“…In contrast, TFAM-KD-C expressed a higher extracellular acidification rate (ECAR)/OCR(BR) ratio (p = 0.050) and a faster wound healing migration at 6, 12, and 18 h, respectively (all with p = 0.050). Beyond a threshold, the decrease in mtDNA copy number, the mtDNA D310 mutation, and mitochondrial dysfunction were involved in the carcinogenesis and progression of GACs. …”
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“…CONCLUSION: Assessment of clinically meaningful benefit and additional responder analyses provide further support for flibanserin's efficacy beyond numerical improvements in endpoint measures. …”
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“…Analysis of participant data and relevant policy documents moved beyond coding to theorising and thus to the abstraction of key concepts. …”
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“…The mPFS, mOS, ORR, and DCR were 10.6 months, 15.8 months, 42.3%, and 88.6% of first-line anti-PD1/PDL1 and 3.0 months, 9.1 months, 11.6%, and 51.1% of second-line therapy or beyond, respectively. There were 80.6% and 34.0% of the patients suffering any-grade AEs and grade 3–4 AEs. …”
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“…Using the largest samples to date and novel statistical tools, we aimed to determine the extent to which migraine’s polygenic architecture overlaps with bipolar disorder, depression and schizophrenia beyond genetic correlation, and to identify shared genetic loci. …”
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“…Conclusion: NOX66 with (177)Lu-PSMA-617 is a safe and feasible strategy in men being treated with third-line therapy and beyond for mCRPC. PSMA SUV(mean), PSMA-avid tumor volume, and duration of treatment with ASI were independently associated with outcome.…”
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“…BACKGROUND: There is a global emphasis on expanding data collection for joint replacement procedures beyond implant attributes and progression to revision surgery. …”
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“…Future research focusing on the ways in which SAM use confers acute risk, above and beyond the risks associated with separate consumption of alcohol and marijuana, is needed for understanding potential targets for intervention.…”
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“…Revising rehabilitation to extend beyond traditional musculoskeletal strengthening to include focus on incorporation and maintenance of healthy lifestyle behaviors related to diet and PA should be considered to help patients with ACLR to minimize the potential for negative long-term effects of weight gain following surgery.…”
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“…To ensure future success, health system leaders need to proactively build on their virtual health solutions; advocate for payment, site flexibility, and reimbursement parity for virtual health; and demonstrate continued engagement and boldness to evolve care beyond established models.…”
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“…Psychological readiness to return to sport trended upwards, but didn’t reach statistical significance until later in recovery. Beyond 9 months, physical function and psychological preparedness remain largely unchanged. …”
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“…It has shaken every one from individual to institutes .Sudden application of break in the modern life style and prolong home bounded situation exacerbated the mental health issue beyond the expectation of experts. Pandemic has hampered the life style of all age group specially children ,adolescents and young who are captivated at home . …”
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“…The type of risk-management options planned to be taken up in the future (i.e., beyond the end of the study) and the potential impact of personalised risk estimates on women’s psychosocial health will be collected as secondary-outcome measures. …”
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“…The holistic development process used here, which integrated health information, validated questions, and digital functionality, offers an example that could be applicable in the context of other long-term conditions. Beyond its potential to identify care needs, the tool offers information that confirms experiences and supports answering the questions in the tool. …”
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“…Future research is needed to expand the ability to perform automated multisite data extraction during a PHE and beyond.…”
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“…At present, short videos have gone beyond “watching” and added links with user experience, user psychology, consumer behavior and other factors. …”
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“…Moreover, the prevalence of hypertension increased by 3.7% (OR: 1.037; 95% CI: 1.009-1.065; p = 0.009) and 6.1% (OR: 1.06; 95% CI: 1.033–1.091; p < 0.001), respectively, as per 1-standard deviation (SD) increase in the cholesterol index and non-HDL-C. Beyond that, ROC analysis demonstrated that the cholesterol index and non-HDL-C have a good predictive value for the prevalence of hypertension in women, with under the ROC curve (AUC) of 0.659 and 0.684 and cut-off values of 47.94 and 134.34 mg/dl, accordingly. …”
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“…Our results show that both SNPs and structural variants significantly impact growth, and we therefore recommend that researchers interested in the genotype–phenotype map should strive to go beyond SNPs and incorporate structural variants in their studies as well. …”
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“…Similar associations were observed during the subsequent treatment periods (beyond 90 days) and among older people and those with substance use, except for an increased risk of extrapyramidal symptoms among older people when initiating LAIAs (first 90 days). …”
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“…It may be helpful to include complex experiences with data sources that require learners to go beyond a binary “trustworthy/untrustworthy” distinction, so that learners can become more strategic, nuanced and intentional in forming a variety of trust relationships with different sources. …”
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