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  1. 1361
    “…METHODS: Imputation validation sets were composed of random purebred or crossbred Merinos, while imputation reference sets were of variable sizes and included random purebred or crossbred Merinos or a group of animals that were selected based on high genetic relatedness to animals in the validation set. The Beagle software program was used for imputation and accuracy of imputation was assessed based on the Pearson correlation coefficient between observed and imputed genotypes. …”
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    Accuracy of genotype imputation based on random and selected reference sets in purebred and crossbred sheep populations and its effect on accuracy of genomic prediction
  2. 1362
    “…Genotypes for the high-density 770 K SNP panel were imputed using Beagle software. Various Bayesian regression methods were used to predict single QTL or a trait influenced by 42 such QTL. …”
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    Accuracy of prediction of simulated polygenic phenotypes and their underlying quantitative trait loci genotypes using real or imputed whole-genome markers in cattle
  3. 1363
    “…FIMPUTE V2.2 outperformed BEAGLE 3.3.2 across all imputation scenarios. CONCLUSIONS: Imputation accuracy in sheep breeds can be improved by following a set of recommendations on SNP panels, software, strategies of imputation (one- or two-step imputation), and choice of the animals to be genotyped using both high- and low-density SNP panels. …”
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    Assessing accuracy of imputation using different SNP panel densities in a multi-breed sheep population
  4. 1364
    “…An analysis of imputation accuracy of missing genotypic data was conducted using the software Beagle, showing that two of the eleven populations were highly sensitive to increasing levels of missing data. …”
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    Genome-enabled predictions for fruit weight and quality from repeated records in European peach progenies
  5. 1365
    “…A four period cross-over blinded study was conducted in eight healthy beagle dogs of both genders. Dogs were administered 18 mg/m(2) cisplatin intravenously, followed 45 min later by a 15 min infusion of either placebo (saline) or antiemetic treatment with ondansetron (0.5 mg/kg; 5-HT(3) antagonist), maropitant (1 mg/kg; NK(1) antagonist) or metoclopramide (0.5 mg/kg; D(2) antagonist). …”
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    Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study
  6. 1366
    “…The safety of lotilaner flavoured chewable tablets was investigated in a randomized, blinded, parallel-group design study in healthy Beagle puppies starting at 8 weeks of age. Lotilaner was administered orally once a month over 8 months at one, three and five times the upper level of the recommended dose range (of 20 to 43 mg/kg). …”
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    Safety evaluation of lotilaner in dogs after oral administration as flavoured chewable tablets (Credelio™)
  7. 1367
    “…METHODS: In each of two studies, 16 Beagle dogs, at least 6 months old, were ranked and blocked by tick counts from infestations placed approximately 1 week before treatment. …”
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    Laboratory evaluations of the immediate and sustained effectiveness of lotilaner (Credelio™) against three common species of ticks affecting dogs in Europe
  8. 1368
    “…METHODS: Twelve purpose-bred Beagle dogs (six males and six females) were selected and randomly allocated to two groups, untreated controls and PH6-treated dogs in groups of six each. …”
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    Evaluation of the efficacy of ProHeart(®) 6 (moxidectin) against a resistant isolate of Dirofilaria immitis (JYD-34) in dogs
  9. 1369
    “…BACKGROUND: This study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, DPP, Vectra® 3D, Ceva Animal Health) combined with a macrocyclic lactone (milbemycin oxime, MBO, Interceptor®, Virbac) on transmission of heartworm L3 from mosquitoes to dogs and subsequent development of worms in treated dogs exposed to infected mosquitoes. METHODS: Thirty-two beagle dogs were allocated to four groups of eight: Group 1, untreated controls; Group 2, treated topically with DPP on Day 0; Group 3, treated orally with MBO on Day 51; and Group 4, treated with DPP on Day 0 and MBO on Day 51. …”
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    Shifting the paradigm in Dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach
  10. 1370
