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4301
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4302
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4303“…In many applications, it does not suffice that an algorithm just detects a biological signal in the sequence, but it should also provide means to interpret its solution in order to gain biological insight. …”
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4304“…BACKGORUND: The completion of the Human Genome Project has resulted in large quantities of biological data which are proving difficult to manage and integrate effectively. …”
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4305“…BACKGROUND: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. …”
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4306“…In this paper we propose a data based algorithm to marry existing biological knowledge (e.g., functional annotations of genes) with experimental data (gene expression profiles) in creating an overall dissimilarity that can be used with any clustering algorithm that uses a general dissimilarity matrix. …”
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4307
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4308
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4309
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4310
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4311“…The in vivo biological activity of various fractions and components of haematoporphyrin derivative (HpD) have been determined by measuring the depth of necrosis of implanted tumours in mice exposed to light after the administration of standard doses of porphyrins dissolved in alkali. …”
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4312
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4313“…Changes in the skeletal system, which include age-related bone and joint remodeling, can potentially be used as a biomarker of biological aging. The aim of the present study was to investigate the extent and mode of inheritance of skeletal biomarker of biological aging—osseographic score (OSS), in a large sample of ethnically homogeneous pedigrees. …”
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4314por Meijer, Jiska M., Pijpe, Justin, Bootsma, Hendrika, Vissink, Arjan, Kallenberg, Cees G. M.“…The gain in knowledge regarding the cellular mechanisms of T and B lymphocyte activity in the pathogenesis of Sjögren’s syndrome (SS) and the current availability of various biological agents (anti-TNF-α, IFN- α, anti-CD20, and anti-CD22) have resulted in new strategies for therapeutic intervention. …”
Publicado 2007
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4315
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4316Publicado 1978“…The effects of FC were identical to those of unlabeled colchicine in all biological systems tested. The results demonstrate that FC may be substituted for colchicine in biological experiments without significant loss in specificity or effectiveness.…”
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4317
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4318por Avery, Oswald T.“…That the organisms of these three subgroups are biologically related to Pneumococcus Type II is shown by the following facts: (a) Agglutination with Antipneumococcus Serum II. …”
Publicado 1915
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4319
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4320