Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction

por Schulze-Bergkamen, Henning, Fleischer, Binje, Schuchmann, Marcus, Weber, Achim, Weinmann, Arndt, Krammer, Peter H, Galle, Peter R
Publicado 2006

Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy

por Rahbari, Nuh N, Reissfelder, Christoph, Schulze-Bergkamen, Henning, Jäger, Dirk, Büchler, Markus W, Weitz, Jürgen, Koch, Moritz
Publicado 2014

Liver cancers with stem/progenitor-cell features – a rare chemotherapy-sensitive malignancy

por Köhler, Bruno Christian, Waldburger, Nina, Schlamp, Kai, Jäger, Dirk, Weiss, Karl Heinz, Schulze-Bergkamen, Henning, Schirmacher, Peter, Springfeld, Christoph
Publicado 2017

Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

por Koehler, Bruno Christian, Scherr, Anna-Lena, Lorenz, Stephan, Elssner, Christin, Kautz, Nicole, Welte, Stefan, Jaeger, Dirk, Urbanik, Toni, Schulze-Bergkamen, Henning
Publicado 2014

Beyond Cell Death – Antiapoptotic Bcl-2 Proteins Regulate Migration and Invasion of Colorectal Cancer Cells In Vitro

por Koehler, Bruno Christian, Scherr, Anna-Lena, Lorenz, Stephan, Urbanik, Toni, Kautz, Nicole, Elssner, Christin, Welte, Stefan, Bermejo, Justo Lorenzo, Jäger, Dirk, Schulze-Bergkamen, Henning
Publicado 2013

Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling

por Koehler, Bruno Christian, Jassowicz, Adam, Scherr, Anna-Lena, Lorenz, Stephan, Radhakrishnan, Praveen, Kautz, Nicole, Elssner, Christin, Weiss, Johanna, Jaeger, Dirk, Schneider, Martin, Schulze-Bergkamen, Henning
Publicado 2015

An undifferentiated carcinoma at Klatskin-position with long-term complete remission after chemotherapy

por Köhler, Bruno Christian, Goeppert, Benjamin, Waldburger, Nina, Schlamp, Kai, Sauer, Peter, Jäger, Dirk, Weiss, Karl Heinz, Macher-Göppinger, Stephan, Schulze-Bergkamen, Henning, Schirmacher, Peter, Springfeld, Christoph
Publicado 2018

Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells

por Scherr, Anna-Lena, Jassowicz, Adam, Pató, Anna, Elssner, Christin, Ismail, Lars, Schmitt, Nathalie, Hoffmeister, Paula, Neukirch, Lasse, Gdynia, Georg, Goeppert, Benjamin, Schulze-Bergkamen, Henning, Jäger, Dirk, Köhler, Bruno Christian
Publicado 2020

Phase I study of tomuzotuximab, a glycoengineered therapeutic antibody against the epidermal growth factor receptor, in patients with advanced carcinomas

por Fiedler, Walter, Cresta, Sara, Schulze-Bergkamen, Henning, De Dosso, Sara, Weidmann, Jens, Tessari, Anna, Baumeister, Hans, Danielczyk, Antje, Dietrich, Bruno, Goletz, Steffen, Zurlo, Alfredo, Salzberg, Marc, Sessa, Cristiana, Gianni, Luca
Publicado 2018

Nuclear Expression of the Deubiquitinase CYLD Is Associated with Improved Survival in Human Hepatocellular Carcinoma

por Welte, Stefan, Urbanik, Toni, Elßner, Christin, Kautz, Nicole, Koehler, Bruno Christian, Waldburger, Nina, Bermejo, Justo Lorenzo, Pinna, Federico, Weiss, Karl-Heinz, Schemmer, Peter, Jaeger, Dirk, Longerich, Thomas, Breuhahn, Kai, Schulze-Bergkamen, Henning
Publicado 2014

Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications

por Bashari, Muhammad Hasan, Fan, Fengjuan, Vallet, Sonia, Sattler, Martin, Arn, Melissa, Luckner-Minden, Claudia, Schulze-Bergkamen, Henning, Zörnig, Inka, Marme, Frederik, Schneeweiss, Andreas, Cardone, Michael H., Opferman, Joseph T., Jäger, Dirk, Podar, Klaus
Publicado 2016

Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach

por Flanagan, L, Meyer, M, Fay, J, Curry, S, Bacon, O, Duessmann, H, John, K, Boland, K C, McNamara, D A, Kay, E W, Bantel, H, Schulze-Bergkamen, H, Prehn, J H M
Publicado 2016