    “…METHODS: One of two isolates (JYD-34 or Big Head™) were used to infect naïve laboratory beagle dogs. Serum was collected from dogs weekly and divided into two aliquots, heated and unheated. …”
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    Evaluation of Dirofilaria immitis antigen detection comparing heated and unheated serum in dogs with experimental heartworm infections
  11. 1371
    “…BovineHD genotypes for all bulls were imputed to WGS using Beagle4 and Minimac2. Genomic prediction across the three populations was performed with ASReml4, with each population used as single reference and as single validation sets. …”
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    Utility of whole-genome sequence data for across-breed genomic prediction
  12. 1372
    “…RESULTS: Two groups of beagle dogs (n = 9) were administered either: (1) a nonadjuvanted/monovalent, recombinant OspA vaccine (Recombitek® Lyme) or (2) an adjuvanted, recombinant OspA /OspC chimeric fusion vaccine (Vanguard® crLyme). …”
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    Characterization of recombinant OspA in two different Borrelia vaccines with respect to immunological response and its relationship to functional parameters
  13. 1373
    “…METHODS: Direct feeding bioassays were performed on 10 beagle dogs that had been randomly assigned to two groups: one with five dogs orally treated with Bravecto® (fluralaner) and other five as a control. …”
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    A randomized, blinded, controlled trial to assess sand fly mortality of fluralaner administered orally in dogs
  14. 1374
    “…RESULTS: Using Illumina Bovine 50 K (54,609 SNPs) and GeneSeek HD (138,893 SNPs) chips, two analytical approaches were performed, GRAMMAR-GC and ROADTRIPS in 937 Chinese Holstein cows, among which individuals genotyped by the 50 K chip were imputed to HD SNPs with Beagle software. Consequently, 15 and 11 significant SNPs (P < 5 × 10(− 5)) were identified with GRAMMAR-GC and ROADTDRIPS, respectively. …”
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    Genome-wide association study of Mycobacterium avium subspecies Paratuberculosis infection in Chinese Holstein
  15. 1375
    “…French and Romanians (n = 465) were genotyped for SNPs (Affymetrix) and enriched by imputation (BEAGLE 4.1) at 1000 genome project density. Initial association hits detected by sliding window were refined (HAPLOVIEW 3.1 and PHASE 2.1) and correlated to homeostasis model assessment (HOMA(IR)) index, in vivo insulin sensitivity (S(I)) and BCAA plasma levels (ANOVA). …”
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    Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation
  16. 1376
    “…Genotype phasing and imputation using the Beagle software improved the quality of the sequence variant genotypes for all the tools evaluated, particularly for animals that were sequenced at low coverage. …”
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    Accurate sequence variant genotyping in cattle using variation-aware genome graphs
  17. 1377
    “…In addition, animals’ weight and breed influenced dogs’ intake of the most preferred diets, where heaviest dogs presented lower intakes as did the Beagle breed in relation with both Boxer and Labrador Retrievers. …”
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    Food Preferences in Dogs: Effect of Dietary Composition and Intrinsic Variables on Diet Selection
  18. 1378
    “…BACKGROUND: The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. …”
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    Safety of an extended-release injectable moxidectin suspension formulation (ProHeart(®) 12) in dogs
  19. 1379
    “…BACKGROUND: The objective of this study was to assess the efficacy of intra-articular injections of hyaluronic acid (HA) and a novel, on-site conjugate of HA with autologous fibrinogen in platelet-rich plasma (HA-PRP) in a canine model of osteoarthritis (OA) METHODS: Twelve beagle dogs underwent a unilateral resection of the cranial cruciate ligament (CrCL) of the stifle joint. …”
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    A placebo-controlled study comparing the efficacy of intra-articular injections of hyaluronic acid and a novel hyaluronic acid-platelet-rich plasma conjugate in a canine model of osteoarthritis
  20. 1380
    “…Safety of EO1001 was evaluated by repeat-dosing studies in SD rats and beagle dogs. Toxicities typical of the ErbB inhibitor class, including gastro-intestinal effects, weight loss and decreased activity were observed at higher dose groups in both species. …”
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    THER-01. PRECLINICAL DEVELOPMENT OF EO1001, A NOVEL IRREVERSIBLE BRAIN PENETRATING PAN-ErbB INHIBITOR
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