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“…This review summarizes the biology, clinical management, and pharmacological perspectives of these complex tumors.…”
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“…Synthetic biology promises to create high-impact solutions to challenges in the areas of biotechnology, human/animal health, the environment, energy, materials and food security. …”
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“…The identification of biomarkers is further complicated by the diversity of biological living situations, lifestyle activities and medical treatments. …”
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“…In order to reach the point where our experimental understanding of the antioxidant activity of CNPs can be translated into useful therapeutics in the clinic, it is necessary to evaluate the most current evidence that supports CNP antioxidant activity in biological systems. Accordingly, the aims of this review are three-fold: (1) To describe the putative reaction mechanisms and physicochemical surface properties that enable CNPs to both scavenge reactive oxygen species (ROS) and to act as antioxidant enzyme-like mimetics in solution; (2) To provide an overview, with commentary, regarding the most robust design and synthesis pathways for preparing CNPs with catalytic antioxidant activity; (3) To provide the reader with the most up-to-date in vitro and in vivo experimental evidence supporting the ROS-scavenging potential of CNPs in biology and medicine.…”
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“…CONCLUSIONS: We conclude with a series of linked recommendations for improving reproducibility in computational biology through communication, policy, education and research practice. …”
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“…This review attempts at summarizing the intricacies between Wnt signaling and cancer stem cell biology with a special emphasis on colorectal cancer.…”
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“…One of the goals in Synthetic Biology is to recapitulate biological complexity from simple systems made from biological molecules–gaining a deeper understanding of life in the process. …”
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“…Lastly, we connected these theoretical results to real biological networks that demonstrate specificity in the context of promiscuity. …”
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“…This review mainly focuses on molecular biology and infection of HEV and offers perspective new insight of this enigmatic virus.…”
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“…Structural biology comprises a variety of tools to obtain atomic resolution data for the investigation of macromolecules. …”
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“…This review aims to gather and discuss the latest data about pathological and biological consequences in the radiation-exposed heart in a comprehensive manner. …”
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