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  1. 76061
    “…The results showed a promising trend in diversifying the application of health education games that go beyond a specific medical condition. However, our findings indicate the need for health education game development and adoption in developing countries and the need to focus on multidisciplinary teamwork in designing effective health education games. …”
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    Health Education Serious Games Targeting Health Care Providers, Patients, and Public Health Users: Scoping Review
  2. 76062
    “…Without vaccines or effective therapeutics for most viruses, very little can be done beyond supportive care. OBJECTIVES: There is a need to identify risk factors for virus acquisition in HCT recipients in order to develop and implement better preventative interventions. …”
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    Early Respiratory Viral Acquisition after Allogeneic Hematopoietic Cell Transplant (HCT)
  3. 76063
    “…This study aims to bridge this information gap and contribute in improving the effectiveness and efficiency of tPITC among children and adolescents in Cameroon and beyond. METHODS: In three ART clinics where tPITC was previously inexistent, we introduced the routine implementation of this strategy by inviting parents living with HIV/AIDS in care to have their biological children (6 weeks-19 years) HIV-tested. …”
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    Parental and child-level predictors of HIV testing uptake, seropositivity and treatment initiation among children and adolescents in Cameroon
  4. 76064
    “…Data from EHRs did not contribute substantial additional evidence of opioid tolerance beyond the data found in prescription claims. Future research is needed to understand the clinical rationale behind these observed prescribing patterns and to quantify the risk of harm to patients associated with potentially inappropriate prescribing.…”
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    Assessment of Potentially Inappropriate Prescribing of Opioid Analgesics Requiring Prior Opioid Tolerance
  5. 76065
    “…Detainees’ access to medical services is already limited and overcrowding poses a threat of massive contagion. Beyond the health impact of the crisis, the tightening of prison conditions worries. …”
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    Prisons confinées : quelles conséquences pour les soins psychiatriques et la santé mentale des personnes détenues en France ?
  6. 76066
    “…Patients self-administered 75 mg SC TE weekly during the titration phase; blinded dose-adjustments in 25 mg increments occurred at pre-defined time points beyond the sixth dose. The primary endpoint of this study was the percentage of patients achieving an average serum T concentration (C(avg0-168h)) of 300 to 1,100 ng/dL at week 12. …”
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    SAT-037 Effect of Weight on Serum Testosterone with Subcutaneous Testosterone Enanthate in Men with Testosterone Deficiency
  7. 76067
    “…Conclusions: By examining a large cohort of patients with an unbiased, whole-transcriptome RNA-seq assay, we identified potentially actionable kinase fusions in thyroid nodules beyond those described in TCGA. All fusions described here are either novel and not previously reported, rarely reported in one or two case studies, or not described in thyroid cancers. …”
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    OR28-04 Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates
  8. 76068
    “…Clinical and functional changes beyond 6 months remain to be analyzed. DISCUSSION: Our results add to growing evidence that individuals who have experienced a first episode of psychosis benefit from participating in comprehensive interventions that can improve clinical symptoms, function and quality of life. …”
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    T244. FURTHER EVIDENCE SUPPORTING COORDINATED SPECIALTY CARE FOR EARLY PSYCHOSIS: FINDINGS FROM THE SAMHSA SUPPORTED PENN PSYCHOSIS EVALUATION AND RECOVERY CENTER (PERC)
  9. 76069
    “…However, mechanisms underlying AP-induced weight gain and other abnormalities are poorly understood. Beyond AP-metabolic adverse effects, intrinsic metabolic dysregulation may characterize schizophrenia spectrum illnesses, although this has been difficult to disentangle from the multitude of lifestyle and medication factors that characterize disease course. …”
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    S89. INVESTIGATING METABOLIC DYSFUNCTION AND METABOLOMIC PROFILE CHANGES IN ANTIPSYCHOTIC NAIVE PATIENTS
  10. 76070
    “…Five patients matched for age, D-dimer value and SOFA score formed the control group. Beyond standard of care, treated patients received 25 μg/Kg/body weight tirofiban as bolus infusion, followed by a continuous infusion of 0.15 μg/Kg/body weight per minute for 48 hours. …”
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    Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study
