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1por Gibbs, Brian C., Damerla, Rama Rao, Vladar, Eszter K., Chatterjee, Bishwanath, Wan, Yong, Liu, Xiaoqin, Cui, Cheng, Gabriel, George C., Zahid, Maliha, Yagi, Hisato, Szabo-Rogers, Heather L., Suyama, Kaye L., Axelrod, Jeffrey D., Lo, Cecilia W.“…Here, we show that mutant mice harboring a newly described mutation termed Beetlejuice (Bj) in Prickle1 (Pk1), a PCP component, exhibit developmental phenotypes involving cell polarity defects, including skeletal, cochlear and congenital cardiac anomalies. …”
Publicado 2016
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2“…For these studies, we used the missense allele of Prickle1 named Prickle1(Beetlejuice) (Prickle1(Bj)). The Prickle1(Bj/Bj) mutants are microcephalic and develop enlarged fontanelles between insufficient frontal bones, while the parietal bones are normal. …”
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3por Liu, Dongjing, Ban, Hyo-Jeong, El Sergani, Ahmed M., Lee, Myoung Keun, Hecht, Jacqueline T., Wehby, George L., Moreno, Lina M., Feingold, Eleanor, Marazita, Mary L., Cha, Seongwon, Szabo-Rogers, Heather L., Weinberg, Seth M., Shaffer, John R.“…We used the hypomorphic Prickle1(Beetlejuice) (Prickle1(Bj)) mouse line to directly test the function of Prickle1 on the cranial base and observed wider cranial bases in Prickle1(Bj/Bj). …”
Publicado 2021
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