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1081por Jia, Yijia, Lu, Tingsheng, Chen, Qiling, Pu, Xingwei, Ji, Linsong, Yang, Jianwen, Luo, Chunshan“…Shh expression in spinal cord tissues in these animals was then assessed via immunohistochemical staining, while Basso-Beattie-Bresnahan (BBB) scores were utilized to measure high limb motor function. …”
Publicado 2021
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1082por Wang, Fang, Li, Jiaxi, Zhao, Yingjie, Guo, Dong, Liu, Dongfan, Chang, Su'e, Qiao, Hao, Li, Jie, Yang, Yubing, Zhang, Chengyi, Wang, Rui, Li, Fengtao, Wang, Dong, Li, Haopeng, He, Xijing“…In the present study, a T10 weight-dropping SCI model was established and miRNA profiling was used to detect miRNA expression profiles post-SCI. Basso-Beattie-Bresnahan scores and inclined plane test, hematoxylin and eosin (HE) and Nissl staining, immunohistochemistry and immunofluorescence, western blotting, cell viability, and Annexin V/7-aminoactinomycin D (7-AAD) assays were used to evaluate locomotor activity, histological changes in the injured spinal cords, neuronal ferroptosis, ferroptosis suppressor protein 1 (FSP1) expression, and cell death, respectively. …”
Publicado 2022
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1083por Han, Tianyu, Song, Peiwen, Wu, Zuomeng, Xiang, Xia, Liu, Yunlei, Wang, Ying, Fang, Huang, Niu, Yang, Shen, Cailiang“…In addition, immunohistochemistry staining; hematoxylin–eosin staining; and the Basso, Beattie, and Bresnahan (BBB) scores revealed that the early inhibition of TGF-β did not increase neuron regrowth. …”
Publicado 2021
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1084por Yan, Rongbao, Li, Erliang, Yan, Kang, Zhang, Qian, Wen, Yanhua, Zhang, Rui, Wu, Yonghong, Sun, Jin, Dong, Xin, Ma, Qiong, Liao, Bo“…Within 35 days postinjury (dpi), the Basso, Beattie, and Bresnahan locomotor rating scale (BBB) was used to evaluate the hindlimb motor function of the rats. …”
Publicado 2022
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1085por Hu, Zi-Bing, Chen, Hai-Cong, Wei, Bo, Zhang, Zhong-Min, Wu, Shao-Ke, Sun, Jie-Cong, Xiang, Min“…Rats were divided into four groups: a double-treatment group (receiving both neurogenic-induced hDPSCs and PRP), two single-treatment groups (receiving neurogenic-induced hDPSCs or PRP) and a sham group (receiving normal saline). The Basso, Beattie, Bresnahan Locomotor Rating Scale was subsequently used to evaluate the motor function of the spinal cord. …”
Publicado 2022
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1086“…Comprehensive behavior score and Basso Beattie Bresnahan were used to evaluate the mental state and exercise of rats every day. …”
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1087“…ChABC-treated rats had a Basso, Beattie, and Bresnahan (BBB) motor score of 3.8 at 2 weeks, 7.1 at 3 weeks, and 10.3 at 8 weeks after CST. …”
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1088por Zhang, Ya-yun, Yao, Min, Zhu, Ke, Xue, Rui-rui, Xu, Jin-hai, Cui, Xue-jun, Mo, Wen“…We included studies which examined neurological function by the Basso, Beattie, and Bresnahan (BBB) scale, as well as cavity area and spared area, and determining the molecular-biological analysis of antioxidative effects by malondialdehyde (MDA) levels in spinal cord tissues. …”
Publicado 2022
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1089“…In addition, we measured functional recovery using the Basso, Beattie, Besnahan (BBB) score and we analyzed the relevant mechanisms to explore the similarities between different studies. …”
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1090por Farid, Mariam F., Abouelela, Yara S., Yasin, Noha A. E., Mousa, Mohamed R., Ibrahim, Marwa A., Prince, Abdelbary, Rizk, Hamdy“…PRP was obtained by centrifuging blood on anticoagulant citrate dextrose and activating it with red and green laser diodes. The Basso–Beattie–Bresnahan (BBB) scores were used to assess the motor function recovery on days 1, 3, 7, 14, 20, and 28 following 14 days from EB injection. …”
Publicado 2022
