation Tissue Formation in a Canine Model
  9. 1109
    “…Blood and saliva samples were collected from 10 research Beagle dogs twice daily for 5 consecutive days, and from 33 privately-owned blood donor dogs in association with 50 different blood donation occasions. …”
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    Catestatin and vasostatin concentrations in healthy dogs
  10. 1110
    “…METHODS: Nine dog breeds were recruited in this study (Beagle, Chihuahua, Cocker Spaniel, Dachshund, Golden Retriever, Greyhound, German Shepherd, Labrador Retriever and Maltese: 7–12 dogs per breed). …”
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    Ultra high performance liquid chromatography–high resolution mass spectrometry plasma lipidomics can distinguish between canine breeds despite uncontrolled environmental variability and non-standardized diets
  11. 1111
    “…METHODS: The mandibular 4th premolar teeth in 5 adult beagle dogs served as experimental units. Periodontal and endodontic lesions were induced in 1 premolar site in each animal using wire ligatures and pulpal exposure over 3 months (diseased sites). …”
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    Periodontal and endodontic pathology delays extraction socket healing in a canine model
  12. 1112
    “…In larger mammals, this difference in pharmacokinetics allowed for 28 day continuous dosing of G1T38 in beagle dogs without producing severe neutropenia. …”
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    Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors
  13. 1113
    “…Canine MSCs overexpressing HO-1 were generated by using a lentivirus packaging protocol. Eight beagle dogs with experimentally-induced SCI were divided into GFP-labeled MSC (MSC-GFP) and HO-1-overexpressing MSC (MSC-HO-1) groups. …”
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    Effect of canine mesenchymal stromal cells overexpressing heme oxygenase-1 in spinal cord injury
  14. 1114
    “…To investigate mechanism of immunoallergic hepatitis beagle dogs were given 1 or 3 mg/kg/day (HD) oral diclofenac for 28 days. …”
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    The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury
  15. 1115
    “…Using four popular imputation programs (Beagle, FImpute, Impute2, Minimac) and various compositions of reference panels, the accuracy of the imputed sequence variant genotypes was high and differences between the programs and scenarios were small. …”
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    Highly accurate sequence imputation enables precise QTL mapping in Brown Swiss cattle
  16. 1116
    “…ANIMALS: Four groups of 8 6‐ to 8‐month‐old male Beagle dogs were used. METHODS: Thirty‐two healthy seronegative dogs were inoculated experimentally with serovars Canicola, Grippotyphosa, Icterohaemorrhagiae, and Pomona (8 dogs/serovar). …”
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    Evaluation of 3 Serological Tests for Early Detection Of Leptospira‐specific Antibodies in Experimentally Infected Dogs
  17. 1117
    “…Material and Methods: The bilateral premolars P2, P3, P4 and the first mandibular molar were extracted atraumatically from six Beagle dogs. The clean, dry teeth were ground immediately using the Smart Dentin Grinder. …”
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    The Use of Tooth Particles as a Biomaterial in Post-Extraction Sockets. Experimental Study in Dogs
  18. 1118
    “…Animals: Ten healthy beagle dogs. Procedures: Dogs were anesthetized and positioned in dorsal recumbency in a 3.0 Tesla MR scanner. …”
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    Assessment of Myocardial Perfusion at Rest and During Stress Using Dynamic First-Pass Contrast-Enhanced Magnetic Resonance Imaging in Healthy Dogs
  19. 1119
    “…The present study aimed to evaluate influences of sevoflurane anesthesia on the distribution of robenacoxib in dogs. Ten healthy beagle dogs (1 to 11 years old, 9.3 to 14.3 kg body weight, 6 males and 4 females) were subcutaneously administered robenacoxib (2 mg/kg) under conscious condition or sevoflurane anesthesia inhaled a 1.3-fold predetermined individual minimum alveolar concentration of sevoflurane at a 28-day interval. …”
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    Influence of sevoflurane anesthesia with mechanical ventilation and fluid-therapy on distribution of subcutaneously administered robenacoxib in dogs
  20. 1120
    por Rollin, Bernard E.
    Publicado 2018
    “…If one considers the most popular dog breeds in the United States, the top 10 include the Labrador Retriever, German Shepherd, Golden Retriever, French Bulldog, Beagle, Poodle, Rottweiler, Yorkshire Terrier, and German Shorthaired Pointer. …”
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    “We Always Hurt the Things We Love”—Unnoticed Abuse of Companion Animals
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