  11. 76071
    “…Given multiple possible dosing schedules and the potential benefit of this regimen for patients with defective DNA repair beyond BRCA, we sought to find the recommended phase II dose (RP2D) and schedule of veliparib in combination with carboplatin in patients with advanced breast cancer, either triple‐negative (TNBC) or hormone receptor (HR)‐positive, human epidermal growth receptor 2 (HER2) negative with defective Fanconi anemia (FA) DNA‐repair pathway based on FA triple staining immunofluorescence assay. …”
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    Phase I Study of Veliparib on an Intermittent and Continuous Schedule in Combination with Carboplatin in Metastatic Breast Cancer: A Safety and [18F]‐Fluorothymidine Positron Emission Tomography Biomarker Study
  12. 76072
    “…Samples from muco-positive subjects also shown a ~9-fold variation in salivary IgA levels, with elevated salivary IgA observed beyond three months after onset of symptoms. We observed a correlation (r=0.4405) between salivary IgA levels and COVID-19 disease severity. …”
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    Salivary anti-SARS-CoV-2 IgA as an accessible biomarker of mucosal immunity against COVID-19
  13. 76073
    “…CONCLUSIONS: Cardiac injury commonly occurs in critically ill COVID-19 patients, with increased levels of hs-cTnI beyond day 3 since admission portending a poor prognosis. …”
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    Longitudinal correlation of biomarkers of cardiac injury, inflammation, and coagulation to outcome in hospitalized COVID-19 patients
  14. 76074
    “…Relative to HIV‐negative respondents, HIV‐unknown respondents were less educated (some college aRRR = 0.10, 95% CI = 0.02 to 0.37, beyond college aRRR = 0.31, 95% CI = 0.09 to 0.99, vs. high school or below respectively), had lower HIV knowledge (aRRR = 0.30, 95% CI = 0.20 to 0.71), and were less communicative about safer sex (ARR = 0.29, 95% CI = 0.09 to 0.92). …”
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    Differences in HIV risk and healthcare engagement factors in Filipinx transgender women and cisgender men who have sex with men who reported being HIV negative, HIV positive or HIV unknown
  15. 76075
    “…Overall, we foresee that the results could encourage researchers to examine beyond the presented features into other additional features of the self-recorded data, for example, continuous glucose monitoring features and physical activity data, on a large scale.…”
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    A Novel Approach for Continuous Health Status Monitoring and Automatic Detection of Infection Incidences in People With Type 1 Diabetes Using Machine Learning Algorithms (Part 2): A Personalized Digital Infectious Disease Detection Mechanism
  16. 76076
    “…Although the algorithm did not enhance identification of individual neonates with seizures beyond conventional EEG, recognition of seizure hours was improved with use of ANSeR. …”
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    A machine-learning algorithm for neonatal seizure recognition: a multicentre, randomised, controlled trial
  17. 76077
    “…However, some follow-up data failed to show any sustained effects beyond the post intervention time point. Data on mechanisms of change and cost-effectiveness were also lacking, precluding further analysis. …”
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    Digital Interventions for Screening and Treating Common Mental Disorders or Symptoms of Common Mental Illness in Adults: Systematic Review and Meta-analysis
  18. 76078
    “…CONCLUSIONS AND RELEVANCE: Oxymetazoline, 0.1%, was associated with positive outcomes and was well tolerated in phase 3 trials after instillation at days 1 and 14, demonstrating its potential promise for the treatment of acquired ptosis, although further study is needed to elucidate the clinical relevance of these findings beyond 6 weeks.…”
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    Association of Oxymetazoline Hydrochloride, 0.1%, Solution Administration With Visual Field in Acquired Ptosis: A Pooled Analysis of 2 Randomized Clinical Trials
  19. 76079
    “…CONCLUSIONS: Value in the assessments of eHealth interventions need to be considered beyond economic terms, perceptions, or behavior changes. …”
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    Identifying the Value of an eHealth Intervention Aimed at Cognitive Impairments: Observational Study in Different Contexts and Service Models
  20. 76080
    “…Age, HIV status, grade, longer treatment times (>42-day median), and lack of a pre- or post-treatment PET scan were not associated with the outcome. Dose escalation beyond 54 Gy was not significant, even among locally advanced tumors. …”
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    Patient Outcomes With Dose Escalation Using Modern Radiotherapy Techniques: A Retrospective Review of Anal Cancer Treated at a Large Academic Institution Between 2010 and 2016
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