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1021“…METHODS: 12 adult, female, Long-Evans rats, 6 sham and 6 mild-moderate T8 iSCI, were tested 4 weeks following injury. The Basso Beattie Bresnahan locomotor score was used to verify injury severity. …”
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1022por Cheng, Chu-Hsun, Lin, Chi-Te, Lee, Meng-Jen, Tsai, May-Jywan, Huang, Wen-Hung, Huang, Ming-Chao, Lin, Yi-Lo, Chen, Ching-Jung, Huang, Wen-Cheng, Cheng, Henrich“…In addition, retrograde Fluoro-Gold (FG) labeling showed that the outgrowing axons could cross the lesion site and reach several brain stem nuclei involved in sensory and motor functions. The Basso, Beattie and Bresnahan (BBB) open field locomotor scores revealed that the ChABC treatment significantly improved functional recovery compared to the control group at eight weeks after treatment. …”
Publicado 2015
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1023por Kanchiku, Tsukasa, Suzuki, Hidenori, Imajo, Yasuaki, Yoshida, Yuichiro, Moriya, Atsushi, Suetomi, Yutaka, Nishida, Norihiro, Takahashi, Youhei, Taguchi, Toshihiko“…Motor function was evaluated using Basso, Beattie, Bresnahan (BBB) scores and three-dimensional (3D) gait analysis. …”
Publicado 2015
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1024por Hosier, Hillary, Peterson, David, Tsymbalyuk, Orest, Keledjian, Kaspar, Smith, Bradley R., Ivanova, Svetlana, Gerzanich, Volodymyr, Popovich, Phillip G., Simard, J. Marc“…On open-field locomotor scores (modified Basso, Beattie, and Bresnahan scores), hypothermia- and glibenclamide-treated animals were largely indistinguishable throughout the study, whereas riluzole-treated rats underperformed for the first two weeks; during the last four weeks, scores for the three treatments were similar, and significantly different from controls. …”
Publicado 2015
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1025“…A weight-drop model was performed at T9. The Basso-Beattie-Bresnahan (BBB) score was used to evaluate neurological function. …”
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1026por Miranpuri, Gurwattan S., Schomberg, Dominic T., Alrfaei, Bahauddeen, King, Kevin C., Rynearson, Bryan, Wesley, Vishwas S., Khan, Nayab, Obiakor, Kristen, Wesley, Umadevi V., Resnick, Daniel K.“…Locomotor functional recovery of injured rats was measured on post cSCI day 1, and weekly thereafter for 6 weeks using Basso, Beattie and Bresnahan scores. Thermal hyperalgesia (TH) testing was performed on days 21, 28, 35 and 42 post cSCI. …”
Publicado 2016
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1027por Gao, Kai, Shen, Zhaoliang, Yuan, Yajiang, Han, Donghe, Song, Changwei, Guo, Yue, Mei, Xifan“…Furthermore, the Basso, Beattie, and Bresnahan scores indicated that Simv treatment significantly improved the locomotor functions of rats after SCI. …”
Publicado 2016
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1028“…The recovery of neural function was determined using the Basso, Beattie, and Bresnahan test. RESULTS: NGF therapy using US-mediated NGF/PLGA NBs destruction significantly increased NGF expression, attenuated histological injury, decreased neuron loss, inhibited neuronal apoptosis in injured spinal cords, and increased BBB scores in rats with SCI. …”
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1029por Chen, Hailong, Li, Junjie, Liang, Shuhan, Lin, Bin, Peng, Qi, Zhao, Peng, Cui, Jiawei, Rao, Yaojian“…The control and treatment groups were subjected to spinal cord hemisection and motor activity was evaluated using the Basso, Beattie and Bresnahan (BBB) scoring system. Expression of HIF-1α and VEGF in each injured spinal cord section was assessed using immunohistochemistry. …”
Publicado 2017
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1030“…Moreover, in a separate set of experiments, we clearly demonstrated that HSYA treatment significantly ameliorated recovery of limb function (as evaluated by Basso, Beattie, and Bresnahan behavioral recovery scores). …”
