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75981por Saban, Marcia R, O'Donnell, Michael A, Hurst, Robert E, Wu, Xue-Ru, Simpson, Cindy, Dozmorov, Igor, Davis, Carole, Saban, Ricardo“…It is particularly unclear whether BCG is capable of altering gene expression in the bladder target organ beyond its well-recognized pro-inflammatory effects and how this relates to its therapeutic efficacy. …”
Publicado 2008
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75982“…RESULTS: Based on recent spatial decision-support technologies, this paper presents a spatio-temporal web-based application that goes beyond GIS applications with regard to speed, ease of use, and interactive analysis capabilities. …”
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75983por Hien, Tran Tinh, Dung, Nguyen Thi, Truong, Nguyen Thanh, Van, Ninh Thi Thanh, Bich Chau, Tran Nguyen, Hoang, Nguyen Van Minh, Nga, Tran Thi Thu, Thuy, Cao Thu, Minh, Pham Van, Binh, Nguyen Thi Cam, Ha, Tran Thi Diem, Toi, Pham Van, Song Diep, To, Campbell, James I., Stockwell, Elaine, Schultsz, Constance, Simmons, Cameron P., Glover, Clare, Lam, Winnie, Marques, Filipe, May, James P., Upton, Anthony, Budhram, Ronald, Dougan, Gordon, Farrar, Jeremy, Vinh Chau, Nguyen Van, Dolecek, Christiane“…No shedding was detected beyond day 3. A positive immune response, defined as 70% increase (1.7 fold change) in LPS specific serum IgG (day 14 or 28) and/or 50% increase (1.5 fold change) in LPS specific serum IgA (day 7 or 14) from baseline was detected in 98 (97%; 95% CI, 92–99%) of 101 M01ZH09 recipients and 8 (16%; 95% CI, 7–29%) of 50 placebo recipients. …”
Publicado 2010
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75984“…Chronomodulation of oxaliplatin has not been extensively studied, and the topic of chronomodulation is beyond the scope of this guideline and is not addressed. …”
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75985por Gurwith, Marc, Lock, Michael, Taylor, Eve M, Ishioka, Glenn, Alexander, Jeff, Mayall, Tim, Ervin, John E, Greenberg, Richard N, Strout, Cynthia, Treanor, John J, Webby, Richard, Wright, Peter F“…We solicited symptoms of reactogenicity daily for 7 days after each vaccination and recorded symptoms that persisted beyond 7 days as adverse events. Primary analysis was per protocol. …”
Publicado 2013
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75986“…Individuals are also reaching beyond the peer-reviewed environment to grey literature using search engines like Google Scholar to access policy documents, consensus reports and conference proceedings. …”
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75987por Azzam, Sausan, Broadwater, Laurie, Li, Shuo, Freeman, Ernest J, McDonough, Jennifer, Gregory, Roger B“…Appropriate homogenization protocols and protein fractionation using anion exchange beads can be employed to reduce sample complexity without introducing significant additional variation into the SELDI mass spectra beyond that inherent in the SELDI- MS method itself. …”
Publicado 2013
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75988por Dupuy, Céline, Perrin, Jean-Baptiste, Bronner, Anne, Calavas, Didier, Hendrikx, Pascal, Fouillet, Anne“…Such a project has demonstrated that scientific community is more and more willing to collaborate beyond the boundaries of these two health fields. …”
Publicado 2013
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75989“…Applying the HHS framework to surveillance expands measures for surveillance quality beyond typical variables (e.g., data quality and analytic capabilities) to desired characteristics of a quality public health system. …”
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75990por Christophersen, Olav Albert“…This radiation-induced taurine depletion can itself have various harmful effects (as will also be the case when taurine depletion is due to other causes, such as alcohol abuse or cancer therapy with cytotoxic drugs), but taurine supplementation has been shown to have radioprotective effects apparently going beyond what might be expected just as a consequence of correcting the harmful consequences of taurine deficiency per se. …”
Publicado 2012
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75991por Moufid, Kamal, Abbaka, Najib, Touiti, Driss, Adermouch, Latifa, Amine, Mohamed, Lezrek, Mohammed“…Only those patients in whom the attempt at passing a guidewire or catheter beyond the calculus failed were included in this study. …”
Publicado 2013