Bcl-x(L) is an oncogenic driver in colorectal cancer

por Scherr, Anna-Lena, Gdynia, Georg, Salou, Mariam, Radhakrishnan, Praveen, Duglova, Katarina, Heller, Anette, Keim, Sophia, Kautz, Nicole, Jassowicz, Adam, Elssner, Christin, He, You-Wen, Jaeger, Dirk, Heikenwalder, Mathias, Schneider, Martin, Weber, Achim, Roth, Wilfried, Schulze-Bergkamen, Henning, Koehler, Bruno Christian
Publicado 2016

A multicentre, phase IIa study of zolbetuximab as a single agent in patients with recurrent or refractory advanced adenocarcinoma of the stomach or lower oesophagus: the MONO study

por Türeci, O, Sahin, U, Schulze-Bergkamen, H, Zvirbule, Z, Lordick, F, Koeberle, D, Thuss-Patience, P, Ettrich, T, Arnold, D, Bassermann, F, Al-Batran, S E, Wiechen, K, Dhaene, K, Maurus, D, Gold, M, Huber, C, Krivoshik, A, Arozullah, A, Park, J W, Schuler, M
Publicado 2019

Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer

por Scherr, Anna-Lena, Mock, Andreas, Gdynia, Georg, Schmitt, Nathalie, Heilig, Christoph E., Korell, Felix, Rhadakrishnan, Praveen, Hoffmeister, Paula, Metzeler, Klaus H., Schulze-Osthoff, Klaus, Illert, Anna L., Boerries, Melanie, Trojan, Jörg, Waidmann, Oliver, Falkenhorst, Johanna, Siveke, Jens, Jost, Philipp J., Bitzer, Michael, Malek, Nisar P., Vecchione, Loredana, Jelas, Ivan, Brors, Benedikt, Glimm, Hanno, Stenzinger, Albrecht, Grekova, Svetlana P., Gehrig, Tobias, Schulze-Bergkamen, Henning, Jäger, Dirk, Schirmacher, Peter, Heikenwalder, Mathias, Goeppert, Benjamin, Schneider, Martin, Fröhling, Stefan, Köhler, Bruno C.
Publicado 2020

MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice

por Healy, Marc E., Boege, Yannick, Hodder, Michael C., Böhm, Friederike, Malehmir, Mohsen, Scherr, Anna-Lena, Jetzer, Jasna, Chan, Lap Kwan, Parrotta, Rossella, Jacobs, Kurt, Clerbaux, Laure-Alix, Kreutzer, Susanne, Campbell, Andrew, Gilchrist, Ella, Gilroy, Kathryn, Rodewald, Ann-Katrin, Honcharova-Biletska, Hanna, Schimmer, Roman, Vélez, Karelia, Büeler, Simone, Cammareri, Patrizia, Kalna, Gabriela, Wenning, Anna S., McCoy, Kathy D., Gomez de Agüero, Mercedes, Schulze-Bergkamen, Henning, Klose, Christoph S.N., Unger, Kristian, Macpherson, Andrew J., Moor, Andreas E., Köhler, Bruno, Sansom, Owen J., Heikenwälder, Mathias, Weber, Achim
Publicado 2020

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

por Boege, Yannick, Malehmir, Mohsen, Healy, Marc E., Bettermann, Kira, Lorentzen, Anna, Vucur, Mihael, Ahuja, Akshay K., Böhm, Friederike, Mertens, Joachim C., Shimizu, Yutaka, Frick, Lukas, Remouchamps, Caroline, Mutreja, Karun, Kähne, Thilo, Sundaravinayagam, Devakumar, Wolf, Monika J., Rehrauer, Hubert, Koppe, Christiane, Speicher, Tobias, Padrissa-Altés, Susagna, Maire, Renaud, Schattenberg, Jörn M., Jeong, Ju-Seong, Liu, Lei, Zwirner, Stefan, Boger, Regina, Hüser, Norbert, Davis, Roger J., Müllhaupt, Beat, Moch, Holger, Schulze-Bergkamen, Henning, Clavien, Pierre-Alain, Werner, Sabine, Borsig, Lubor, Luther, Sanjiv A., Jost, Philipp J., Weinlich, Ricardo, Unger, Kristian, Behrens, Axel, Hillert, Laura, Dillon, Christopher, Di Virgilio, Michela, Wallach, David, Dejardin, Emmanuel, Zender, Lars, Naumann, Michael, Walczak, Henning, Green, Douglas R., Lopes, Massimo, Lavrik, Inna, Luedde, Tom, Heikenwalder, Mathias, Weber, Achim
Publicado 2017