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1091por Sharifi, Atousa, Zandieh, Ali, Behroozi, Zahra, Hamblin, Michael R., Mayahi, Sara, Yousefifard, Mahmoud, Ramezani, Fatemeh“…The standard mean difference of the score of the functional recovery that measured by Basso, Beattie, Bresnahan (BBB) test after SCI was used to analyze the results of the reported studies. …”
Publicado 2022
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1092por Naeimi, Arvin, Zaminy, Arash, Amini, Naser, Balabandi, Raziye, Golipoor, Zoleikha“…Immunohistochemistry(IHC) was used to assess the engraftment and differentiation of ADSCs in the SCI site. Basso, Beattie, and Bresnahan's score was used to evaluate motor function between the six groups. …”
Publicado 2022
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1093por Liu, Guangyang, Zhao, Zhiling, Wang, Herui, Hao, Chunhua, Wang, Weiting, Zhang, Chenliang, Wang, Tiehua, Li, Xin, Xi, Jingjing, Li, Shaoyun, Long, Haomiao, Mi, Yi, Miao, Li, Chen, Yaoyao, Xu, Liqiang, Zheng, Libo, Wang, Hao, Ding, Ning, Zhu, Fengmei, Ge, Qinggang, Liu, Yongjun“…The locomotor function was assessed by Basso Beattie Bresnahan (BBB) rating score, magnetic resonance imaging (MRI), histopathology, and immunofluorescence. …”
Publicado 2022
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1094“…Administration of the MIAT knockdown vector led to the establishment of the SCIRI rat model. Basso, Beattie & Bresnahan locomotor rating scale (BBB) assessment of hind limb motion. …”
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1095por Fu, Xuanhao, Ma, Boyuan, Zhou, Mengmeng, Cheng, Yuelin, Liu, Linyan, Kan, Shunli, Liu, Chengjiang, Zhao, Xinyan, Feng, Sa, Zhu, Haoqiang, Hu, Wei, Jiang, Zehua, Zhu, Rusen“…Results from animal experiments revealed that EPI not only markedly improved Basso, Beattie, and Bresnahan scores in SCI rats, but also significantly improved p-PI3K/PI3K and p-AKT/AKT ratio. …”
Publicado 2023
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1096“…RESULTS: HNSCs-secretome significantly improved locomotor recovery according to Basso, Beattie, Bresnahan (BBB) scores and increased neurogenesis (nestin, BDNF, and GDNF), neuroangiogenesis (VEGF), anti-apoptotic (Bcl-2), anti-inflammatory (IL-10 and TGF-β), but decreased pro-inflammatory (NF-κB, MMP9, TNF-α), F2-Isoprostanes, and spinal cord lesion size. …”
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1097por Tao, Jing-Wei, Fan, Xiao, Zhou, Jing-Ya, Huo, Lu-Yao, Mo, Yan-Jun, Bai, Hui-Zhong, Zhao, Yi, Ren, Jing-Pei, Mu, Xiao-Hong, Xu, Lin“…OBJECTIVE: To investigate the effects of G-CSF on Basso, Beattie, and Bresnahan (BBB) scale score, inclined plane test, electrophysiologic exam, quantitative analysis of TUNEL-positive cells, and quantitative analysis of glial fibrillary acidic protein (GFAP) immunostaining images in animal models of SCI. …”
Publicado 2023
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1098“…METHODS: Male Sprague-Dawley (SD) rats were used to established an in vivo SCI model and were intraperitoneally injected with lentivirus particles encoding a MALAT1 small interfering RNA (siRNA) on day 10 prior to SCI and with 0.2 mg/kg LPS 72 h prior to SCI. Basso, Beattie, and Bresnahan (BBB) scoring; HE staining; and TUNEL assay were used to assess neurological function and pathophysiological changes. …”
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1099por Butler, Max B., Vellaiyappan, Sundar K., Bhatti, Faheem, Syed, Fazal-E-Momin, Rafati Fard, Amir, Teh, Jye Quan, Grodzinski, Ben, Akhbari, Melika, Adeeko, Sylva, Dilworth, Rory, Bhatti, Aniqah, Waheed, Unaiza, Robinson, Sophie, Osunronbi, Temidayo, Walker, Benn, Ottewell, Luke, Suresh, Gayathri, Kuhn, Isla, Davies, Benjamin M., Kotter, Mark R. N., Mowforth, Oliver D.“…The most commonly assessed outcome measures were Basso, Beattie, Bresnahan (BBB) locomotor score (n = 13), and grid walking (n = 7). …”
Publicado 2023
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1100“…Results: The injection of BMSC or BMSC-Exo enhanced locomotor performance reflected by Basso, Beattie & Bresnahan score (p < 0.001), and neuronal viability reflected by NeuN(+) cells (p < 0.01), but attenuated neuronal apoptosis reflected by TUNEL positive rate, cleaved-caspase-3 expression, and B-cell leukemia/lymphoma-2 expression (p < 0.05). …”
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