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75992por Lamberg-Allardt, Christel, Brustad, Magritt, Meyer, Haakon E., Steingrimsdottir, Laufey“…Results from this review support that the recommendation in NNR 2004 needs to be re-evaluated and increased for all age groups beyond 2 years of age. We refer to the total intake from food as well as supplements, given minimal sun exposure. …”
Publicado 2013
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75993por Quintero, Gabriel C“…These symptoms include tolerance, withdrawal, drug consumption for alleviating withdrawal, exaggerated consumption beyond original intention, failure to reduce drug consumption, expending a considerable amount of time obtaining or recovering from the substance’s effects, disregard of basic aspects of life (for example, family), and maintenance of drug consumption, despite facing adverse consequences. …”
Publicado 2013
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75994por Korsatko, S., Deller, S., Mader, J. K., Glettler, K., Koehler, G., Treiber, G., Urschitz, M., Wolf, M., Hastrup, H., Søndergaard, F., Haahr, H., Pieber, T. R.“…Duration of action was beyond the clamp duration of 26 h in all subjects. …”
Publicado 2013
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75995por Ilakkuvan, Vinu, Tacelosky, Michael, Ivey, Keith C, Pearson, Jennifer L, Cantrell, Jennifer, Vallone, Donna M, Abrams, David B, Kirchner, Thomas R“…Additionally, zoom tools enable users to see details within photographs and crop tools highlight where within an image a specific object of interest is found, generating a set of photographs that answer specific questions. Beyond such tools, optimizing the number of raters (ie, crowd size) for accuracy and reliability is an important facet of crowdsourced photo annotation. …”
Publicado 2014
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75996“…CONCLUSIONS: During two weather emergencies, New York public officials were able to convey storm-related information that was shared widely beyond existing follower bases, potentially improving situational awareness and disaster response. …”
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75997por Boatright, Jeffrey H., Dalal, Nupur, Chrenek, Micah A., Gardner, Christopher, Ziesel, Alison, Jiang, Yi, Grossniklaus, Hans E., Nickerson, John M.“…The software-based analysis merged 25 to 36 images into one and adjusted settings to record an image suitable for large-scale identification of cell-to-cell boundaries, and then obtained quantitative descriptors of the shape of each cell, its neighbors, and interactions beyond direct cell–cell contact in the sheet. To validate the software, human- and computer-analyzed results were compared. …”
Publicado 2015
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75998por Scott, David L, Ibrahim, Fowzia, Farewell, Vern, O’Keeffe, Aidan G, Walker, David, Kelly, Clive, Birrell, Fraser, Chakravarty, Kuntal, Maddison, Peter, Heslin, Margaret, Patel, Anita, Kingsley, Gabrielle H“…Initial reductions in disease activity were greater with the biologic strategy, but these differences did not persist beyond six months. Remission was seen in 72 patients (44 with biologic strategy; 36 with alternative strategy); 28 patients had serious adverse events (18 and 10, respectively); six and 10 patients, respectively, stopped treatment because of toxicity. …”
Publicado 2015
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75999por He, Jun, Quintana, Megan T, Sullivan, Jenyth, L Parry, Traci, J Grevengoed, Trisha, Schisler, Jonathan C, Hill, Joseph A, Yates, Cecelia C, Mapanga, Rudo F, Essop, M Faadiel, Stansfield, William E, Bain, James R, Newgard, Christopher B, Muehlbauer, Michael J, Han, Yipin, Clarke, Brian A, Willis, Monte S“…However, increasing MuRF2:PPARγ1 (>5:1) beyond physiological levels drove poly-ubiquitin-mediated degradation of PPARγ1 in vitro, indicating large MuRF2 increases may lead to PPAR degradation if found in other disease states. …”
Publicado 2015
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76000por Partridge, Stephanie R, Balestracci, Kate, Wong, Annette TY, Hebden, Lana, McGeechan, Kevin, Denney-Wilson, Elizabeth, Harris, Mark F, Phongsavan, Philayrath, Bauman, Adrian, Allman-Farinelli, Margaret“…Procedural frameworks for recruitment protocols are required, along with systematic reporting of recruitment strategies to reduce unnecessary expenditure and allow for valuable public health prevention programs to go beyond the research setting. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12612000924853; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?…”
Publicado 2015
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