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1031por Wang, Hongyu, Mei, Xifan, Cao, Yang, Liu, Chang, Zhao, Ziming, Guo, Zhanpeng, Bi, Yunlong, Shen, Zhaoliang, Yuan, Yajiang, Guo, Yue, Song, Cangwei, Bai, Liangjie, Wang, Yansong, Yu, Deshui“…RAGE blockade does not improve neurobehavior Basso, Beattie and Bresnahan (BBB) scores; however, it damaged survival of ventral neurons via Nissl staining. …”
Publicado 2017
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1032“…Finally, SHED and SHED-Ex were locally injected into TBI rat models. Basso, Beattie, and Bresnahan (BBB) scores were chosen to evaluate the motor functional recovery. …”
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1033por Zhang, Ya-Dong, Zhu, Zhong-Sheng, Zhang, Dong, Zhang, Zhen, Ma, Bin, Zhao, Shi-Chang, Xue, Feng“…A total of 126 rats were divided into normal, sham, SCI, negative control (NC), PTC1-RNAi, PTC2-RNAi and PTC1/PTC2-RNAi groups. The Basso, Beattie and Bresnahan (BBB) scale was employed to assess hind limb motor function. …”
Publicado 2017
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1034por He, Yongxiong, Lv, Bokang, Huan, Yanqiang, Liu, Bin, Li, Yutang, Jia, Lizhou, Qu, Chenhui, Wang, Dongsheng, Yu, Hai, Yuan, Hongwei“…The hind limb motor function of the rats was evaluated by Basso, Beattie, Bresnahan (BBB) scoring system. Quantitative real-time PCR (qRT-PCR) and Western blot were used to detect the expression of miR-146a-5p, GPR17, inducible nitric oxide synthase (iNOS), interleukin 1β (IL-1β), and tumor necrosis factor α (TNF-α). …”
Publicado 2018
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1035por Ruzicka, Jiri, Urdzikova, Lucia Machova, Svobodova, Barbora, Amin, Anubhav G., Karova, Kristyna, Dubisova, Jana, Zaviskova, Kristyna, Kubinova, Sarka, Schmidt, Meic, Jhanwar-Uniyal, Meena, Jendelova, Pavla“…Rats were evaluated using behavioral tests (the Basso, Beattie, and Bresnahan (BBB) open-field locomotor test, flat beam test). …”
Publicado 2018
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1036por Joo, Min Cheol, Jang, Chul Hwan, Park, Jong Tae, Choi, Seung Won, Ro, Seungil, Kim, Min Seob, Lee, Moon Young“…On days 2 and 7 post SCI, the Touch-Test Sensory Evaluators and the Basso-Beattie-Bresnahan locomotor scale were used to evaluate rat sensory and motor function. …”
Publicado 2018
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1037“…The motor behavioral function of rats was improved following treatment with MTX according to Basso, Beattie and Bresnahan scoring (P<0.05). Terminal deoxynucleotidyl-transferase-mediated dUTP nick end staining indicated that there were no apoptotic cells present in sham rats. …”
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1038“…Biotinylated dextran amine (BDA) was injected at thoracic level 5 to evalute axon regeneration. The Basso, Beattie, and Bresnahan locomotor test, Gridwalk test, and sensory test using von Frey filaments were performed to assess functional recovery. …”
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1039por Yao, Shenglian, Yu, Shukui, Cao, Zheng, Yang, Yongdong, Yu, Xing, Mao, Hai-Quan, Wang, Lu-Ning, Sun, Xiaodan, Zhao, Lingyun, Wang, Xiumei“…Additionally, the abundant blood vessels marked with RECA-1 had reconstructed within the lesion site at 4 weeks after surgery. Basso-Beattie-Bresnahan scoring showed that the locomotor performance of the AFG group recovered much faster than that of blank control group or the random fibrin hydrogel (RFG) group from 2 weeks after surgery. …”
Publicado 2018
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1040por Khan, Imdad Ullah, Yoon, Yongseok, Kim, Ahyoung, Jo, Kwang Rae, Choi, Kyeung Uk, Jung, Taeseong, Kim, Namyul, Son, YeonSung, Kim, Wan Hee, Kweon, Oh-Kyeong“…The groups were compared in terms of improvement in canine Basso, Beattie, and Bresnahan (cBBB) score during 8 weeks of experimentation. …”
Publicado 2018
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